VLC Phage Hunters (@VLCphagehunters)

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VLC Phage Hunters@VLCphagehunters · Dec 11, 2023

¿Habéis visto ya el vídeo que Diario de una Científica ha hecho sobre el trabajo que realizamos en el #EnBiVirLab y en @evolving_spain? 🤯🥰 ¡¡¡Nos encanta!!! instagram.com/reel/C0rwlvOqQ…

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VLC Phage Hunters@VLCphagehunters · Jul 17

Learning from PhD projects of other colleagues from @i2sysbio at the 5th edition of the Early Career Researchers Seminar! 💪🏼😊 Very enriching!

VLCphagehunters's tweet image. Learning from PhD projects of other colleagues from @i2sysbio at the 5th edition of the Early Career Researchers Seminar! 💪🏼😊 Very enriching!

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Pilar Domingo-Calap@pilardomingoc · Jul 11

Phage therapy in a patient with prosthetic join infection in Spain! Another sucessful treatment from the #EnBiVir @VLCphagehunters @evolving_spain in collaboration with Dr. de la Villa Special mention @mire_bg and @marcocv1497 for the phage production! sciencedirect.com/science/articl…

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VLC Phage Hunters@VLCphagehunters · Jul 14

Today's pre-holiday lab meeting! Happy with the current progress and motivated to continue our research 😊💪🏼🙌🏼

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VLC Phage Hunters@VLCphagehunters · Jul 1

Disfrutando de nuestro retreat de lab celebrando la plaza de profesora titular de @pilardomingoc 🥰🙌🏼

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VLC Phage Hunters@VLCphagehunters · Jun 20

Otras alternativas terapéuticas como la fagoterapia en pacientes con enfermedad pulmonar por micobacterium abscessus. Gracias por vuestra ayuda! Muy agradecida 🙌🙌 #fagoterapia #mycobacteriumabscessus

VVLC Phage Hunters@VLCphagehunters · Jun 17

Our PhD researcher Mireia @mire_bg presenting today at 1st International Symposium on Advances in Phage Therapeutics @AzeredoLab the preliminary results of 4 compassionate phage use for M. Abscessus infections using a 6-weeks treatment approach including local administration 💪🏼😊

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Jérémy Dufloo@Jeremy_Dufloo · Jun 19

Thrilled to have been awarded a Ramon y Cajal 5-year tenure-track contract to continue working on viral entry (and more!) with @Rafa_Sanjuan_ at @i2sysbio and @UV_EG 🎉😃

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Graham Hatfull@GHatfull · Jun 19

Late-decision abstract submissions are open for Phage Biology, Dynamics, and Therapeutics: iasusa.org/bacteriophage-…

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VLC Phage Hunters@VLCphagehunters · Jun 19

Proud of our colleague from @Rafa_Sanjuan_’s lab @Jeremy_Dufloo who has been awarded a Ramon y Cajal contract from @CienciaGob 😊🙌🏼 well-deserved! 🥳 congrats! 💪🏼 @i2sysbio

JJérémy Dufloo@Jeremy_Dufloo · Jun 19

Thrilled to have been awarded a Ramon y Cajal 5-year tenure-track contract to continue working on viral entry (and more!) with @Rafa_Sanjuan_ at @i2sysbio and @UV_EG 🎉😃

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Mireia Bernabéu-Gimeno@mire_bg · Jun 18

Coming back from enriching 2-days with all our scientific colleagues from the phage therapy field 😊 honored to share the first results of compassionate treatments for M. Abscessus as part of my PhD project 💪🏼 Thanks @pilardomingoc and @AzeredoLab for the opportunity!

