danny
@danny_nkjg
ai x bio @chaidiscovery | z fellow | prev: mech interp, farming in florida (??), alps, physics, berkeley
I'm super excited to be able to finally share this breakthrough with everyone!! It's been a true honor to be able to work on this project with my incredible teammates, and I can't wait to watch how Chai-2 transforms this space! You better believe we're only getting started 😎😎
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
I would LOVE to see what Gödel would have cooked up if he lived in the era of mature programming languages
🎉 Congratulations to @ZhuoranQ for winning the Chen Institute and @ScienceMagazine AI Prize, recognizing his groundbreaking AI research in biochemistry. We’re honored to have him on the @chaidiscovery team!
Congratulations to the winners of the 2024 Chen Institute and @ScienceMagazine AI Prize! Winners share $50,000 in cash awards and their research essays will be published in Science. Learn more about grand prize winner @ZhuoranQ and finalists @Roobaert_Alizee and @neuronair here:…
Zero-shot antibody design in a 24-well plate @chaidiscovery 1. Researchers have introduced Chai-2, a multimodal generative model that marks a significant leap in de novo antibody and miniprotein design. This platform achieves an impressive 16% hit rate in de novo antibody…
Some use cases are cooler than others, and it's safe to say zero-shot antibody design is one of them. Congrats on launching Chai-2!🧬
Big thank you to stellar engineering team at @modal_labs, who provided some critical infrastructure for this effort. They are a joy to work with.
Introducing Chai-2 - foundation model enabling low-N de novo antibody design. We experimentally validated Chai-2 on 50+ targets, >15% binding success rate - exceeding what a lab could previously achieve. Looking forward to scaling these progresses to the entire proteome.
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
It takes true inventiveness to break ground. This is pioneering work! And it makes me so happy to see Josh’s life’s work coming to life. Congratulations @joshim5, @_jackdent, @Mattmcpartlon1, @Kevin_E_Wu, @_nathanrollins, @j_boitreaud, @danny_nkjg, @ZhuoranQ, @pwolle_ & Alex!
I've been working on variants of this problem for my entire career, and have only dreamed of designing molecules on the computer with success rates this high. Proud of @chaidiscovery for pulling this off, and doing it with the speed, rigor and grace that was only imaginable ✨
It's been a privilege work alongside the most uniquely talented group of individuals I've ever encountered on this breakthrough result @Kevin_E_Wu, @_nathanrollins, @j_boitreaud, @danny_nkjg, @_jackdent , @joshim5, @ZhuoranQ and others. You all made this possible!
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
We’re excited to introduce Chai-2, a major breakthrough in molecular design. Chai-2 enables zero-shot antibody discovery in a 24-well plate, exceeding previous SOTA by >100x. Thread👇
Beginning to suspect that “introversion” is a proxy for the severity of one’s trust issues towards the rest of the world
We're excited to partner with the UK Government on OpenBind, an effort to create the largest open dataset of drug-protein interactions in history. More data → smarter AI models → better medicines gov.uk/government/new…
Please for the love of god tell me ppl are vibe coding algoraves with tidal + cursor. If this isn’t happening yet so help me god im joining the algorave scene
Our interpretability team recently released research that traced the thoughts of a large language model. Now we’re open-sourcing the method. Researchers can generate “attribution graphs” like those in our study, and explore them interactively.
If you set up codex right, you literally have a virtual organization. Like actually