The Koirala Lab

@KoiralaLab

RNA is a tremendously important yet mysterious biomolecule with diverse functions. Our lab at UMBC aims to dig deeper into the RNA structures and functions!

Joined April 2022

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332Followers

The Koirala Lab Retweeted

Manju Ojha@Manju_Shree90 · Jul 7

I am thrilled to share that our latest research article focusing on the structural plasticity of HIV-1 RRE has been published . I would like to thank my supervisor, co-authors and collaborators. @KoiralaLab academic.oup.com/nar/article/53…

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The Koirala Lab@KoiralaLab · Jul 7

Our lab in UMBC news! Awesome story about graduate-undergraduate collaboration and mentorship! UMBC’s Koirala Lab celebrates students’ award-winning RNA research and peer mentorship umbc.edu/stories/studen…

KoiralaLab's tweet card. A talented trio of students has earned accolades for their innovative work with Deepak Koirala, assistant professor of chemistry and biochemistry. Their awards are replicating like the RNA they...

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The Koirala Lab@KoiralaLab · Jul 5

New paper alert! Congratulations to Manju Ojha et al. We have shown how structural plasticity of RRE modulates nuclear export of HIV -1 RNAs. Mutation-driven RRE stem-loop II conformational change induces HIV-1 nuclear export dysfunction academic.oup.com/nar/article/53…

KoiralaLab's tweet card. Abstract. The Rev response element (RRE) forms an oligomeric complex with the viral protein Rev to facilitate the nuclear export of intron-retaining viral

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The Koirala Lab@KoiralaLab · Jun 12

haven't posted in a while but happy to share the news I've received the Beckman Young Investigator award 🥳 grateful for the hard work of my team pushing the barriers of understanding #Rloop biology and for this recognition🧬

BBeckman Foundation@BeckmanFnd · Jun 11

Meet Charles Bou-Nader, PhD, 2025 Beckman Young Investigator Awardee from @emorymedicine! Read more about this news from Beckman Foundation: ow.ly/Bc7Y50W85bS #BYI

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The Koirala Lab@KoiralaLab · Jun 2

It was very rewarding meeting at RNA Society Meeting #RNA25 @RNASociety. Our awesome graduate student Hasan Banna @hbnnbd gave an amazing talk about new RNA imaging tools. Meeting colleagues, students, postdocs and some non-RNA (proteins) friends as well was a great experience!

KoiralaLab's tweet image. It was very rewarding meeting at RNA Society Meeting #RNA25 @RNASociety. Our awesome graduate student Hasan Banna @hbnnbd gave an amazing talk about new RNA imaging tools. Meeting colleagues, students, postdocs and some non-RNA (proteins) friends as well was a great experience!

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The Koirala Lab@KoiralaLab · May 31

A great day of RNA Society Meeting 2025 at San Diego #RNA @RNASociety! Our graduate student Naba Krishna Das @KrishnaNaba presenting his research to expert audiences #UMBC @UMBCChemistry!

KoiralaLab's tweet image. A great day of RNA Society Meeting 2025 at San Diego #RNA @RNASociety! Our graduate student Naba Krishna Das @KrishnaNaba presenting his research to expert audiences #UMBC @UMBCChemistry!

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The Koirala Lab Retweeted

Hasan Al Banna@hbnnbd · May 30

It's fascinating to see that so many people are obsessed with that one biomolecule! #RNA25 @RNASociety

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The Koirala Lab@KoiralaLab · May 30

It’s time to change the title from tenure-track assistant professor to tenured associate professor! Thanks to students, mentors, family, colleagues and friends for their help and support. I am inspired and motivated to serve the science more than ever!

KoiralaLab's tweet image. It’s time to change the title from tenure-track assistant professor to tenured associate professor! Thanks to students, mentors, family, colleagues and friends for their help and support. I am inspired and motivated to serve the science more than ever!

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The Koirala Lab Retweeted

Hasan Al Banna@hbnnbd · May 16

Congrats to @KrishnaNaba for defending his doctoral thesis and being the first one from the @KoiralaLab !

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The Koirala Lab@KoiralaLab · May 15

The first PhD from The Koirala Lab!! Congratulations Dr. Naba Krishna Das! The lab is proud of you and your accomplishments. Wish you all the best for future endeavors!

