Nicastro Lab
@NicastroLab
We use Cryo-ET to characterize protein function and spatial orientation | UTSW Department of Cell Biology
CONGRATS to @JustinePinskey @AmirrasoulTava1 @loonggui and the other authors: their Choanoflagellate flagella study is now out in eLife!😁 doi.org/10.7554/eLife.…

Now out in eLife! Three-dimensional flagella structures from animals’ closest unicellular relatives, the Choanoflagellates doi.org/10.7554/eLife.…. Thanks to @AmirrasoulTava1 and @loonggui for helping this across the finish line, and to our reviewers for their great comments!
Despite the state of the world right now, I'd like to share a sliver of joy in the form of a new preprint on cilia structures in choanoflagellates - a great example of what you can find when you, as Feynman said, "just look at the thing!" shorturl.at/chxT4 #teamtomo 🧵
We are in the news! UT Southwestern’s #NicastroLab, led by Drs. Nicastro, Zhang & Zhao, just unveiled the complete 3D structure of the once mysterious “radial spoke 3” in mouse motile cilia! See more at: utsouthwestern.edu/newsroom/artic…
🎉 Congrats to Yanhe, Kangkang, @AmirrasoulTava1, @loonggui & co-authors for revealing the atomic structure of RS3, a Giga-sized complex in motile cilia! A tour de force in #cryoET, #cryoEM,#proteomics & modeling. Out now in Nat Struct Mol Biol! doi.org/10.1038/s41594… @CellUtsw

WE'RE HIRING! We are looking for a postdoc interested in structural cell biology and cryo-ET. See the link and attached flyer for more information 😀

Congratulations to @loonggui, Evan, and the other authors: our #cryoET study of the #apicomplexan #parasite invasion machinery is out now! This was a wonderful collaboration with @reeselab1! 🧪🧫 nature.com/articles/s4146…. @UTSWNews @CellUtsw

Great Science 🧫 🧬🧪 Great Community @Zhu_Lab @MalladiLab @Allan_HPool @LenoraVolk @GammonLab @Transactivator @DanuserLab @HullemanLab @YunsunNam @Zhu_Lab @ZhenyuZhonglab @JaqamanLab @FiolkaLab @joshuagruber @KonopkaLab @LabKohler @bsabari @NicastroLab
Thankful that our collaborative paper was included in this collection. Featuring work from @NicastroLab, @LabVanni, @Rachid_Thiam, @HenneLab and others! Also thankful for such amazing friends & collaborators.
We’re pleased to present The Year in Cell Biology: 2022, our annual collection highlighting some of the most outstanding articles published in the past year in JCB. We hope you enjoy the collection and we welcome your feedback! bit.ly/3UxePJT #CellBio2022
The Department of Cell Biology is excited to announce the appointment of our new Chair, William Prinz, Ph.D. ! He holds the Virginia and Edward Linthicum Distinguished University Chair in Biomedical Science. Congratulations, Dr. Prinz! 📸: @Sorrell_Lab
WE'RE HIRING! We are looking for a post doc interested in structural biology and cryo-ET. See the flyer attached for more information😃

We are back after break with @NicastroLab in our #emergingtechniques #cryoET (r)evolution of #cilia ultra structure over last 20 years. #cilia2022 cryofib milling brings in even deeper insight to motors, mutations & more!
"UTSW researchers may have solved the long-standing mystery of the genesis of crystallized cholesterol..." Read more about the collaborative study involving @HenneLab & @NicastroLab @UTSWNews utsouthwestern.edu/ctplus/stories…