Valerio Zerbi
@Valerio_Zerbi
Professor @unige_en, alumni @EPFL_en and @ETH_en. Neuroimaging, neurotechnology, brain stimulation and cell transplantation in Psychiatry
NEW PREPRINT FROM THE LAB📢📢: Locus Coeruleus firing patterns selectively modulate brain activity and dynamics! 3y in the making and this work is finally seeing light thanks to a fantastic teamwork! C Grimm, S Duss and @BohacekLab. Short thread ⬇️ biorxiv.org/content/10.110…
Big step forward for awake rodent fMRI! Congrats @ShihYYI, Martin and team!
1/ Six years in the making! Our preprint on SORDINO fMRI is out. We're sharing the raw data and sequence to facilitate brain-wide mapping in awake, behaving rodents. If this could be useful to your colleagues and friends, please help spread the word! biorxiv.org/content/10.110…
A tenured position for layer-fMRI researcher is available in Paris at NeuroSpin.
New paper! We introduce an efficient set of statistical features for fMRI time series (calibrated on mouse manipulation experiments and tested on mouse and human data): catchaMouse16. Paper: doi.org/10.52294/001c.… Code: github.com/DynamicsAndNeu…
Alam et al. develop a canonical time-series feature set for characterizing biologically informative dynamical patterns in fMRI: doi.org/10.52294/001c.… @bendfulcher @fMRI_today @mallarchkrvrty1 @OHBM
Will deep brain stimulation be rewired by light? Will we one day swap metal electrodes for a beam? Is this something predicted by Francis Crick in a 1979 Scientific American article? YEP. And now enter a new Science Advances paper by Jin and colleagues. They have introduced a…
Autism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state reduces this rigidity and relieves various autistic traits. @takamitsu_w nature.com/articles/s4159…
Congratulations to our Human Neural Circuitry team; bit.ly/4dEyX7Z publishes today in Science! This was the hardest challenge of my career, but one of the most rewarding, after years of rebuilding– & for myself, expanding my inpatient neuropsychiatry work to the service…
Check out our new review on the history and future of resting state fMRI 🧠 @restingstate @Nature nature.com/articles/s4158…
Stem cell therapy for Parkinson’s disease has entered a new era. Two @Nature studies demonstrate that pluripotent stem cell–derived dopamine neurons can survive, restore function, and potentially change the treatment paradigm for this neurodegenerative disease.
Not in my specific domain of expertise, but really “cool” and elegant work. Congrats @TJRyan_77 and team!
Excited to share our new study: "Cold memories control whole-body thermoregulatory responses" by @Andrea_MZamora, @Akaron0884 & team at @tcddublin, in collaboration with @lynchielydia & @DrChristineAnnD @RyanLabTCD @Nature nature.com/articles/s4158…
An analysis of 20 autism mouse models point to two subtypes: One displaying out-of-sync brain activity and impaired synaptic pathways, the other with too much synchrony and dysregulated immune pathways. By @callimcflurry thetransmitter.org/spectrum/too-m…
Our scientists with over 150 collaborators have released the largest functional map and wiring diagram of the brain to date – seven years in the making. Today’s 1.6 petabyte release marks a historic day for neuroscience. This moonshot milestone will further efforts towards…
How does the brain work? Scientists are closer to the answer with the largest wiring diagram and functional map of a mammalian brain to date. 🧵
💡Optogenetic stimulation of projection terminals is often thought to preferentially modulate downstream targets. In our recent fMRI study led by @LiMingHsu2, we compared cell body and terminal stimulations, showing that potential antidromic effects shouldn’t be overlooked.👇
Optogenetic stimulation of cell bodies or axonal terminals triggers similar brain-wide activation patterns
Online now: Single-cell spatial transcriptomic atlas of the whole mouse brain dlvr.it/TJjqTG
👉👉New paper alert from @LabLuthi ! Newly promoted Dr. Cherrad, with @GFoustoukos, @FernandezLmj and others combines stimulation of sensory neurons from the #vagus nerve with #sleep, #heartrate, temperature and #locuscoeruleus recordings @unil #FBM #Neuro
Vagal afferent activation induces a NREM-sleep-like state with brain-body cooling, but locus coeruleus activation biorxiv.org/content/10.110… #biorxiv_neursci
In this week’s @Nature, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n
Brava Francesca! Presenting for the first time her results on LC photometry-fMRI at an international conference #EMIM2025 🎙️ Always a special moment. More to come soon!
This goes straight in my teaching series slides
Visualizing Effective Connectivity in the Human Brain Preprint: biorxiv.org/content/10.110… Code: github.com/ComaRecoveryLa… YouTube video: youtu.be/V0hqs-noYNg Download video & figures: zenodo.org/records/149748… Led by #XanderAtalay & #TeoFecchio @MGH_CNTR @MGHMartinos @MGHNeuroICU
Proud of this work led by @Gozzi_Ale and Marco Pagani following 10y or r&d, massive multi-labs collaborations and lots, lots of scans. See the inspiring 🧵 below 👇🏼
Can we use brain scans to identify biologically distinct "autisms"? And If so, how? In our latest cross-species study 🐭👨we dive into these questions! Find out more here 👇👇 biorxiv.org/content/10.110… Thread below 🧵 1/n
1/6: We have various positions within my new lab at UC Irvine. We are looking for a Researcher (recruit.ap.uci.edu/JPF09209; equivalent to Research Assistant Professor), postdocs (recruit.ap.uci.edu/JPF09107), and Research Assistants (Specialist Series:, recruit.ap.uci.edu/JPF09109).
What a pleasure to be interviewed by science writer @d_a_robson, and what even greater pleasure to read his informative and visionary narrative in @BBC_Future ! bbc.com/future/article…