Kyle Cranmer
@KyleCranmer
Director Data Science Institute @UWMadison @datascience_uw. EiC @MLSTjournal. Physics, stats/ML/AI, open science. same handle @sigmoid.social and bsky
Here are the slides from my talk at #NIPS2016 on machine learning & likelihood-free inference for particle physics dx.doi.org/10.6084/m9.fig…

Super excited 3 days at the CECAM workshop co-organized with @drGregBowman, Bettina! Protein dynamics is definitely shaping up to be the next big topic in AI for Science! Huge thanks to @cecamEvents, @datascience_uw @UWMadisonChem, @TCI_UW_Madison, Emma & amazing DSI staff!
This week the Data Science Institute is hosting the @cecamEvents Flagship Workshop on Biomolecular Dynamics in the Age of Machine Learning, organized by DSI affiliate @XuhuiHuangChem, @drGregBowman, & Bettina Keller @datascience_uw @UWMadisonChem cecam.org/workshop-detai…
New setting: hide AI-generated images in DuckDuckGo Our philosophy about AI features is “private, useful, and optional.” Our goal is to help you find what you’re looking for. You should decide for yourself how much AI you want in your life – or if you want any at all. (1/4)
Very happy to see @GoogleDeepMind step up here… it’s the right thing to do statnews.com/2025/07/21/cas…
A nice article by @anilananth on using AI to explore design spaces, find unexpected solutions, (re)discover symmetries, and propose new relationships featuring @yuqirose @MarioKrenn6240 and myself. Note AI ≠ LLMs in this piece. quantamagazine.org/ai-comes-up-wi…
Beautiful story from @QuantaMagazine quantamagazine.org/ai-comes-up-wi… Honored to be featured together with @MarioKrenn6240 @KyleCranmer
“If my students had tried to give me this thing, I would have said, ‘No, no, that’s ridiculous'." — @Caltech's Rana Adhikari on an AI's solution for increasing @LIGO's sensitivity, using PyTheus, an AI designed by @MarioKrenn6240's team. The solution turned out to be an inspired…
“If I promote myself out of coding, I become a project manager.. a project manager of a murder of AI crows”
"I use AI in a separate window. I don't enjoy Cursor or Windsurf, I can literally feel competence draining out of my fingers." @dhh, the legendary programmer and creator of Ruby on Rails has the most beautiful and philosophical idea about what AI takes away from programmers.
Thrilled to share the Community Alignment dataset -- the product of a massive collaborative effort with so many awesome folks. Can't wait to see the future research it unlocks!
Today we're releasing Community Alignment - the largest open-source dataset of human preferences for LLMs, containing ~200k comparisons from >3000 annotators in 5 countries / languages! There was a lot of research that went into this... 🧵
NeurIPS is pleased to officially endorse EurIPS, an independently-organized meeting taking place in Copenhagen this year, which will offer researchers an opportunity to additionally present their accepted NeurIPS work in Europe, concurrently with NeurIPS. Read more in our blog…
Construction on Morgridge Hall is nearly complete and we can’t wait to welcome students this fall! Take a look inside the final stages of construction and get a first glimpse at the some of stunning art that will be on display: cdis.wisc.edu/morgridge-hall…
How Genentech/Prescient Design use AI to design 3-100x better antibodies Genentech uses lab in a loop as an iterative approach for designing antibodies by marrying generative machine learning models, property predictors and data from in vitro experimentation. Thread👇 The…
Woah, that looks like a LOT of work!
While making some figures for SGI* this year, I made some "behind the scenes" footage of how they get made: youtube.com/playlist?list=… Basically a video extension of cs.cmu.edu/~kmcrane/faq.h… ("figures?") *SGI is a great program run by @JustinMSolomon & deserves more funding
Yesterday, I was on the Larry Meiller Show with host Lee Rayburn to talk about AI for an hour! It is so important that we have public media like @WPR to discuss the good and the bad of these important issues. @datascience_uw wpr.org/shows/larry-me…

Congratulations to @DaniloJRezende and Shakir Mohamed! This is how first learned about normalizing flows. Their paper on VAEs could/should have also gotten a nod.
#ICML2025 test of time award
This week the Data Science Institute is hosting the @cecamEvents Flagship Workshop on Biomolecular Dynamics in the Age of Machine Learning, organized by DSI affiliate @XuhuiHuangChem, @drGregBowman, & Bettina Keller @datascience_uw @UWMadisonChem cecam.org/workshop-detai…

Wow. Justice Sotomayor wrote a chilling dissent: “When the Executive publicly announces its intent to break the law, and then executes on that promise, it is the Judiciary's duty to check that lawlessness, not expedite it.” We should all be alarmed.
Announcing AI for Science at @NeurIPSConf 2025! Join us in discussing the reach and limits of AI for scientific discovery 🚀 📍 Workshop submission deadline: Aug 22 💡 Dataset proposal competition: more details coming soon! ✨ Amazing line up of speakers and panelists
Giorgio Parisi opening StatPhys29: AI resembles the heat engine in that the technology arrived before the theory.