Jordan Smoller
@jorsmo
Psychiatry, Genetics, Epidemiology, Precision Medicine. Author of The Other Side of Normal. 3% Neanderthal. Now on BlueSky http://jorsmo.bsky.social
Sad that X/Twitter is losing its value as a place to find and share the latest in science and medicine. I've now joined #BlueskySocial (same @jorsmo handle) as the the mass migration of medTwitter and sciTwitter to Bluesky builds. Hope to see you there. statnews.com/2024/11/21/blu…
A must-read on the impact of defunding biomedical research and healthcare infrastructure nytimes.com/interactive/20…
Great visualization. We Need a Reminder of What the Pre-Vaccine Era Was Like nytimes.com/interactive/20…
“If we survive I will be somewhat surprised,” cnn.com/2025/07/08/hea…
Join us September 23rd for the Hands-on AI in Precision Psychiatry Workshop. 💻 Fully virtual 🕙 10:00am–3:30pm ET 🔗 Sign up: mghcme.org/Precision2025
Hear from Keynote speaker Dr. Marion Leboyer at this year's 5th Annual Conference on Precision Psychiatry! Tune in virtually Sept 25–26, 2025! -FREE registration for students, fellows & trainees -Earn 8 CE credits Register: mghcme.org/Precision2025
🆕📽️Last week's webinar is available now on YouTube! How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors youtu.be/TMCAikdy2dQ?si… Thank you to everyone who joined & @cmoutierMD @lab_jobes @TonyPisani @katespeer1 @jorsmo @mk_nock @afspnational
How polygenic score effects vary by context and interacting contexts with Mihael Cudic @jd_tubbs Tian Ge Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk medrxiv.org/content/10.110…
🚨🧬 New preprint! We tested whether PGS predicted global functioning across psychiatric hospitalization among 5991 people with schizophrenia. medrxiv.org/content/10.110…
Another breakthrough made possible by federal funding The result “is a triumph for the American peoples’ investment in biomedical research” Baby Is Healed With World’s First Personalized Gene-Editing Treatment nytimes.com/2025/05/15/hea…
"The largest number of terminated grants was adminis- tered by the NIMH (n = 128) and the NIMHD (n = 77) (Table 1)." Characterization of Research Grant Terminations at the National Institutes of Health pubmed.ncbi.nlm.nih.gov/40338733/
"let’s be clear: It isn’t institutions that are being punished. It’s the researchers who are the future of science in this country" What am I supposed to say to this generation of young scientists? statnews.com/2025/05/07/us-… via @statnews
Devastating "The National Institutes of Health would take the largest cut in the Trump proposal, losing nearly $18 billion compared to the 2025 budget." Trump proposes billions in cuts to federal health agencies from NIH to CDC statnews.com/2025/05/02/ski… via @statnews
another example of how research = hope nytimes.com/2025/04/27/hea… @ginakolata
In a new study, researchers from @MGHPsychiatry used machine learning to enhance the accuracy of predicting suicide risk. The study was published in @JAMAPsych. Read more: jamanetwork.com/journals/jamap… @drkatebentley @c3k @TaylorABurkePhD @jorsmo
📢Work w/ @c3K @TaylorABurkePhD @jorsmo @DrJBStephens + others📢 Clinicians stratify patients for risk of suicide attempt at above chance levels in routine practice, but statistically incorporating routinely collected info during suicide risk assmt improves predictive accuracy
While clinicians can stratify suicide risk above chance levels, predictive accuracy for future suicide attempts significantly improves when using machine learning to incorporate comprehensive clinical assessment data. ja.ma/3G3Niy2 @drkatebentley
Don't miss this year's conference including @LeboyerMarion Steve Hyman @royperlis @JohnTorousMD Husseini Manji @pshrink and many more. Early bird pricing available till May 1
Early bird pricing now through May 1st! Secure your spot today! The Fifth Annual Conference on Precision Psychiatry is occurring virtually on Thursday, September 25th and Friday, September 26th, 2025. Don't miss this opportunity and register today at mghcme.org/Precision2025
Our new paper on continuous-time, dynamic suicide attempt risk prediction is now published online at @npjDigitalMed. Using a large-scale electronic health records database, we adapt neural ODEs—naturally suited for modeling evolving latent states like suicidal tendencies and…
From @VPrasadMDMPH and colleagues pointing out that median duration of antidepressant RCTs= 8 wks while in real-world median use is 5 years and questioning evidence base for long-term use. Fair point though is this unique to ADs as opposed to say CVD meds? medrxiv.org/content/10.110…