Danny IncaRNAto
@incaRNAtolab
Associate Professor in Molecular Genetics @univgroningen @ResearchGbb | CSO @serna_bio | #RNA structure ensembles & dynamics | 🦋 http://incarnatolab.bsky.social
Very excited to share our latest preprint, led by rockstar post-doc @i_borovska. Our humble attempt to begin exploring #RNA secondary structure ensembles in a living cell (biorxiv.org/content/10.110…) (1/n)
Many proteins bind RNA, yet we still don’t know what RNAs most bind because methods map one RBP at a time. In @CellCellPress, with the Jovanovic lab, we describe SPIDR – a method for mapping the RNA binding sites of dozens of RBPs in a single experiment. sciencedirect.com/science/articl…
🚨New Forum podcast just dropped🚨 Barbara Cheifet speaks with Marie Lopez and Brian Hie about how foundation models are being used for analysis of the function and structure of DNA, RNA and proteins, and how they're being developed for clinical use shows.acast.com/forum/episodes…
Calling all #RNA & #AI researchers! 🧬🤖 Submissions are open for the new open‑access collection “Exploring RNA Biology with Deep Learning Algorithms” in RNA Biology that I am guest editing with @YiliangDing 📄⬇️ michaelwolfinger.com/blog/2025/blog… #DeepLearning #bioinformatics #CompBio
Our new paper is out in PNAS! We show that competition for binding to the Hfq matchmaker disfavors mismatched sRNA-mRNA combinations while allowing matched sRNA-mRNAs to form stable pairs. Kudos to Jorjethe Roca and Yi-Lan Chen for their fantastic work! doi.org/10.1073/pnas.2…
New paper alert! Congratulations to Manju Ojha et al. We have shown how structural plasticity of RRE modulates nuclear export of HIV -1 RNAs. Mutation-driven RRE stem-loop II conformational change induces HIV-1 nuclear export dysfunction academic.oup.com/nar/article/53…
The IncaRNAto lab is seeking a motivated #PhD candidate, interested in studying #RNA structural ensemble dynamics in living cells. Here's the link to the vacancy: rug.nl/about-ug/work-…. Please share!
Genome-Wide (GW): an interactive browser for ultrafast chromosome-scale genomics data visualization. nature.com/articles/s4159…
New online! Structure of fungal tRNA ligase Trl1 with RNA reveals conserved substrate-binding principles bit.ly/3T4Zr9d
#HiringAlert Looking to tackle computational challenges of RNA folding and binding? Come build new RNA algorithms as a #postdoc in my lab! More info: euraxess.ec.europa.eu/jobs/350755 #Academia #Position #Job #Research #RNA #Structure #3D #Bioinformatics #Poland #Warsaw #IMolPAS #NCN