Sara Hakim
@sarainthelab
Interested in neuroimmune interactions, pain, and diabetic neuropathy | @Harvard Ph.D. @UCSanDiego B.S. | 🇪🇬🇺🇸🌍
My PhD work is finally out in @Nature this week! Again, really grateful for all the support I received from mentors and labmates to get this over the finish line. The revision process has uncovered a few more insights that I think are worth pointing out. nature.com/articles/s4158…
Excited to share this pre-print from my thesis work. I spent the past few years developing a model of diabetic neuropathy and unexpectedly found that macrophages infiltrate the nerves of diabetic mice and their recruitment is neuroprotective!! biorxiv.org/content/10.110…
Read this #EditorsPick from #PapersoftheWeek from @sarainthelab et al. and @Nature showing evidence that recruitment of macrophages into peripheral nerves delayed terminal sensory axon degeneration in a mouse model of diabetic peripheral neuropathy bit.ly/4b9GeLu #PRF
Macrophages protect against sensory axon loss in peripheral neuropathy @Nature @sarainthelab nature.com/articles/s4158…
So very proud of my ex-lab mate and forever friend, @sarainthelab! Her PhD paper is an extraordinary body of rigorous research which I believe will shape the field of peripheral neuropathy for years to come! nature.com/articles/s4158…
Nature research paper: Macrophages protect against sensory axon loss in peripheral neuropathy go.nature.com/42PD8u3
Featured as an #EditorsPick, at a look at this #PapersoftheWeek find from @sarainthelab and @NatImmunol reviewing the various immune drivers, like cytokines and endogenous opioids, impacting pain resolution and protection bit.ly/4fXmITP
Featured as an #EditorsPick, at a look at this #PapersoftheWeek find from @sarainthelab and @NatImmunol reviewing the various immune drivers, like cytokines and endogenous opioids, impacting pain resolution and protection bit.ly/4fXmITP
Beautiful paper by @sarainthelab @Aakanksha__Jain & Clifford J Woolf @BostonChildrens: Immune drivers of pain resolution and protection nature.com/articles/s4159…
Our latest paper details part of our unbiased, high-throughput screening efforts to uncover neuroprotective compounds against chemotherapy-induced degeneration on motor and sensory neurons. 4/1902 compounds worked across both neuronal subtypes. @PhRMA link.springer.com/article/10.100…
Guess who made it to the cover of @NatImmunol 🙋🏽♀️✨🥺
Check out our recent work @NatImmunol highlighting how every pain condition is different, and immune cells might hold the key to these differences. As a cherry on top, our DRG image was chosen as the cover art 😃 P.C. @sarainthelab nature.com/articles/s4159…
Check out our latest paper describing the neuro-immune signatures in distinct pain states. I’m very proud to have had the opportunity to contribute to this outstanding research and an invaluable resource for the pain community! nature.com/articles/s4159…
Finally did the thing and got that PhD 🥺🥳 🙏🏽 So grateful for my PI, amazing support system in lab, and my family!!! 💗
Immune drivers of physiological and pathological pain. A new Perspective from Aakanksha Jain (@Aakanksha__Jain), Sara Hakim (@sarainthelab), and Clifford J. Woolf @BostonChildrens: hubs.la/Q02sSn0j0 #InnateImmunity #inflammation #Neuroscience #Neuroinflammation
We are delighted to share our latest study published in science translational medicine! Nociceptor spontaneous activity is responsible for fragmenting non–rapid eye movement sleep in mouse models of neuropathic pain | Science Translational Medicine science.org/doi/10.1126/sc…