Sabine D. Brookman-May
@brookmans76
Professor of Urology @LMU_Muenchen, SVP Therapeutic Area Head Urologic Oncology @AuraBiosciences - former VP R&D J&J - Sports Medicine 🚵♀️Passionate Cyclist
📢 The EA8212 “BRIDGE” study will officially close to accrual on July 24. If you have patients interested they will need to be randomized by then 👏 Huge thanks to all investigators—& especially patients—for helping enroll nearly 900 participants in just 2.5 years. @eaonc
Longer follow up for Enfortumab Vedotin & Pembro in urothelial cancer @Annals_Oncology shows mOS at nearly 3 yrs (34 mnths) with 50% of responses (68%) continuing at 2 years! Experience in tox management is important. Duration of therapy uncertain in CR gbr01.safelinks.protection.outlook.com/?url=https%3A%…
Consistent & practice-changing! Talazoparib + Enzalutamide improves OS in HRR-deficient mCRPC. OS: 45.1 vs 31.1 months (HR 0.62). BRCA1/2+: 4-year OS 53% vs 23%. A new SoC is here. @asco @oncoalert #prostatecancer #oncology @neerajaiims @CParkMD @TheLancet @APCCC_Lugano @Larvol…
Excited to share our newest paper on digital pathology AI biomarkers in prostate cancer RT. In this work we: ▶️performed a systematic review ▶️checked ongoing trials ▶️collected an expert consensus sciencedirect.com/science/articl… Thanks @RO_GreenJournal for accepting this work
Thank you for organizing and leading! This is an exciting area in oncology. More big things to come
Got my new bike Last Friday 🤩🤩🤩 And love it ❤️ #Roadbike #Wilier Filante SLR - today cycling in the rain, which was quite refreshing 🚴♂️🚴♂️🚴♂️
Sending a few pictures from the last couple of weeks on the bike - great rides here, sometimes hot 🔥, now more rainy and windy again, but beautiful 🤩 #Roadbike #Cycling #Bavaria 🚴♀️🚴♀️🚴♀️
It’s not just a grant/project that is canceled. This approach does not simply redirect our great scientists to something else. We derail their careers. We threaten scientific progress. And the next gen of scientists is cut at the roots. Incredibly short sighted 😞
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Please join us in congratulating @HsiehLab of @FredHutch for this 2025 Bladder Cancer Research Innovation Award. Dr. Hsieh’s research aims to uncover how mutations in other commonly altered genes contribute to diversity in BC. Click here to learn more: bcan.org/bcan-awards-60…
Going to bed earlier than usual led to more movement the next day. 💤 Sleep well, 🏃♂️🏃♀️ move more. They work better together. #Sleep #Exercise @PNASNews @OncoAlert doi.org/10.1073/pnas.2…
Had a great #Cycling tour 🚴♀️🚴♀️🚴♀️ in Northern Bavaria #Rhön ahead of my 30th Abitur Anniversary #Roadbike - and recognized I am definitely fitter now thank 30 years ago 😁💪
🧬 Can life begin with just two sperm cells? 🐭In mice it did. Healthy, fertile offspring, made with only paternal DNA. 👀 Could this change how we think about family, birth, and ethics??? some many question........ #Epigenetics #CRISPR #Reproduction #Science @PNASNews…
Another hint that #BodyComposition - lean body mass - is more important than #BMI or BSA ✅ Here used for optimal dosing ➡️ side effects⬇️, #QoL⬆️ 👉Let,s consider it also more for other #cancer related outcome, diagnosis, treatment related aspects @oncodaily
Lean body mass–based oxaliplatin dosing reduces peripheral neuropathy in stage III colon cancer without compromising survival! ✅ Lower rates of grade ≥2 oxaliplatin-induced peripheral neuropathy ✅ Better quality of life ✅ No impact on relapse-free survival or overall survival…
Excellent short summary @IvoSchootsNL @ProfPadhani. MRI already funded and standard of care in Australia, UK etc, yet the vast majority of men in USA go straight to TRUS bx if PSA raised as MRI not uniformly funded. Can we change this? @dr_coops @daviesbj @uroegg @urogeek
Viewpoint: Prostate cancer screening is shifting toward a more beneficial and less harmful approach by using MRI-targeted strategies, which reduce unnecessary biopsies and overdiagnosis. ja.ma/45rVOSb @IvoSchootsNL
Excellent Review on PSMA PET for Prostate Cancer Diagnosis - Sabine D. Brookman-May (@brookmans76) @EUplatinum oncodaily.com/science/psma-p… #OncoDaily #Oncology #Cancer #Health #Medicine #MedTwitter #MedEd #MedOnc #MedNews #PSMAPET #ProstateCancer @CancerWorldmag
Excellent comprehensive review + metaanalysis on the diagnostic role of #PSMA Pet in #ProstateCancer ✅ High diagnostic value of PSMA PET, especially when combined with #MRI ✅ NPV indicates limitations to guide LND - not enough to omit biopsy @EUplatinum @oncodaily @elio_mazzone
🚨New in @EUPlatinum! 📌 PSMA PET for Prostate Cancer Diagnosis & Staging by @elio_mazzone et al 🧠 This comprehensive meta-analysis confirms the high diagnostic value of PSMA PET—especially when combined with MRI—but reminds us it’s not enough to skip biopsy or lymph node…
Just a reminder that it is #MensHealth week #Cancer #MentalHealth #HeartDisease #Lifestyle @oncodaily @Uroweb
Beautiful weather today in #Austria #Zillertal for cycling after rain and hail yesterday #Roadbike #Cycling #Alps
Avelumab’s survival impact in diabetic vs non-diabetic #BladderCancer patients. @shilpaonc @ClevelandClinic sits down with @UroDocAsh @MDAndersonNews to discuss the #JAVELIN trial and its impact on bladder cancer treatment. #WatchNow on UroToday > bit.ly/43jj0AV