Ashley St. John Lab
@StJohnLab
St. John lab @DukeNUS studies immune responses to human pathogens and develops novel vaccination strategies. We love mast cells. Tweets by Ashley.
Did you know that the fetal immune system can protect from congenital infection before birth? -Proud to share our study identifying protective functions of #microglia, contrasting the harmful early influence of #monocytes and primitive macrophages to #zika virus infection.
Now online! Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection dlvr.it/TG7FfY
Excited to share our new #OpenAccess review: "Maternal IgE Influence on Fetal and Infant Health" led by Jozef. We discuss how maternal #IgE shapes fetal immunity and the shift to intrinsic early-life IgE production, with implications for #allergy onset. 👉 doi.org/10.1111/imr.70…
Little break from talks to visit Knossos Palace… finally spending time with @Zhijuan_JExpMed not on zoom!
authors.elsevier.com/sd/article/S19… So excited to share our work on placental changes across gestation. Activation of immune cells types in term placentas even before labor and a reduction in toleragenic cells. Congrats @BunmiOlaloye et al. @YalePediatrics @YaleMed
Happy to share our preprint assessing the body composition, in a South Asian population. Adiposity and lean muscle indices that associate with cardiometabolic risk factors and inflammatory mediators in a South Asian population medrxiv.org/content/10.110… @chandi2012 @dumni
Very proud moment 😊- the 1st paper of our lab has just been published: science.org/doi/10.1126/sc… This tour-de-force work was bravely headed by the fantastic @MaryemRadhouani, showing that #Eosinophils develop #InnateMemory upon skin #infection with implications for lung #allergy
I'm excited to share that my first-author PhD paper is now published in @SciImmunology! We showed that skin infection with S. aureus imprints bone marrow eosinophils to fuel lung allergy. 🔗link to the study: science.org/doi/10.1126/sc… Let’s dive in 🧵1/9
Awesome Power of Genetic Screening! Very honored to be part of this wonderful discovery—MFSD6 is an entry receptor for Enterovirus D68!
🚨 New paper in Nature! MFSD6 is an entry receptor for enterovirus D68. Proud to have contributed to this work, led by brilliant co-first authors Lauren Varanese & Lily Xu. Gratitude to Jan Carette, Wah Chiu, and co-authors including Carolyn Bertozzi. 👉 nature.com/articles/s4158…
📢 Delighted to introduce the 2025 Associate Editorial Board: @Casanova_Acebes @CNIOStopCancer, @DGateLab @ARC_Neuro, Elisa Oricchio @EPFL_en, Tim O’Sullivan @UCLA, Ashley St. John @StJohnLab @DukeNUS, and Tuoqi Wu @UTSWMedCenter. Welcome! 👉 hubs.la/Q036rYrw0
Save the date for #HCVFlavi2025, a joint Asia-Pacific meeting to be held October 13-16, 2025 in Singapore @dukenus! More info to come!
Assoc Prof Ashley St John and her team have found that foetuses can better fight infections in the womb than we thought. Read more about it at duke-nus.edu.sg/newshub/media-… 📸: Chinmay Mantri #DukeNUS #Research #InfectiousDiseases #MaternalHealth @StJohnLab
I finally decided to open a Blue Sky account for our lab and will try to share the same lab news and shared papers on both sites for now. Find us at @stjohnlab.bsky.social
Check out our review "Mechanisms and risk factors for perinatal #allergic disease", led by Jozef and with @Abhay_R_. I♥️ how he simplified the complexities of allergies at the #maternal/#fetal & maternal/#infant interface. Authors' link for full access: authors.elsevier.com/sd/article/S09…
Our third year fellow Dr. Farouk Farouk, mentored by Dr. Amy Pham, was recognized for one of the Neo Abstracts of Excellence by the ILPQC.
This special issue is a labor of love that's been over a year in the making. Many thanks to the authors who contributed and those living with Long Covid who sounded the alarm in the first place.
In this week's new special issue on #LongCovid, a collection of articles explores the latest frontiers in disease mechanisms, sex differences, emerging therapeutics, and other facets of this enigmatic condition. bit.ly/3YN1ktt
Introducing ✨Dr✨Sid Malhotra who defended his thesis today! 🍾 He’s made it past another step on the path to be a clinician scientist! He’s also a @SD_GHI Doctoral Scholar and plans to continue his #globalhealth projects before returning to med school. @smlhtr_
Check out our commentary "Evolving vaccine discovery and development pathways for emerging pathogens" @eBioMedicine @EngEongOoi authors.elsevier.com/sd/article/S23…
Calling all Singapore Immunologists! Join us this Wednesday evening for a spooky Halloween gathering—costumes encouraged! 🎃👻 Register now and bring your colleagues and friends for a frightfully fun night!
Registration closes today @ 3pm, 👻🎃forms.office.com/r/ir1dEtfrmP (if you're bringing along a guest, remember to register them too!)
It’s predicted to be a rainy weekend in Taipei! What better way to stay dry inside Sunday morning than soaking up the immunology in the #FIMSA2024 symposium organized by SgSI?
Attending the 9th Federation of Immunological Societies of Asia-Oceania Congress (#FIMSA2024) in Taiwan? Join us on Sunday morning for the SgSI session on Immunoregulation! We're proud to feature five exciting talks showcasing research from Singapore 🇸🇬. Don't miss it!
Postdoctoral fellowship in Singapore for applicants who are citizens from South East Asia countries.