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VLC Phage Hunters@VLCphagehunters · Jun 18

Already available at @biorxivpreprint the results of one of the PhD projects from our colleague @LucasMQQQ 🥰 Valuable insights about K. pneumoniae phage-resistance mechanisms 🧫🙌🏼 Do not miss it! biorxiv.org/content/10.110… @pilardomingoc @Rafa_Sanjuan_

LLucasMQ@LucasMQQQ · Jun 18

📢 Very excited to share our latest work on K. pneumoniae resistance to phages! We show that phage resistance can occur through capsule loss in a fast and reversible way in the abscence of mutations! 🦠🧬 biorxiv.org/content/10.110… @pilardomingoc @Rafa_Sanjuan_ Thread here!🧵👇🏻

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LucasMQ@LucasMQQQ · Jun 18

Check out the full story 👉🏻 biorxiv.org/content/10.110… @VLCphagehunters #phage #Klebsiella #microbiology #capsule

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LucasMQ@LucasMQQQ · Jun 18

These findings suggest that Klebsiella can resist phages via changes in gene expression, offering a flexible and dynamic alternative to mutation-driven resistance. A new layer of complexity in phage-bacteria interactions!💡🌌

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LucasMQ@LucasMQQQ · Jun 18

Using single-cell assays, we found that once phage pressure was removed, these acapsular cells rapidly restored capsule production regaining sensitivity to phage. A fast and reversible response to phage selective pressure! 🦠🔁

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LucasMQ@LucasMQQQ · Jun 18

In our study, phage infection selected for acapsular variants without any detectable mutations. However, we observed a significant downregulation of capsule related genes via transcriptomics. A non-mutational route to resistance! 🔬📊

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LucasMQ@LucasMQQQ · Jun 18

Previous studies showed that Klebsiella evades phage infection by losing or modifying its capsule due to mutations in capsule biosynthesis genes 🧬

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LucasMQ@LucasMQQQ · Jun 18

📢 Very excited to share our latest work on K. pneumoniae resistance to phages! We show that phage resistance can occur through capsule loss in a fast and reversible way in the abscence of mutations! 🦠🧬 biorxiv.org/content/10.110… @pilardomingoc @Rafa_Sanjuan_ Thread here!🧵👇🏻

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VLC Phage Hunters@VLCphagehunters · Jun 17

Proud of @mire_bg presenting part of her PhD project treating M. abscessus-infected patients with #phage. Thanks to @AzeredoLab for the opportunity to present our work at the 1st Advances in Phage Therapeutics! @UV_EG @CSIC @VLCphagehunters @evolving_spain @FEFQ_CFspain

VVLC Phage Hunters@VLCphagehunters · Jun 17

Our PhD researcher Mireia @mire_bg presenting today at 1st International Symposium on Advances in Phage Therapeutics @AzeredoLab the preliminary results of 4 compassionate phage use for M. Abscessus infections using a 6-weeks treatment approach including local administration 💪🏼😊

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VLC Phage Hunters@VLCphagehunters · Jun 17

Our PhD researcher Mireia @mire_bg presenting today at 1st International Symposium on Advances in Phage Therapeutics @AzeredoLab the preliminary results of 4 compassionate phage use for M. Abscessus infections using a 6-weeks treatment approach including local administration 💪🏼😊

VLCphagehunters's tweet image. Our PhD researcher Mireia @mire_bg presenting today at 1st International Symposium on Advances in Phage Therapeutics @AzeredoLab the preliminary results of 4 compassionate phage use for M. Abscessus infections using a 6-weeks treatment approach including local administration 💪🏼😊

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Dr. Sabrina Green, PhD@MotherOfPhage · Jun 17

Mireia Bernabeu-Gimeno speaking in M. abscessus infections and phage therapy. Advances in #Phage Therapeutics

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VLC Phage Hunters@VLCphagehunters · Jun 16

Visit our poster P06 at the 1st International Symposium on Advances in Phage Therapy #Braga2025 @AzeredoLab about mycobacteriophages!! Proud of @marcocv1497 presenting part of his PhD project!! @UV_EG @CSIC @VLCphagehunters

VVLC Phage Hunters@VLCphagehunters · Jun 16

Come and visit our poster P06 during the poster sessions at 1st International Symposium on Advances in Phage Therapeutics @AzeredoLab 😊 Our colleague @marcocv1497 will be presenting our phage collection for M. Abscessus and all his work for expanding the host range!

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