KoiralaLab's tweet image. The first PhD from The Koirala Lab!! Congratulations Dr. Naba Krishna Das! The lab is proud of you and your accomplishments. Wish you all the best for future endeavors!

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The Koirala Lab Retweeted

Jinwei Zhang Lab@jinweizhang · May 12

How to find fantastic new #RNAs? The J2 antibody is the gold standard to detect, map & enrich dsRNAs. Co-led by @CharlesBNader, Kevin Juma, Ankur Bothra & Steve Leppla’s lab, we visualize how J2 recognizes dsRNA and define its epitope, specificity & bias. doi.org/10.1101/2025.0….

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The Koirala Lab Retweeted

Manju Ojha@Manju_Shree90 · May 9

I am honored and deeply grateful to the College of Natural and Mathematical Sciences, @UMBC for selecting me as the recipient of the Robert F. Steiner Award for Outstanding Biochemistry Graduate Student in the Department of Chemistry. @KoiralaLab

The Koirala Lab@KoiralaLab · May 9

What a rewarding day for the Koirala Lab today! Graduate student, Manju Ojha, gave an excellent talk at FCBIS, and received outstanding biochemistry research award from CNMS at UMBC. Two undergraduates, Megan and Jason, received outstanding research awards! Congratulations!!

KoiralaLab's tweet image. What a rewarding day for the Koirala Lab today! Graduate student, Manju Ojha, gave an excellent talk at FCBIS, and received outstanding biochemistry research award from CNMS at UMBC. Two undergraduates, Megan and Jason, received outstanding research awards! Congratulations!!

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The Koirala Lab@KoiralaLab · May 9

If you want to unfold the same molecule through multiple directions, DNA nanoswitch caliper is the way to go!

WWesley Wong Lab@WesleyWongLab · May 9

New preprint on single-molecule mechanostructural fingerprinting! doi.org/10.1101/2025.0… We use DNA nanoswitch calipers to characterize the geometry and mechanical stability of telomeric DNA G-quadruplexes. #Biophysics #SingleMolecule #Mechanobiology #DNAnanotech

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The Koirala Lab Retweeted

Das Lab@RDasLab · May 6

Our #RNA multimer paper out now in @nature! #cryoEM of 2 distinct nanocages GOLLD and ROOL and membrane-associated OLE. Multimers at ultra-low concentrations, special covariance for cross-molecule kissing loops, and speculation on function nature.com/articles/s4158…. 1/2

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Das Lab@RDasLab · Apr 23

Are RNA 3D models accurate enough to be biologically useful? #CASP16 experimentalists say: not so much. doi.org/10.1101/2025.0… Thanks for leading this paper @rachaelkretsch @AKryshtafovych! 1/2

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The Koirala Lab@KoiralaLab · Apr 16

Our talented undergraduate, Megan, presenting her research at UMBC’s Undergraduate Research and Creative Achievement Day (URCAD)! Lab is proud of you, Megan! #UMBC @UMBCChemistry #RNA @KoiralaLab

KoiralaLab's tweet image. Our talented undergraduate, Megan, presenting her research at UMBC’s Undergraduate Research and Creative Achievement Day (URCAD)! Lab is proud of you, Megan! #UMBC @UMBCChemistry #RNA @KoiralaLab

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The Koirala Lab@KoiralaLab · Apr 12

Excited to run this workshop for @ClubSciWri Register at docs.google.com/forms/d/18jdrC…

CClubSciWri@ClubSciWri · Apr 12

Big news! Our first-ever Popular Science Writing Workshop is here! Are you a PhD, postdoc, or early-career researcher ready to share your excitement about science with the world? This is your moment to learn, connect, and grow. #sciencewriting

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The Koirala Lab Retweeted

IBBR@UMD_IBBR · Apr 9

Registration is now open for IBBR's Second Biennial Structural Biology Day on Wednesday, May 7, 2025 at our facility in Rockville, Maryland. We hope to see you there! go.umd.edu/ibbrsbd25

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The Koirala Lab Retweeted

Craig Cameron Lab@CameronLabUNC · Mar 29

What a great day I had today with trainees and faculty in the Chemistry and Biochemistry department ⁦@UMBC⁩! My thanks to Aaron Smith and Alex Paredes, ⁦@HHMINEWS⁩ Gilliam Fellow, for the invitation and for being such gracious hosts!

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