Farnaby Group
@FarnabyLab
Farnaby lab is on twitter now! We work on discovery of #molecularglues and #PROTACs to better understand and address CNS diseases. We are based in @UoDCeTPD and part of @UoDLifeSciences at @dundeeuni.
We are super excited to be part of this new partnership between @UoDCeTPD and @BioAscent , also supported by @innovateuk developing novel methods for high-throughput degrader synthesis and screening.
⭐️The KTP between @BioAscent and @dundeeuni is aiming to foster #innovation that will transform the drug development landscape. @IUK_KTP @innovateuk @IUK_Connect @UoDRIS
Highly recommend this post doc opportunity in the Mehta lab @mrcppu
Postdocs invited to apply to join an exciting project involving kinome-wide CRISPR screening in iPSC-derived motor neurons co-cultured with microglia to uncover novel targets for C9ORF72 motor neuron disease. #MND #ALS #CRISPR #neuron #postdoc Visit: shorturl.at/Do9yU
Excited to share our discovery of ACBI4: VHL PROTAC degrader of KRAS(on) mutant e.g. G12R. High ternary-complex cooperativity to the rescue! VHL Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-loaded KRAS(on) Alleles | ChemRxiv - go.shr.lc/4efUF2s
Check out the latest edition of the CeTPD journal club
The April–May CeTPD Journal Club is out! Catch up on cool new #TPD papers. Thanks Alejandro, Giulia, Mhairi & Ryan! @UoDLifeSciences sites.dundee.ac.uk/alessio-ciulli…
@FarnabyLab in the stage now @autophagyuk and @UK_proteostasis meeting
Day 1 of the UK #Autophagy and #Proteostasis Conference at @UoDLifeSciences with opening remarks from Prof Ian Ganley.
A privilege to be a part of @CancerGrand Team-KOODAC that is called out in this nice @Nature Feature by Ken Garber as a model for change in drugging hard-to-treat cancers in children. How protein-slayer drugs could beat some of the cruellest cancers nature.com/articles/d4158…
I am delighted to share the story that we've been crafting at the @UoDCeTPD in collaboration with @Tocris @biotechne for the last to years! We're thrilled to present BromoCatch - a self-labeling tag platform for protein analysis and manipulation. biorxiv.org/content/10.110…
Registration for the joint Autophagy UK & Proteostasis UK meeting is now open. Going to be a great meeting and we look forward to welcoming you to Dundee!
A team from CeTPD have released an excellent review that examines patents involving VHL ligand and PROTAC modifications from 2019 to 2024. We hope this resource will help guide the creation of the next generation of VHL PROTACs. buff.ly/4aWKcY6 #openaccess #TPD
We have a fully funded PhD position in the lab! Looking forward to finding excellent talents to work with! Deadline is 17th Jan! Check out the link for more information! dundee.ac.uk/phds/opportuni…
Couple more days left to apply for our PhD studentship with Promega...
@FarnabyLab, @promegauk have teamed up on a PhD studentship with co-supervision from Prof. Kevin Read of @DDU_Dundee. If you're interested in targeted protein degradation and would like to do a PhD at the world class @UoDCeTPD then take a look below.
@FarnabyLab, @promegauk have teamed up on a PhD studentship with co-supervision from Prof. Kevin Read of @DDU_Dundee. If you're interested in targeted protein degradation and would like to do a PhD at the world class @UoDCeTPD then take a look below.
Funded PhD studentship available to start in Sep '25 working as part of a collab between our lab @UoDCeTPD, Prof Kev Read @DDU_Dundee and @promega aiming to establish assays and design rules for induced proximity molecule efflux and brain penetration. sites.dundee.ac.uk/farnaby-group/…