Xavier Lab
@TheXavierLab
Genes to functions. Microbiome in health & disease. Computational biology. Chemical biology. Innate & adaptive immunity. http://broadinstitute.org/xavier-lab
Online now a multicenter Crohn's Disease study of South Asian patients that explores environmental impacts on #CD, linking geography and immigrant status with disease presentation and serologic markers. linkinghub.elsevier.com/retrieve/pii/S… #crohnsdisease
Check out our recent work with John Rioux and the iGenoMed Consortium! Serum proteomic and metabolomic profiling in #IBD patients initiating vedolizumab identified pro-inflammatory analytes associated with treatment response. onlinelibrary.wiley.com/doi/10.1111/im…
Bacterial sphingolipids delivered by outer membrane vesicles persist within mammalian immune cells and promote IL-10 secretion via the mevalonate pathway cell.com/cell-host-micr… @TheXavierLab @cellhostmicrobe @ericmichbrown
🚨New paper with @TheXavierLab @ScienceMagazine on the critical role of 🔁neuroimmune crosstalk in immune defense in the gut! @GeneLayInst @MGBResearchNews @HarvardMed @BroadInstitute science.org/doi/10.1126/sc…
Out now in @Science! We and the @KuchrooLab described responses of enteric neurons to inflammatory cues during infection, showing that primary sensory neurons detect type 2 cytokines, balance neuropeptides, and influence site-specific immunity. science.org/doi/10.1126/sc…
Thrilled to share that Rebecca Cohen, one of our outstanding clinical research coordinators, will join the Johns Hopkins ScM program in Molecular Microbiology & Immunology. Congratulations, Rebecca — wishing you continued success in this exciting next chapter! @JohnsHopkinsSPH📚
🎉 Huge congrats to Joanna Atwater, one of our amazing clinical research coordinators, on her next big step — pursuing a DMD at Tufts University School of Dental Medicine! Wishing you all the best on this exciting journey! 🦷📚 #FutureDentist #TuftsDental
A big congratulations to Xavier lab member Felicia Houttuijn Bloemendaal who has been awarded a prestigious European Marie Sklodowska-Curie postdoctoral fellowship to support her work on characterizing enteric neurons in human disease!!
Join us for a hybrid Broad Discovery Series talk, "Introducing the immune system, and expanding its cancer-fighting potential," with @Lloyd_Bod on February 11 at 6 PM ET. Learn more and register: broadinstitute.swoogo.com/lloydbod
Check out the findings from a collaboration w/the Clardy Lab! “There is a story out there linking the #gut #microbiome with #depression, and this study takes it one step further, toward a real understanding of the molecular mechanisms behind the link." hms.harvard.edu/news/drawing-l…