CGM at MGH
@CGM_MGH
Center for Genomic Medicine at Massachusetts General Hospital Harvard Medical School
We are so excited to have you join us @AliceStanton !
Absolutely thrilled to make public that I am joining the @harvardmed Harvard Medical School and MGB @CGM_MGH Center for Genomic Medicine and @MGHNeurology Department of Neurology as an Assistant Professor: stantonlab.info. 🧵
Read about a new study published by CGM Associate Member #NinaGold and team.
In a new study, researchers from @mghfc and colleagues identified a growing list of genetic disorders that are treatable before or immediately after birth. The study was published in @AJHGNews. Read more: massgeneralbrigham.org/en/about/newsr…
So fantastic that @NPR featured the unexplained troublingly high rates of heart disease among S Asian individuals, and our research efforts @ourhealthstudy to address these issues! npr.org/2025/02/11/nx-…
New paper in @Circ_Gen: Traditional models assume genetic risk is constant, but @pnatarajanmd & team including @tigerstatdoc show CAD risk is dynamic. Genomic & clinical factors interact differently across life stages. @cgm_mgh @mghcvrc @mghcvfellows loom.ly/D6zv7IM
Our paper led by J. Shin @MGHCVFellows & @AeronSmallMD @BrighamFellows evaluating the longitudinal penetrance of HCM alleles in the @MassGenBrigham Biobank sciencedirect.com/science/articl… @JACCJournals #JACCAdv
@CGM_MGH faculty @CDAndersonMD and team found polygenic risk scores, combined w/ clinical predictors, can help identify patients most likely to develop atrial fibrillation after stroke @MGH_RI @StrokeAHA_ASA loom.ly/QQQFp8s
Researchers @TalkowskiLab used long-read sequencing and the T2T reference to characterize previously intractable genome rearrangements (e.g. ring chroms, Robertsonian translocations), shining light on their formation and consequences. Paper in @AJHGNews loom.ly/IM3blt8
Recent study by @artschuermans, @mchonig, and @cgm_MGH faculty @pnatarajanmd finds that large-scale analysis of the circulating proteome identifies new biomarkers, suggests therapeutic targets, and improves risk prediction for common cardiac diseases. loom.ly/n6mMKYk
@CGM_MGH Asso Member @patrick_ellinor and team use snRNAseq to dissect the molecular basis of atrial fibrillation (AF) loom.ly/ATzQiXQ @MGHHeartHealth @broadinstitute @NatureComms
We are delighted to announce this year's call for applications for the NHGRI-funded MGB T32 Postdoctoral Training Program in Precision and Genomic Medicine buff.ly/414Xajk Please RT or share w/ those who may be interested.
Investigators at @CGM_MGH, @MassGenBrigham, @broadinstitute @AliciaChagoya @miriam_udler, @AaronLeongSA, @AlisaManningPhD, and @josep_mercader identify rare variants with intermediate effect between common T2D and monogenic diabetes. @NatureGenet loom.ly/bxQKbhc
We are excited to share our latest preprint! We systemically phenotyped, genotyped, and sequenced the Mass General Brigham Biobank (MGBB), including 150K participants with 53K genetic data. medrxiv.org/content/10.110… [preprint] (1/11) @broadinstitute @CGM_MGH @mghcvrc @harvardmed
Glad to share pub @NatureGenet, shared first auth @AliciaChagoya, Philip Schroeder, Ravi Mandla @CGM_MGH @MassGenBrigham @broadinstitute and Jiang Li @GeisingerRsrch, with senior co-authors @miriam_udler @AaronLeongSA @AlisaManningPhD and Lin Mirshahi nature.com/articles/s4158… 👇
Congratulations to @cgm_mgh faculty @royperlis for his appointment as Editor in Chief of @JAMAplusAI !
.@royperlis, MD, MSC, has been appointed Editor in Chief of @JAMAplusAI. Perlis is director of @MassGenHos_CQH and Ronald I. Dozoretz, MD, Endowed Chair at @MGHMedicine, and professor of psychiatry at @harvardmed. To explore JAMA+ AI, visit ja.ma/4dLwfMs.
The deadline to apply for a full time faculty position in Neurogenetics at the @CGM_MGH and @MGHNeurology is October 15th! Send your application in to be considered.
@CGM_MGH and @MGHNeurology are seeking applications for a full-time CGM faculty member with an assistant or associate professor of neurology appointment at @harvardmed! loom.ly/GbLy26E
New paper out by CGM faculty #JeremiahScharf with #DongmeiYu finds utilization of extensive hospital databases could improve the understanding of underdiagnosed illnesses, such as tic disorders. loom.ly/p0K_gqU @MGH_RI
CGM Faculty @heidirehm and colleagues in the @GREGoR_research consortium recently published a manuscript encouraging and providing guidance for clinical labs to begin reporting novel candidate genes during diagnostic genome and exome sequencing.
As part of @GREGoR_research , we are excited to announce new guidance to encourage clinical labs to report novel candidate genes during clinical testing. We give criteria for triaging, sharing, and reporting novel genes through various methods. authors.elsevier.com/c/1jcDA3vlFV4E…
Trust in Physicians and Hospitals During the COVID-19 Pandemic in a 50-State Survey of US Adults in @JAMANetwork by CGM faulty @royperlis and colleagues shows decline. Read the paper loom.ly/0g-ffM8
New research from @austinargen @dalygene @APalotie at @CGM_MGH on #proteomic #aging published in @NatureMedicine. The authors developed a proteomic age clock that is associated with nearly all major chronic diseases and mortality. nature.com/articles/s4159…
CGM Faculty @pnatarajanmd talks with @EricTopol about preventing heart disease
My conversation with @pnatarajanmd on preventing cardiovascular disease is the new Ground Truths podcast —how low to go for LDL cholesterol? — apoB, Lp(a), polygenic risk score, CHIP, role of inflammation —new RNA drugs [sorry, link is in my profile due to X-suppression]