Centre for Targeted Protein Degradation
@UoDCeTPD
The Centre for Targeted Protein Degradation is an academic research centre focussing on #TPD. Part of the School of @UoDLifeSciences @DundeeUni
Recruiting for a scientist with structural biology/biophysics expertise to join our KOODAC team for 12 months. Apply via dundee.ac.uk/work-for-us/jo… to join our team that use protein degradation strategies to target previously undruggable drivers of children's cancers.

Concluded my 3-year (fixed term) contract at @UoDCeTPD (CeTPD)/@UoDLifeSciences / @dundeeuni from spring 2022 to spring 2025. I could not really describe my job the last three years, but I got to do a lot. Providing #StructuralBiology expertise, recombinant proteins, and…
The April–May CeTPD Journal Club is out! Catch up on cool new #TPD papers. Thanks Alejandro, Giulia, Mhairi & Ryan! @UoDLifeSciences sites.dundee.ac.uk/alessio-ciulli…

Nice to have some visitors here in London @BirkbeckUoL Valentina and Liam from @UoDCeTPD 🏴, and UCL #NMR 🧲 facility manger @KevinHaubrich1. Had a quick peak at our ❄️🔬 #cryoEM abilities @ismb_london between users.
Protein degraders - Alessio Ciulli (@alessiociulli) Prof @Dundeeuni @UoDCeTPD shares new insights and twists of molecular mechanism and drug design at #TETSymp. View the full program and register at bit.ly/TETR2025
Congratulations to all the newly elected Fellows of the @royalsociety 👏Yasmine Belkaid, @institutpasteur 👏Zhijian (James) Chen, @UTSWMedCenter @HHMINEWS 👏@alessiociulli, @dundeeuni @UoDCeTPD Read the full list: 🔗 royalsociety.org/news/2025/05/n…
Tune in this Thursday for two great #TPD talks: 1) Maria Rodriguez-Rios & Conner Craigon @dundeeuni @UoDCeTPD will discuss BromoCatch 2) Mark Mabanglo & Mahmoud Noureldin @OICR_news will present DCAF1-PROTAC-WDR5 structures 👉Join us on May 29th at 12 PM EST/ 6 pm CET
We are honoured to announce that our Director Professor @alessiociulli has been elected a Fellow of the @royalsociety (FRS), one of the highest honours for any scientist. Full story: lnkd.in/eKvuNEWt

Join us on April 17th for an exciting double seminar from the University of Dundee @UoDCeTPD: @CharlCrowe on "Mechanisms of degrader-targeted protein ubiquitinability" and @ales_salerno on "FerroTACs." Details: …afarbertargetedproteindegradation.org
Feel happy and privileged to be here in Darwin Australia to learn about the exciting science going on everything chemical biology and medicinal chemistry at the @RACInational #MCCB2025 and sharing the latest work from our group @UoDCeTPD @UoDLifeSciences
The #MCCB2025 conference in Darwin kicks off in style, with @alessiociulli delivering an amazing talk on dual ligase targeting molecular glues, and their new bromocatch tag (Talk so good it blew the power out all across Darwin for a minute 😂)
The Feb-March Journal Club edition is finally here!! Thanks to our amazing editors: @justgiorgia, Angus, Gajanan and Stefan. Read to catch up with the latest literature in TPD! #openaccess #TPD #journalclub @UoDLifeSciences sites.dundee.ac.uk/alessio-ciulli…

I am delighted to share the story that we've been crafting at the @UoDCeTPD in collaboration with @Tocris @biotechne for the last to years! We're thrilled to present BromoCatch - a self-labeling tag platform for protein analysis and manipulation. biorxiv.org/content/10.110…
Thank you @BiochemSoc! We are honoured to receive this award. It highlights the importance of team science and partnership working.
Congratulations to ACBI PROTAC collaboration team, winners of the 2026 Industry and Academic Collaboration Award! Headed up by @alessiociulli, the trail-blazing collaboration with @Boehringer combines their world-class expertise in targeted protein degradation and drug discovery
Excited to share the Farnaby Group’s first pre-print, detailing our approach to plate-based bifunctional chemical probe discovery, identifying a brain active PROTAC directly from a single screen. 1/7 chemrxiv.org/engage/chemrxi…
Really inspiring visit and talk from @alessiociulli @UoDCeTPD in our #MolecularTherapeutics series at @UCBerkeley! It is amazing what you have built in Dundee, Alessio! @MTI_Berkeley @MTI_UCB
Happy International Day of Women and Girls in Science 2025 from CeTPD! 👩🔬 We're proud to carry out our science in a diverse and welcoming environment, and strive to promote equal access to science for women and girls at all career levels 🧬 #womeninscience #womeninSTEM #IDWGS

The Nov-Jan Journal Club edition is finally here! We have new features, including a section dedicated to papers from CeTPD. Thanks to our editors: @CharlCrowe, @Holmqvist89, Jon and @MariaRRios3 #openaccess #TPD #journalclub @UoDLifeSciences buff.ly/3EpmffB

A team from CeTPD have released an excellent review that examines patents involving VHL ligand and PROTAC modifications from 2019 to 2024. We hope this resource will help guide the creation of the next generation of VHL PROTACs. buff.ly/4aWKcY6 #openaccess #TPD

Congratulations to @ales_salerno from @UoDCeTPD and @tineisadora from @Stanford who have been selected as awardees of our conference travel scholarships to attend the Keystone Proximity-Based Therapeutics conference!