UK Dementia Research Institute
@UKDRI
The UK’s leading research institute transforming the lives of people affected by neurodegenerative conditions. Principal funder: @The_MRC
⭐️The UK DRI exists to transform the lives of people affected by or at risk of neurodegenerative conditions.⭐️ Our vision is ‘healthy brain🧠ageing for all’. Our research will transform lives. We are the UK DRI. @The_MRC @alzheimerssoc @AlzResearchUK @lifearc1 @TheBHF…
A pleasure to welcome Rory Cellan-Jones to the UK DRI at Cardiff! 🏴 Rory has written a fantastic blog about his experience meeting discovery scientists developing the next generation of treatments for Parkinson's & other neurodegenerative conditions 👇 rorycellanjones.substack.com/p/dementia-res…

New research led by @ValentinaEPrice reveals machine learning can match traditional statistical methods in predicting Alzheimer's risk 🧬 The study is the first to test this on a large scale, with data from 41,000 people👉buff.ly/UYK34dl

☣️🐀 Pesticide exposure in rats changes epigenetic signatures in different brain regions! Latest paper from our fruitful collaboration with Emily Rocha and Tim Greenamyre, linking epigenetic signatures of exposure to toxicants to Parkinson's disease.: nature.com/articles/s4153…
Cells in key brain regions involved in Parkinson’s retain a ‘memory’ of pesticide exposure that disrupts gene expression🧬 Research by @sj_marzi & colleagues unlocks understanding of the mechanisms behind the role of pesticide exposure in Parkinson’s👉buff.ly/1F16eUB
Don't miss @marcaurelbusche discussing his recent work in the next installment of our 'Rethinking Neurodegeneration' webinar series! 🙌 🗓️Tomorrow, Thurs 24 July at 4-5pm (BST) Register for free👉lnkd.in/envnAyzx
🧠How do brain circuits fail in early Alzheimer's disease? 🧠 Join Dr @marcaurelbusche for the next research webinar in our 'Rethinking neurodegeneration' series, taking place 4-5pm (BST), Thurs 24 July 🗓️ During this fascinating talk and Q&A, Dr Busche will present…
How can we better understand the impact of genetics on Alzheimer's risk? We spoke to @HazelLRoberts about her role in IPMAR, a major UK DRI initiative that established 100 stem cell lines, capturing the effects of Alzheimer's risk genes👉buff.ly/xDH8PnT

Huge congratulations to @MootazSalman (BHF-UK DRI Centre for Vascular Dementia Research) who has been awarded the prestigious Geoffrey Brunswick prize for established researchers by @BritPharmSoc!👏 🎉 Read more 👉 buff.ly/mpXQBPj

Last week, we were delighted to welcome @WarinderSJuss to the UK DRI at Imperial. Researchers shared how we are building toward a future of prediction & prevention through analysing smart tech & breakthroughs in mechanistic discovery. Read more here👉buff.ly/8ZRSXFj



Join our London Network Centre on 18 July for a free, interactive day exploring the latest in dementia research. Whether you're a carer, student, researcher, or simply curious about dementia, this free event is open to all. Reserve your spot: eventbrite.co.uk/e/dementia-ope…
Pleased to be able to contribute to this huge international effort led by @RikOssenkoppele and colleagues @biofinder_study exploring tau PET in n=12,048 individuals *open access* paper here: nature.com/articles/s4159…
Latest @MRCLHA Insight 46 paper — TL/DR: midlife air pollution influences late life cognitive function. Full text @LancetLongevity authors.elsevier.com/sd/article/S26…
PSP is a rare & devastating neurodegenerative disease with no effective treatments. Now, scientists led by @TSpiresJones & Dr Claire Durrant have shown that tau spreads via synapses in PSP, providing a target that could lead to future therapeutics👉 buff.ly/EB9vnY8

Don't miss @UKDRI's research webinar with Dr Marc Aurel Busche exploring how brain circuits fail in early #Alzheimers - years before symptoms appear. Taking place Thu 24 July, 4-5pm (BST). Register for free: ukdri.ac.uk/events/rethink…
Delighted to welcome Mary Ogbuka Kenneth to the UK DRI! 🎉 Mary joins @CynthiaSandor4's lab (UK DRI at Imperial) to investigate the genetics of pain in Parkinson's disease, as part of @HDR_UK's Black Internship Programme 👏

I’m excited to speak at this UK DRI webinar “Rethinking Neurodegeneration” on 24 July, discussing cell type- and circuit-specific vulnerability in early Alzheimer’s. #Alzheimers #Neurodegeneration #UKDRI
🧠How do brain circuits fail in early Alzheimer's disease? 🧠 Join Dr @marcaurelbusche for the next research webinar in our 'Rethinking neurodegeneration' series, taking place 4-5pm (BST), Thurs 24 July 🗓️ During this fascinating talk and Q&A, Dr Busche will present…
New research shows everyday wearables can detect early signs of #ParkinsonsDisease more sensitively than standard clinical tools. Could this pave the way for cheaper, earlier diagnosis of #Parkinsons? @UKDRI @ImperialBrains @imperialcollege #PD imperial.ac.uk/news/266173/sm…
Smart watches can detect early Parkinson's brain changes more sensitively than established clinical scoring systems, research by @CynthiaSandor4 reveals⌚ This could make early diagnosis faster, easier & cheaper👉buff.ly/h7xaHWk

What is the link between rugby and dementia? A new study of 200 former players aged 30-61, led by Prof David Sharp & Dr Neil Graham, found no cases of early-onset dementia, although some of the group showed potential signs of neurodegeneration👉 buff.ly/JulcQyL

The Rajani Lab is hiring! We are looking for a postdoc to join us at @UKDRI @EdinburghUni to investigate neuronal activity and white matter changes in vascular dementia. Apply here 👇 bit.ly/44AFJHx
🧠How do brain circuits fail in early Alzheimer's disease? 🧠 Join Dr @marcaurelbusche for the next research webinar in our 'Rethinking neurodegeneration' series, taking place 4-5pm (BST), Thurs 24 July 🗓️ During this fascinating talk and Q&A, Dr Busche will present…