Li Tang
@Tang_Lab_EPFL
#Immunoengineering for better therapies | Associate Prof. of BioE @EPFL | Associate Editor @ESMO_IOTECH | Co-founder of @LemanBiotech
Thrilled to share our back-to-back two Nature @Nature papers on the unexpected role of type 2 immunity against cancer. We found that interleukin 4 (Fc–IL-4), a type 2 cytokine, reinvigorates exhausted T cells to potentiate anticancer immunotherapy w/ @YugangGUO2 @RongFan8(1/11)
Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…
Excited to attend and speak at FOCIS 20225 next week! @Focis_FCE @focisimmunology #FOCIS #FOCIS2025 focisnet.org/meetings/focis…
The Yin-Yang of metabolic modulation for improving cancer immunotherapy - check our most recent review article on metabolic immunoengineering! Kudos to my former postdoc Bing Feng, now PI at Hangzhou Inst of Medicine, and PhD students Rongrong @RRLi11606739 and Weilin @Weiliin_L
Feng et al. discuss the metabolic characteristics of tumor-infiltrating lymphocytes and innovative metabolic immunoengineering approaches to improve cancer treatment outcomes @Tang_Lab_EPFL cell.com/cell-systems/f…
We are excited to kick off our Forces at Play: Molecular Mechanobiology Seminar Series with Dr. Cheng Zhu from the Georgia Institute of Technology on January 16th at 12pm EST. If you aren't already on our distribution list, please register below for the Zoom link!
Many congratulations to Michele! @Materials_EPFL @MicheleCeriotti
Congratulations to @MicheleCeriotti for delivering his E. Bright Wilson Prize Lecture on machine learning for chemistry at @HarvardCCB! chemistry.harvard.edu/news/michele-c… #chemtwitter
Interested in working with 🐸, 🐭, stem cells, or computational methods 🖥️ to delve into the unknowns of regeneration in our new lab? Looking forward to enthusiastic and ambitious applicants! PhD program applications open! 🔗 phd.tuebingen.mpg.de/14722/phdproje… Please RT! 🙌
Beautiful illustration of E-CAR T cell👍A new way to engineer CAR T cells. Congrats, Chenqi, Haopeng, and the team👏
Glad to share our new publication @ImmunityCP , reporting a new E-CAR that can form mature immunological synapse through phase separation. Paper link: authors.elsevier.com/a/1kATc_OR%7Ey…
Interested in #singlecell and #spatial #metabolomics ? Then book your calendar for December 10th! – Our online, free event will summarize major achievements of the field in 2024. #metabolism #omics #MALDI #EPFL With @Gio_Dangel0 lab we prepared a fantastic lineup. 🧵 1/5
#ScienceSaturday ❓ How can we enhance CAR-T cell activity against solid cancers? ➡️ In a recent study, Zhao et al transduced CAR-T to express IL-10, resulting in enhanced T-cell proliferation, effector function, mitochondrial capacity and antitumor activity in a variety of…
Heading to PEGS Europe. will share our recent discovery of IL-10 CAR-T cells to treat blood and solid cancers!
Attendee list preview for #PEGSEurope now available! pegsummiteurope.com/attendee-list More than 1500 attendees are expected in Barcelona for the "best #biologics technology meeting in Europe." Book by Friday and you can still save €400. #antibodies #proteinengineering #immunotherapy
Our new study published today @Nature uncovers that Transgelin 2 preserves T cell lipid metabolism and anti-tumor activity. Transgelin 2 is silenced in dysfunctional TILs, and restoring its expression enhances CAR-T cell therapy in #OvarianCancer 👇nature.com/articles/s4158…
Doing research in Surface and lnterface Science & Tribology, and want to join @Materials_EPFL @EPFL_en? Send your application by December 1st! All info here: epfl.ch/about/working/…
Are you looking for a Faculty Position in Surface and lnterface Science & Tribology? The School of Engineering and The School of Basic Sciences at @EPFL_en are hiring! Check out the job description for more details: epfl.ch/about/working/…
Exciting opportunity! Faculty Position of Metabolism at Tenure Track Assistant Professor level at EPFL. deadline is approaching. please spread the word. epfl.ch/about/working/…
An Fc–IL-4 fusion protein reprogrammed cellular metabolism in terminally exhausted T cells in tumors, leading to enhanced cellular survival, cytotoxicity, and antitumor immunity. Read our summary here 👇 bit.ly/3Yi9uLm @Tang_Lab_EPFL @YugangGUO2 @RongFan8 @GruppSteve