Tian Ge
@getian107
Associate Professor @CGM_MGH @HarvardMed | Statistical Genetics | Brain Imaging | Precision Medicine
New work led by @EpiHeather on an under-appreciated problem: How selection bias may be warping effect estimates of polygenic risk scores. With @tthaweethai @AnnejaneF @yihansheu Beth Karlson @getian107 @GENES_PK pubmed.ncbi.nlm.nih.gov/37226828/
Excited to share that our new paper in Nature Genetics! Huge thanks to @hailianghuang and @getian107 for supervising this project and to @broadinstitute, @CGM_MGH and @PGCgenetics for supporting the research. rdcu.be/dR0sF
Pleased to share a new preprint led by the amazing @jd_tubbs, in which we developed a real-time PRS construction algorithm that can dynamically update SNP weights to integrate streaming data. Check out Justin's brief thread for more details👇
Introducing real-time PRS-CS! Excited to share our new preprint with @getian107. Optimized for healthcare settings, rtPRS-CS ensures patients receive the most up-to-date genetic risk prediction by dynamically updating PRS weights using streaming data. 1/7 medrxiv.org/content/10.110…
Exciting news! Our latest study has been published in @NatureComms: nature.com/articles/s4146… Congrats and huge thanks to @ChiayenChen, @heikorunz, and all our other co-authors, @getian107, @ToddLencz, @maxzylam, @jimmyzliu, @eatsai for their exceptional contributions!
Thrilled to announce our latest study published in @CellGenomics ! cell.com/cell-genomics/… Big shoutout to our amazing collaborators @ChiayenChen @getian107 @hailianghuang @AnnejaneF and many others! #GWAS #TaiwanBiobank🧬
📢 Today we launch the @PGCGenomics Video Textbook! A structured training program in psychiatric genetics, analysis methods and software tools. Open access, do share widely. #WCPG2023 1/n
I'm delighted to release the first half of my new open-access online textbook in human population genetics: web.stanford.edu/group/pritchar…
Join us virtually Sept 29th-30th for the 3rd Annual Conference on Precision Psychiatry! Students, trainees, interns, and fellows can register for FREE! We are also pleased to offer 7.75 CME credits this year. Register at mghcme.org/Precision2023 #CME #precisionpsychiatry
[1/6] Preprint 🚨“Do the genetic and phenotypic factor structures of psychopathology differ?” “What factors better capture comorbidity and shared etiology across disorders?” “How do factor polygenic scores predict brain & biobehavioral outcomes?“ medrxiv.org/content/10.110…
Check out our speakers and topics! Don’t miss this virtual conference. Registration is free for students and trainees and CME/CE credits available
We are just one month away from the 3rd Annual Conference on Precision Psychiatry: Innovation to Implementation! Register today to reserve your spot. Register at mghcme.org/Precision2023 Check out the conference agenda and more info. at massgeneral.org/psychiatry/res… #innovation #ai
Principles and methods for transferring polygenic risk scores across global populations go.nature.com/3PbbGQ8 #Review
I want to personally invite you to attend our upcoming conference on Precision Psychiatry, bringing together clinicians, researchers, trainees, students, investors, and industry leaders from across the globe Register at mghcme.org/Precision2023 and take 15% off with code NETWORK15
Now published in @NatureGenet: Our exome study on proxy measures of cognitive function, revealing rare, yet large effect genetic contributions. 🙏to all participants & collaborators for their scrutiny & some truly insightful findings rdcu.be/dcZRe
New preprint! We studied how rare protein-coding variants impact cognitive function & linked diseases in @uk_biobank. We identified 8 large-effect cog fx genes, dosage-sensitivity for KDM5B, additivity of rare variant and polygenic risk & more (1/12) medrxiv.org/content/10.110…
Multivariate genomic architecture of cortical thickness and surface area at multiple levels of analysis Kudos to @Andrew_Grotz @wakeworksleep @zhaowenliu_kaka @getian107 @jakob_seidlitz rdcu.be/c6hpy
We have open summer co-op positions at the Human Genetics group at Biogen (Jun. to Dec. 2023). Join us for some exciting scientific projects and learning experience! Please reach out if you're interested in this opportunity. jobs.smartrecruiters.com/Biogen/7439998…
Announcing a new @CGM_MGH faculty search in the area of Psychiatric Genomics and Epidemiology! The new faculty member will be appointed in @MGHPsychiatry and partner with the @StanleyCenter at @broadinstitute Apply here: redcap.partners.org/redcap/surveys…
Happy to announce this year's call for applications supporting our postdoc fellows for the NHGRI-funded MGB T32 Training Program in Precision and Genomic Medicine. cgm.massgeneral.org/training-progr…