Dylan Neel, MD PhD
@dylanvneel
PGY-1 @harvardneuromds | MSTP @HarvardMITmdphd | @IsaacChiuLab | @harvard college alum 🎓| ☕️ 🎾
Excited to share our work, out today in @NeuroCellPress ! We identify the innate immune molecule GSDME as a regulator of mitochondrial damage and axon loss in neurons. Inhibition of GSDME rescues pathology in preclinical models of #ALS. (1/15) urldefense.proofpoint.com/v2/url?u=https…
Biomarker interview with Dr. Eric Green, CEO of @TraceNeuro. Eric and his team are developing a promising targeted therapy for #ALS. Check it out! #neurology #biotech open.substack.com/pub/biomarker/…
Rlly cool study investigating the neuroimmunology of neuropathic pain 🧠 Congrats to the authors!
Excited to share this pre-print from my thesis work. I spent the past few years developing a model of diabetic neuropathy and unexpectedly found that macrophages infiltrate the nerves of diabetic mice and their recruitment is neuroprotective!! biorxiv.org/content/10.110…
Recently, Dr. Merit Cudkowicz sat down for an inspiring conversation with Mass General Brigham Neurology resident Dylan Neel. She discussed how she became interested in neuroscience and her passion for advancing clinical trials in amyotrophic lateral sclerosis (ALS). #ALSResearch
Had the chance to interview Dr. @MeritCudkowicz for Biomarker! We discuss challenges with running clinical trials in #neurology, and advice about mentorship/research for young docs! @harvardneuromds @MassGenBrigham @MassGeneralNews open.substack.com/pub/biomarker/…
Biomarker interview Dr. Robert Baloh, Head of Neuroscience @Novartis Biomedical Research. We discuss his training, exciting targets in #neurology, and challenges with #neuroscience drug development #Biotech #pharma biomarker.substack.com/p/novartis-rob…
You’re in great hands America! Here are the 2025 Harvard/MIT MD-PhD graduates who have dedicated their lives to providing the best care to your families & delivering you medical cures from their groundbreaking science. @NIH @NIHDirector_Jay @HHSGov @SecKennedy @harvardmed @MIT
I recently joined @Nudge as medical director. We're building a world-changing device, with the goal of precisely and non-invasively modulating brain function to improve the lives of as many people as possible.
Our mission is to develop the best technology for interfacing with the brain to improve people’s lives.
Expanded Access Protocol of RNS60 in Amyotrophic Lateral Sclerosis - a new paper from the Healey Center research team is out in Muscle & Nerve. Read it here: onlinelibrary.wiley.com/doi/10.1002/mu… #HealeyHope #ALSResearch
Beyond excited to have matched @harvardneuromds ! Can’t wait to meet my co-residents, learn some cool neurology and hopefully help a lot of patients! #Neurology #Match2025 @MGHNeuroSci @BWHNeurology
Happy #MatchDay! BWH Neurology and @MGHNeurology are thrilled to announce our 2025 Matched Residents. We are excited to welcome the next generation of talent in medicine to #MGB. @harvardneuromds
Congrats to @QuintanaLabHMS authors, especially Atsushi! Was happy to contribute and excited to see the link between CLEC16A and gasdermin-D #MultipleSclerosis
Our study on the protective role of CLEC16A in astrocytes in MS is out today in @NatureNeuro! Congrats to Atsushi and all collaborators! nature.com/articles/s4159…
An old dog is learning new tricks. Will be putting out a couple of rhymes with explanations each month in a series called "There is Poetry in Immunology". A couple of links below: youtube.com/watch?v=nMydLD…
Was a privilege to discuss #neuro drug development with Al Sandrock, and the exciting work going on @VoyagerTx. Check it out on #biomarker open.substack.com/pub/biomarker/…
Excited to share our experience with a multi-center, multi-drug expanded access program (EAP) in #ALS These programs are crucial to get novel therapies to a wider range of patients who do not qualify for RCTs @MuscleAndNerve @WileyNeuro @PaganoniMDPhD doi.org/10.1002/mus.28…
Terrific to interview Sujal Shah, CEO of @CymaBay (@GileadSciences) about his career and the development of Seladelpar for primary biliary cirrhosis #pbc Amazing to hear the story from Sujal! #biotech @ldtimmerman @timmermanreport timmermanreport.com/2024/04/how-cy…
F-Prime's Alex Pasteur sat down with @dylanvneel to discuss his career journey, lessons learned as a life science investor, and what excites him about the future of the #radiopharmaceutical industry including our investment in @artbio_inc. Learn more: bit.ly/3UanViR
Biomarker interview with Adam Koppel, Partner @BainCapital Life Sciences. #biotech #science biomarker.substack.com/p/bcls-adam-ko…
I enjoyed a wide-ranging discussion with @dylanvneel on my personal and professional journey for his BioMarker Blog. biomarker.substack.com/p/scan-health-…
Immunology Cheat Sheet: basic bio, clinical dev and upcoming trials for most exciting I&I assets in 2023-24. #biomarker open.substack.com/pub/biomarker/…
Really nice work suggesting a role for GSDME in viral host defense in the CNS 🦠 🧠 from Soren Paludan lab ER stress induces caspase‐2‐tBID‐GSDME‐dependent cell death in neurons lytically infected with herpes simplex virus type 2 | The EMBO Journal embopress.org/doi/full/10.15…