Manish Jain

More Than Serotonin: How Psychedelics Engage the Whole Brain #psychedelics neurosciencenews.com/psychedelics-b…

More Than Serotonin: How Psychedelics Engage the Whole Brain - Neuroscience News neurosciencenews.com/psychedelics-b…

Hugely important work from ⁦@zenbrainest⁩ that opens new doors (and immensely complicates the picture!) The polypharmacology of psychedelics reveals multiple targets for potential therapeutics: Neuron cell.com/neuron/abstrac…

It's finally out! Our "somewhat" thorough study on psychedelic polypharmacology. Congrats to @jainmk6 @zenbrainest and everyone else involved! sciencedirect.com/science/articl… #psychedelics

EVERYTHING YOU EVER WANTED TO KNOW ABOUT #PSYCHEDELICS AND THINGS YOU NEVER THOUGHT ABOUT! cell.com/neuron/abstrac…

I am excited to share our latest work in @Neuron exploring the pharmacology of psychedelics. I am deeply grateful to my PI, Prof. Bryan Roth, @zenbrainest, for his exceptional guidance, and to all my co-authors for their valuable collaborations.

Molecular glues becoming a thing in the GPCR world! nature.com/articles/s4142… nature.com/articles/s4142…

I’m in Montana giving a talk at my undergraduate college

Nice perspective on new GPCR strutures! nature.com/articles/s4142…

Happy to share another article on selective non-catechol agonists for D1R! Functionally Selective Dopamine D1 Receptor Endocytosis and Signaling by Catechol and Noncatechol Agonists | Biochemistry pubs.acs.org/doi/10.1021/ac…

#psychedelics! Excellent piece of work on psychedelics explaining their molecular details of binding to 5HT2A receptor. Also this is my first co-first author paper from the Roth lab. Congratulations @rgumpper @RothLabUNC! nature.com/articles/s4146…

Happy to share that this work on the structural biology of #psychedelics is finally out! Big shout out to all involved, especially @zenbrainest for all of the support! The structural diversity of psychedelic drug actions revealed | Nature Communications nature.com/articles/s4146…

Super cool study on psychedelic's action on 5-HT2A. Congrats! @rgumpper @zenbrainest and @ Manish.

Yuuge paper on #psychedelics The structural diversity of psychedelic drug actions revealed nature.com/articles/s4146…

Our perspective on this emerging outlook on GPCR allosteric modulators that facilitate protein-protein interactions is out now in Biochemistry. They are, in fact, molecular glues with great promise for modulating biased signaling. Check it out! pubs.acs.org/doi/10.1021/ac…

News from @RothLabUNC miragenews.com/gene-therapy-b…

Looking forward to this! @karolinskainst

Lab logo from some years ago:

Congratulations to @zenbrainest of @UNC_PHCO for delivering a great Frank H. Westheimer Prize Lecture this afternoon at @HarvardCCB! chemistry.harvard.edu/news/bryan-rot…

Wonderful visit. Highlight was interacting with students and postdocs!