AutophagyUK Network
@autophagyuk
UK-based community of autophagy researchers. Run an annual meeting where early & established scientists get together to share results, approaches and ideas.
Fantastic to have led this interesting work on the regulation of PINK by ISR with Pawan, @IlariaVolpi314 @miratul_neuro and see this online. Great teamwork and collaborators @LeaPwilhelm @LabGanley @GlennMasson @Rousseau_Lab @mrcppu. Please check it out!
Out Now! Updated story on #HRI kinase as a negative regulator of #PINK1 mitophagy. We now show that the small molecule ISR inhibitor #ISRIB boosts PINK1 activation. Collaboration with @LabGanley @Rousseau_Lab @mrcppu & @GlennMasson Click here for paper shorturl.at/G0IzL
Join us in Lorne for the 11th ISA. We have a fantastic line up of speakers at a beautiful coastal location in Australia. Hope to see you there!
Michael Lazarou and I will be chairing the 11th International Symposium on Autophagy (ISA) in Australia from 16-20 Nov 2025! 📍 Location: Lorne, Victoria, Australia 🌐 Register now: isa11.org Join us for five inspiring days of cutting-edge autophagy research!
Great stuff from the @martens_sascha lab. Explains much about selective autophagy cargo - machinery recruitment.
🚨 New paper alert from @martenssascha!🚨 We explore how transmembrane cargo receptors initiate selective autophagy. Through biochemical reconstitutions, we discover a new autophagosome biogenesis pathway with implications for therapeutic interventions. biorxiv.org/content/10.110…
Functional relationship between lysosomal properties. From a Perspective by Néel et al. @IGF_Montpellier reviewing the role of the endolysosomal system in conventional & unconventional protein #secretion hubs.la/Q02KYw420 #trafficking #endosomes #lysosomes
"🅴🅼🅴🆁🅶🅸🅽🅶 🆁🅾🅻🅴🆂 🅾🅵 🅰🆄🆃🅾🅿🅷🅰🅶🆈 🅵🆁🅾🅼 🅲🅴🅻🅻🆂 🆃🅾 🅾🆁🅶🅰🅽🅸🆂🅼". September, 12-13, 2025, Department of Fundamental Neurosciences (Lausanne). Anna Simonsen (NO) and Katja Simln (UK). meetings.ls2.ch/autophagy-work…
Excited to share that our chapter in the book 'ATG8ylation and Its Manifestations' is now published, co-authored with @TimSargeant1 ! Big thanks to @vpderetic for the opportunity to contribute to this work! cambridgescholars.com/product/978-1-…
SUBMIT YOUR ABSTRACT for 5th Annual Symposium Webinar on 28th and 29th October, 2024. Deadline 13 September, 2024. forms.office.com/r/3LE3cL1Hc0
Save the date!!! "Autophagy across scales" Don't miss EMBO Workshop. 27-28 September 2024 in Sorrento (Italy). For details: meetings.embo.org/event/24-autop…
SUBMIT YOUR ABSTRACT for 5th Annual Symposium Webinar on 28th October, 2024. Deadline 13 September, 2024. forms.office.com/r/3LE3cL1Hc0
Many congratulations from everyone @autophagyuk -
Gratulere til vår eminente forsker @TerjeJohansen17 med Kong Olav Vs kreftforeningspris for 2024 👏 Prisen får han for fremdragende innsats. – En enorm, litt overveldende ære, for meg og for forskningsgruppen min, sier han. kreftforeningen.no/aktuelt/vi-hed… Foto: #Kreftforeningen
Congratulations to everyone on the publication of this great new paper from @VIKorolchuk and colleagues
My life in Newcastle was always with mitophagy. Thrilled to share this story published @Dev_Cell illustrating mitophagy as an anti-ageing programme in human cells. Amazing collaborations with George Kelly and other lab members @VIKorolchuk. Enjoy!!! cell.com/developmental-…
Different ER–plasma membrane tethers play opposing roles in autophagy of the cortical ER | PNAS pnas.org/doi/10.1073/pn…
Excited to share our work out today at @Nature. We built on the proximity labeling technique to establish PhagoPL, a novel tool to study the protein composition of phagosome containing real and intact microbes! link.springer.com/10.1038/s41586…
Eat less to live longer? #Autophagy degrades damaged or toxic cellular material to keep cells in good shape. We discovered how #ATG16L1 shapes phagophores. Our article was published today in @NatureSMB ! thanks to all the authors !! Check it out: nature.com/articles/s4159…
Version of record In @eLife: Syntaxin 17 recruitment to mature autophagosomes is temporally regulated by PI4P accumulation doi.org/10.7554/eLife.…
We are looking for a Senior Scientific Officer to join our Transgenic Technologies lab, supporting state-of-the-art creation of genetically engineered in vivo cancer models deigned for discovery research 📅Applications close: 14 June 2024 🔗Apply here: crukscotlandinstitute.ac.uk/careers/scient…
Model of the regulation of autophagosome biogenesis by AMPK. @BarnabaCarlo, @DavidGBroadbent, @jenscs83 et al. clarify AMPKs regulatory role in #autophagy and highlight its potential as a therapeutic target to reduce autophagy. hubs.la/Q02y6LsL0 #CellMetabolism #Cancer
CONFLICT RESOLUTION!!! Have you ever had professional conflicts? This workshop will allow you to acquire skills to resolve conflicts at work. Register for October 2, 2024. #Don't forget to register, you will be able to work peacefully without conflicts#
Our perspective article in Neural Regeneration Research journal with Laetitia Aubry and @Tim_Barrett2 on mitochondrial and MAM dysfunction in #raredisease #WolframSyndrome, based on our research paper in Stem Cell Reports…thanks to @IcgsUob @lifearc1 journals.lww.com/nrronline/cita…
🆕 | Paper by @TCDA_CRUKBI and colleagues at KU Leuven shows that phosphorylation status of LRRK2 is important for its role in regulating autophagy in cancer and Parkinson's. nature.com/articles/s4141…