Enrico Orsi
@enricoorsi
Bolognese🇮🇹 in CPH🇩🇰| Metabolic Engineering | Synthetic Biology | @MSCActions postdoc @LabNikel @DTUBiosustain 🧬🦠 formerly @WeTheBarEvenLab🇩🇪 @WUR🇳🇱
Have a look at Helena's thread to better understand the meaning and potential of our most recent publication!
Really happy to share that our work on constructing six glyoxylate / glycolate sensors covering a three order of magnitude concentration range is out now in @NatureComms ! 🔥 Read below to see how we developed the sensors and what they are good for 🥳. nature.com/articles/s4146…
Computation-aided designs enable developing auxotrophic #metabolic #sensors for wide-range glyoxylate and glycolate detection—spearheaded by @enricoorsi w/a choral assembly of cool collaborators @LabNikel @NatureComms #SynBio #OpenAccess nature.com/articles/s4146…
Check this #overview from our @LabNikel to see what we have been up to during this 2024!👇
Wrapping up 2024 and wishing all #biotech and #synbio fellows a well-deserved year-end break! Below is a thread summarizing our group's #publications from this year. 🎉📚
We developed a brand new #CRISPR toolkit for #Cupriavidus #necator, a biotechnological platform for CO2 (and derivatives) valorization. The system is based on self-splicing introns and allows us to get mutants within 48h and with efficiencies up to 80% Check the thread below👇
Wrapping up 2024 and wishing all #biotech and #synbio fellows a well-deserved year-end break! Below is a thread summarizing our group's #publications from this year. 🎉📚
Thrilled to present for the first time our glyoxylate & glycolate sensors to the #Synbio community at #ASBE7—an incredible first public reveal in a planetarium! Not every day you get to share science in such a unique venue. Looking forward to the other sessions' presentations!
Wrapping up 2024 and wishing all #biotech and #synbio fellows a well-deserved year-end break! Below is a thread summarizing our group's #publications from this year. 🎉📚
Researchers have developed a computer-guided method for designing and #engineering #bacteria that can detect the presence of specific #molecules in the #environment. This method will advance the use of bacteria to detect these molecules in industry, environmental samples or…
Streamlined and efficient genome editing in #Cupriavidus necator H16 using an optimised SIBR-Cas system—spearheaded by @dellavallesimo & @enricoorsi & led by Costas Patinios + Wei Huang @TrendsinBiotech #SynBio sciencedirect.com/science/articl…
Check out this breakthrough in #synbio👇🧬🦠
Glad to see my main PhD project finally out @NatureMicrobiol nature.com/articles/s4156… We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.
Paper alert! 🎉 Excited to share this collaboration from my PhD time @wethebarevenlab and @erblabs! We built a new bridge in central metabolism, connecting acetyl-CoA and pyruvate via a novel, engineered pathway. For some personal highlights, come along 🧵 nature.com/articles/s4146…
Ancora a caccia di un (bio)informatico... Se ami l'analisi di dati e la ricerca innovativa, unisciti al nostro team multidisciplinare. Opportunità uniche anche di attività sul campo in ambienti estremi! donatogiovannelli.com/vacancies #sciencejobs #academicjobs #Bioinformatics
I am looking for a post-doc researcher to work on my #ERC project EcoMEMO @Unibo. The position is for 2 years full time starting latest in March 2025, with lots of field and labwork. To apply visit the link bandi.unibo.it/ricerca/assegn… (in italian and english). More info ⬇️
**PhD Funding** We are advertising a PhD studentship to work on interdisciplinary challenges in Synthetic Biology, Robotics, and Control/AI! Happy to answer any questions and discuss what we are doing with anyone interested. #synbio eng.ox.ac.uk/study/research…
An enzymatic cascade for high-yield and stereoselective synthesis of 4-fluoro-L-threonine led by @DeMaria_SynBio & @ManuelNietoDom1 @LabNikel @DTUBiosustain @ChemCatalysis #Fluorine #Biocatalysis #Green #Chemistry Read for free here 👇 authors.elsevier.com/a/1jxL89URZ7rP…
Novel enzyme starts with promiscuity. Excited to share our study that shows how #evolution recruits a single enzyme for multiple purposes, showcasing the plasticity and flexibility of #metabolism. Huge thanks to my colleagues at @erblabs & @mpi_marburg! rdcu.be/dXaqU
beta.ecrcentral.org/resources/mate… Thanks to the new website of @champiDicty I got to know about the existence of this database. Very useful resource with a lot of links useful for career development!
Eight years ago, I joined the lab of an ambitious Israeli scientist who had just started his own group. Arren Bar-Even became one of the most inspiring figures in my life. Throughout my PhD, he taught me everything I know about thermodynamics, kinetics, and synthetic pathways…
Our years of work on nitrogenase assembly paid off! So proud of this paper, which demonstrates the heterologous expression of an active nitrogenase. Thanks to everybody involved for a great team effort! @NatureCatalysis, @HuRibbe, @UCIBioSci, @UCIChemistry doi.org/10.1038/s41929…