Heiko Lickert (@LickertHeiko)

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Heiko Lickert@LickertHeiko · Nov 25

Thrilled to share one of our biggest discoveries: “Inceptor binds to and directs insulin towards lysosomal degradation in beta cells”. doi.org/10.1038/s42255… A tremendous collaborative effort led by @JohannaSiehler, @BilekovaSara and other members of the @LickertHeiko lab.

LickertHeiko's tweet card. Nature Metabolism - The insulin inhibitory receptor (inceptor) is found to bind to insulin and to regulate insulin stores by directing proinsulin and insulin towards lysosomal degradation.

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Alexander Bartelt@BarteltLab · Jan 19

Today, we report that chronic intermittent fasting impairs beta-cell maturation & function in adolescent mice. Using scRNAseq, we delineated a maturation score for beta-cells. Long-term good if you're older, might be harmful if you are still developing! 👇 cell.com/cell-reports/f…

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Rahul Satija@satijalab · Apr 22

Our Single Cell Genomics Day - highlighting our favorite new sc/spatial methods - starts Friday at 10AM ET! The most common question we get: is this open to anyone? Yes! Talks are free and live-streamed (no registration required) on Youtube and satijalab.org/scgd

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Dong-Jiunn Jeffery Truong@Earthnut89 · Apr 9

doi.org/10.1016/j.cell… ENVLPE, our system for VLP-based delivery of gene editors, is now published in @CellCellPress. We showed efficient delivery of base- and prime-editors in primary T cells & in vivo retinal models. Congrats co-first-authors @geilinho & @niggles293T!

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CALL TO ACTIVISM@CalltoActivism · Mar 5

Trump made a HISTORIC blunder during his speech while bragging he canceled $8 million in funding to turn Mice “transgender.” The funding was for TRANSGENIC studies, where scientists introduce human disease cells like Alzheimer’s to study a cure. Unreal.

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Heiko Lickert@LickertHeiko · Mar 5

Final count down…registration ends tomorrow…

EEMBO Events@EMBOevents · Dec 19

Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 – 04 April 2025 in Sant Feliu de Guíxols (Girona), Spain 📜 Registration deadline: 14 February 2025 meetings.embo.org/event/25-liver… #EMBOliverPancreas

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FASEB@FASEBorg · Mar 5

In her compelling op-ed published @Suntimes, @SocDevBio President Dr. Carole LaBonne warns that rapid innovation may not be suitable for science—where careful methodology, peer review, and sustained funding are key. If rushed, it risks breaking the very foundation of scientific…

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Heiko Lickert@LickertHeiko · Mar 5

Final chance to register is tomorrow…

EEMBO Events@EMBOevents · Dec 19

Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 – 04 April 2025 in Sant Feliu de Guíxols (Girona), Spain 📜 Registration deadline: 14 February 2025 meetings.embo.org/event/25-liver… #EMBOliverPancreas

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Heiko Lickert@LickertHeiko · Mar 2

So true, Alfonso! Hope we soon wake up again from this nightmare….who voted for this crazyness?!

AAlfonso Martinez Arias@AMartinezArias · Mar 2

I went to the US in the late 1970s. I had heard so much about “America” and must say, it did live up to my expectations. I owe much to the US, not only my PhD. 🧵

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Heiko Lickert@LickertHeiko · Jan 23

Exciting new tool to make the most out of multimodal single-cell data from our friends and long-term collaborators of the @fabian_theis lab - check it out, it works beautifully and really makes sense out of your complex data! 👇👍😉

FFabian Theis@fabian_theis · Jan 22

1/ Excited to see moscot-tools.org published in @Nature! We scaled Optimal Transport (OT) in single-cell genomics & added multimodality together with spatiotemporal trajectory inference, finding exciting new biology in the pancreas! 🚀 Read at nature.com/articles/s4158…

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Heiko Lickert@LickertHeiko · Jan 21

Registration deadline is coming closer - make sure you do not miss this excellent EMBO workshop 😉

EEMBO Events@EMBOevents · Dec 19

Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 – 04 April 2025 in Sant Feliu de Guíxols (Girona), Spain 📜 Registration deadline: 14 February 2025 meetings.embo.org/event/25-liver… #EMBOliverPancreas

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Alexander Bartelt@BarteltLab · Jan 19

This collaborative project between @HelmholtzMunich, @TU_Muenchen, & @LMU_Muenchen was led by @LeonardoMatta, Peter Weber, & Suheda Erener - Big THX to @RohmMaria, @LickertHeiko et al. & the reviewers & editors @CellReports

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Heiko Lickert@LickertHeiko · Jan 19

Congratulations Alex, team and partners!

