Debolina Ganguly

Thrilled and honored to be a named a Parker Scholar! Very excited to be a part of the PICI network. Grateful for the support of my incredible mentor @JudithAgudo1 and the PICI leadership @DanaFarber

With Pravat starting his lab @IISER and Kangsan joining @AstraZeneca as Senior scientist, we are looking for aspiring #postdocs to join us. Please reach out if you are interested in studying and developing strategies to prevent #metastasis !! Please RT shorturl.at/isQY6 1/2

Stellar postdoc ⁦@DebolinaGanguly⁩ and I wrote this spotlight in for a super cool paper on the systemic effects of metatasis in breast cancer. The organ of metastatic disease has a BIG impact! Highly recommended paper in ⁦@Cancer_Cell⁩ secure-web.cisco.com/1be_LDSMLB9GnZ…

1/ 🚨 Hot off the press in @NatImmunol: CD4⁺ T cells can license Kupffer cells to rescue dysfunctional CD8⁺ T cells in the liver. Hepatitis B virus (HBV) infection is just the proving ground—this is a paradigm shift in tissue immunity. nature.com/articles/s4159… 🧵(1/11) 2/…

#UTSW biochemist Zhijian "James" Chen, Ph.D., wins the Albert Lasker Basic Medical Research Award, sometimes called “America’s Nobel,” for his discovery of the cGAS enzyme, which senses invading pathogens and triggers immune response. bit.ly/3MQjHIr @LaskerFDN

Debolina Ganguly, PhD (@debog93), a 2024 Parker Scholar at @DanaFarber, studies how metastatic stem cells promote systemic tolerance to tumor antigens & suppress responses to immunotherapy, advancing understanding of patient response. Hear more about PICI’s support of her work.

So proud of @debog93 for receiving this prestigious fellowship from @parkerici to discover how to make breast cancer responsive to immunotherapy. World, get ready, a new super star is rising!

Best Bday gift ever! Happy bday to me!🤩 collaboration with gut stem cell super expert ⁦@ohyilmaz⁩ to find how immunogenic Lgr5 cells can grow into tumors and evade immune surveillance. Team work makes the dream work (and the fun work!) nature.com/articles/s4158…

open access link to our paper. We prove: 1. immune cells can prevent cancer, and 2. Mutated cells must turn immune silent to grow cancer, here with a fetal reprogramming. With gut stem cell expert ⁦@ohyilmaz⁩ and me as the immune evasion expert secure-web.cisco.com/1BU72ZRw5WM4am…

“Ten years ago I was kicked out and forced to retire.” Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges. Ten years ago, Karikó was still doing all her…

Had a wonderful time yesterday at UTSW graduation ceremony! It was great meeting @brekkenlab @BrekkenDeirdre @Sorrell_Lab @MalladiLab and everyone else! So grateful for the training that I received here @UTSWCancerBio @UTSWGradSchool

@UTSWCancerBio grads!, well some of them, @debog93 @dbezwada

Recruiting postdocs interested in immune evasion and #breastcancer . Experience in cloning/cell engineering and in vivo mouse work are a plus! See the type of work we do😊 cell.com/cell/pdf/S0092…

A great joint journal club discussing complex issue in #breastcancer #immunology with powerhouse labs @SandraMcAllist4 @JudithAgudo1 @vangalenlab @EMittendorfMD. Only screenshot I got...we are deep in thought! @DFCI_BreastOnc @BrighamSurgery

Pleiotrophin drives a prometastatic immune niche in #BreastCancer, say Debolina Ganguly @debog93, Rolf Brekken @brekkenlab et al @utswcancer @UTSWNews: bit.ly/3IRSdB9 @gilbertzmurimwa @FaValdesMora @dgallegoortega #TumorImmunology #metastasis

.@debog93 @brekkenlab et al @utswcancer find that metastatic #BreastCancer cells thrive in secondary organs by producing pleiotrophin & activating the NF-κB pathway, leading to increased cytokine production, neutrophil recruitment, and T cell dysfunction. bit.ly/3IRSdB9

Excited to share that I have started my post doc in the @JudithAgudo1 lab!! Had my first brainstorming session today and I am super pumped! #newpostdoc

Signing off from utsw! Thank you everyone at utsw for making my PhD so memorable!