Evan Worden
@WordenEvan
Assistant Professor at the @VAInstitute working on chromatin and gene regulation.
Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. msft.it/6010S7T8n
Congratulations to VAI's Dr. H. Josh Jang, who has been appointed to assistant professor in our Department of Cell Biology. vai.org/article/van-an…
Happy to share great work my postdoc Hemendra Panwar. By complete serendipity, he determined several structures of the native metazoan H/ACA snoRNP, explaining how contacts within the snoRNP regulate Pseudo-U deposition. Great collaboration with @UteKothe. tinyurl.com/hrw2y9j4
Pleased to present our first preprint on how de novo DNA methylation occurs in di-nucleosomes. Lots of surprising findings about the linker length dependence of DNMT3 binding and activity. A great collaboration with the Peter Jones lab @VAInstitute. tinyurl.com/47pmv7hy
Congratulations to Dr. @BurtonNick, who earned a $2.9 million New Innovator Award from @NIH_CommonFund to find new ways to fix or prevent insulin resistance, a key driver of Type 2 #diabetes. #NIHHighRisk vai.org/new-innovator-…
Worden lab is excited for the Penn State Chomatin conference!
The @VAInstitute has an open faculty position in Structural Biology. Come join our vibrant research institute in Grand Rapids, MI and enjoy fantastic colleagues and support! Our search is open rank so please share with everyone, new or established! tinyurl.com/5a5uzh6u
Human mRNAs form globules in 3D and are prepared for export by the transcription-export complex. We are excited to share this and more mechanistic insights in our newest work, co-lead by the fantastic @bpachecofiallos and @MVorlandr. rdcu.be/c9e0f (1/9)
I would like to share with you our new work on the identification of the first bona fide 'reader' of #histone H3K79 methylation, which has been a mystery since the discovery of this modification in 2002. science.org/doi/10.1126/sc… today online in @ScienceMagazine
Chromatin was a liquid crystal the whole time - got it. nature.com/articles/s4146…
Today I learned (again) that you could be breaking US laws for: - Mentoring a graduate student - Hosting a visiting scholar - Sending research materials to a colleague - Traveling to a foreign country Wonderful...
So glad to represent @VAInstitute at @sacnas. I had a great time hearing from so many promising scientists. See you next year!
Always nice when you get some unexpected swag from your work! @VAInstitute
Come join VAI for your postdoc! We are committed to giving our postdocs great support, starting with a salary floor of ~70k/yr! There are several open positions at VAI, and you can apply to my lab below. jobs.silkroad.com/vai/VAICareerS…
As part of our commitment to supporting and investing in postdoctoral trainees, Van Andel Institute is increasing #postdoc starting salaries to $70,000 a year. Read more: vai.org/postdoc-support
Happy to announce that the Worden Lab is officially funded by @NIGMS! We also still have openings in the lab for ambitious postdocs! Apply 👇 (or email me) to join a vibrant and VERY supportive environment @VAInstitute in beautiful Michigan. jobs.silkroad.com/vai/VAICareerS…
Very excited to share my first paper with the @CWolberger lab now online in @PNASNews! By combining cryo-EM, mass spec, and integrative modeling, we provide insight into the recognition of H2B-ubiquitinated nucleosomes by the MLL1-WRAD complex. pnas.org/doi/10.1073/pn…