Davide Ruggero
@RuggeroDavide
Great tools and tips for the field to study IRES-dependent translation. Beautiful dissection of true HOX IRES translation in developing embryos. Congrats to all @mbarnalab @KatLeppek!
A powerful toolbox to study IRES activity highlights the IRES-dependent translation of HOX mRNAs in a cell and tissue specific manner . embopress.org/doi/full/10.10…
Small-molecule RNA therapeutics to target prostate cancer dlvr.it/TKlCgV
Online Now: Ribosomal rebellion: When protein factories drive cancer progression dlvr.it/TKMDq7
Thanks Levi Gadye and Laura Kurtzman for the thoughtful and creative press release! @UCSF @UCSFCancer
“Zotatifin, as a bona-fide ‘translatome therapy’ that blocks the production of cancer-causing proteins, expands the landscape of drugs available for patients,” @DuyguKuzuoglu on latest research w/ @haognguyen @RuggeroDavide @kevansf @ucsf ucsf.edu/news/2025/03/4… #PCSM
And we couldn't make it without @PCFnews @pcarroll_ and Benioff Initiative for Prostate Cancer Research support! cell.com/cancer-cell/fu…
A tour de force in deciphering in action the intriguing dynamic composition of ribosomes in vivo. Beautiful work! Congrats to all @mbarnalab!
Very proud of my graduate students @adelefrancisxu and Zijian Zhang & key members of our lab and collaborators @GarryPNolan & Sharon Pitteri lfor the incredibly hard work to characterize subcellular ribosomes. science.org/doi/10.1126/sc…
Thanks Levi Gadye, for the wonderful and insightful highlight of our last publication! @UCSF ucsf.edu/news/2025/02/4…
Congrats @mbarnalab @travisclantz and Christine on this award and making progress on targeting ribosomes to increase protein synthesis!
Very grateful for the support from @pewhealth for this project and @travisclantz who is an amazing graduate student who is taking the lead on getting this project off the ground!
Congrats on this beautiful paper on another great link between lipid metabolism and translation control! @DeSiqueiraMK, @ClaudioVillanu, and team!
Excited to share our latest work in @CellReports highlighting a PPARγ-dependent remodeling of translation machinery in adipose progenitors. Amazing collab between our lab @ClaudioVillanu @YangLabUCLA and @LauraHulea @CellPressNews @uclaibp cell.com/cell-reports/f…
Amazing work on uncovering a new role for tRNAs in linking mRNA stability with codon-specific translation! Congrats @Mendell_lab and team!!
I’m thrilled to share this story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu! We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation. science.org/doi/10.1126/sc…
Amazing paper on specialized ribosomes and their roles in cancer immune response! Congrats @liamfaller and all team!
I’m thrilled to share this story from @Mendell_lab and Jan Erzberger labs, led by postdoc extraordinaire Xiaoqiang Zhu! We showed that in addition to their canonical decoding function, tRNAs play a key role in regulating mRNA stability during translation. science.org/doi/10.1126/sc…
Thanks @RNACanadaC2R2 for organizing an amazing RNA meeting!
Davide Ruggero characterized the structure of Myv 5’UTR and a key RNA binding protein that regulates its translation level by interacting with specific structural motifs. Cool work
Maria Barna (Stanford University) on “Ribosomes in Gene Regulation: Controlling the diversity of proteins made in specific cells, tissues and organisms” #RNACanadaARN
The crosstalk between metabolism and translation dlvr.it/TD1fbs
We are excited to have our m6A sensor technology featured on the cover of the latest issue of Nature Biotechnology. Congratulations again to first author @RNAloops and @TheHornerLab and @TheHolleyLab for their great contributions! nature.com/nbt/volumes/42…