AAlexander Bartelt@BarteltLab · Jan 19

This collaborative project between @HelmholtzMunich, @TU_Muenchen, & @LMU_Muenchen was led by @LeonardoMatta, Peter Weber, & Suheda Erener - Big THX to @RohmMaria, @LickertHeiko et al. & the reviewers & editors @CellReports

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Nature Metabolism@NatMetabolism · Jan 3

RESEARCH | @JohannaSiehler,@BilekovaSara, @LickertHeiko et al. (@HelmholtzMunich): Inceptor (insulin inhibitory receptor) regulates #insulin stores by directing proinsulin and insulin towards lysosomal degradation. nature.com/articles/s4225…

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EMBO Events@EMBOevents · Dec 19

Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 – 04 April 2025 in Sant Feliu de Guíxols (Girona), Spain 📜 Registration deadline: 14 February 2025 meetings.embo.org/event/25-liver… #EMBOliverPancreas

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Heiko Lickert@LickertHeiko · Dec 19

My top highlight for 2025 - EMBO workshop in Saint Feliu - three exciting days of science crossing boundaries of liver & pancreas research! Co-organised by @CebolaLab @1jorgeferrer @VallierLab @LickertHeiko & Emma Anderson #livertwitter #islets #masld #diabetes

EEMBO Events@EMBOevents · Dec 19

Apply now for EMBO Workshop on Liver and pancreas in metabolic disease: from pathways to therapies 02 – 04 April 2025 in Sant Feliu de Guíxols (Girona), Spain 📜 Registration deadline: 14 February 2025 meetings.embo.org/event/25-liver… #EMBOliverPancreas

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Matthias Mann Lab@labs_mann · Dec 16

China clearly sees the potential of proteomics and is about to place a gigantic bet on it; multi-billion dollar and 30 years!!! All the better for the advancement of science and health. We contributed to the white paper out now in @Nature nature.com/articles/s4158…

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Nature Metabolism@NatMetabolism · Dec 15

Top altmetrics score 2024: #17🏆✨ @LickertHeiko (@HelmholtzMunich) and co-authors show that #inceptor (insulin inhibitory receptor) regulates #insulin stores by directing proinsulin and insulin towards lysosomal degradation. nature.com/articles/s4225…

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Heiko Lickert@LickertHeiko · Dec 16

Nice to see our recent paper from a few weeks back taking off! Thanks and preXmas present to @JohannaSiehler and @BilekovaSara and our great team and cooperators @xlinkx_pd @SpeierLab @aman_ansar and others not on X and bluesky.

NNature Metabolism@NatMetabolism · Dec 15

Top altmetrics score 2024: #17🏆✨ @LickertHeiko (@HelmholtzMunich) and co-authors show that #inceptor (insulin inhibitory receptor) regulates #insulin stores by directing proinsulin and insulin towards lysosomal degradation. nature.com/articles/s4225…

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Heiko Lickert@LickertHeiko · Apr 10, 2024

Spannend und aufregend, Expertenrunde im Bundestag. Der Dialog zwischen Forschern und Parlamentarier ist essentiell für die Weichenstellung im Standort Deutschland und wir bleiben im Dialog 😉

HHelmholtz Munich | @HelmholtzMunich@HelmholtzMunich · Apr 10, 2024

🔬Expert Hour im Bundestag zu Durchbrüchen bei #Adipositas & #Diabetes! In der Diskussion ging es um bahnbrechende #Forschung im Kampf gegen die Volkskrankheiten, Heilungschancen & innovative #Therapien. 👉Mehr: t1p.de/b5a1a #Gesundheit #Forschung #HelmholtzMunich

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Heiko Lickert@LickertHeiko · Dec 13

Cool new tool from Fabian‘s team- looks very useful!

FFabian Theis@fabian_theis · Dec 12

1/🚀 Excited to share RegVelo, our new computational model combining RNA velocity with gene regulatory network (GRN) dynamics to model cellular changes and predict in silico perturbations. Here's how it works and why it matters! 🧵👇 biorxiv.org/content/10.110…

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