Julia Zeitlinger (@[email protected])
@JuliaZeitlinger
Investigator at the Stowers Institute for Medical Research, interested in regulatory genomics in development and evolution.
Our work on "Evaluating the representational power of pre-trained DNA language models for regulatory genomics" led by @AmberZqt with help from @NiraliSomia & @stevenyuyy is finally published in Genome Biology! Check it out! genomebiology.biomedcentral.com/articles/10.11…
Do current genomic language models (pre-trained on whole genomes) learn a foundational understanding of biology in the non-coding region of human genomes? A new evaluation led by @AmberZqt suggests not yet! 1/N paper: biorxiv.org/content/10.110…
There is still time until July 18 to submit an abstract to CSH Asia conference “Nuclear Architecture and Function”. Check out the fantastic lineup of speakers! csh-asia.org/?content/2743
The Cold Spring Harbor Asia (CSHA) meeting - Nuclear Architecture and Function is coming up soon! (Sept 1-5, 2025). Abstract submission deadline extended to July 18. Fantastic speakers & beautiful city (Suzhou) with Royal Garden. Check out here: csh-asia.org/?content/2743
Pretty pleased with what I’ve seen inside this model (aka sequence rules learned), some of their predictions better recapitulate our CRISPR experiments in mouse than our own, smaller models. Excited to see the release!
Happy to introduce AlphaGenome, @GoogleDeepMind's new AI model for genomics. AlphaGenome offers a comprehensive view of the human non-coding genome by predicting the impact of DNA variations. It will deepen our understanding of disease biology and open new avenues of research.
Excited to launch our AlphaGenome API goo.gle/3ZPUeFX along with the preprint goo.gle/45AkUyc describing and evaluating our latest DNA sequence model powering the API. Looking forward to seeing how scientists use it! @GoogleDeepMind
This a really exciting leap forward for genomic sequence to activity gene regulation models. It is a genuine improvement over pretty much all SOTA models spanning a wide range of regulatory, transcriptional and post-transcriptional processes. 1/
Happy to introduce AlphaGenome, @GoogleDeepMind's new AI model for genomics. AlphaGenome offers a comprehensive view of the human non-coding genome by predicting the impact of DNA variations. It will deepen our understanding of disease biology and open new avenues of research.
AlphaGenome is now available in preview via our API. Find out more ↓ goo.gle/4lnk6RJ
very cool.. nature.com/articles/s4158… Conservation of regulatory elements with highly diverged sequences across large evolutionary distances
Perspective on recent developments and challenges in regulatory and systems genomics academic.oup.com/bioinformatics… is out, amazing to think about this with @JuliaZeitlinger, @ferhatay, @mahonylab, @AMathelier, @AleMedinaRivera, @jernst98!
There is still time to submit an abstract! The deadline is now extended to May 14.
Like regulatory genomics? Then don’t miss this very fun meeting. The deadline for early registration and abstract submission is May 7: asbmb.org/meetings-event…
Like regulatory genomics? Then don’t miss this very fun meeting. The deadline for early registration and abstract submission is May 7: asbmb.org/meetings-event…
👏 Join us in congratulating Stowers Investigator Jerry Workman, Ph.D., on his election to @theNASciences—one of the highest honors in #science. Elected for his pioneering #research in gene regulation. #NASMember Read more: bit.ly/4cZ6fhJ
Are you interested in the intersection of #AI and molecular #biology? Come to our @KeystoneSymp this September in beautiful Santa Fe! keysym.us/KSAIBio26 #KSAIBio26 Scholarship and short talk deadline May 20 so apply soon! Look forward to seeing you there! #AcademicTwitter
Congratulations to Investigator Jerry Workman! 👏
We are thrilled to announce the election of 120 members and 30 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. Congratulations to our new #NASmembers and welcome to the Academy! 🎊
So happy to see this published now! We present TGIF, Tree-Guided Integrated Factorization, based on multi-task NMF to examine dynamics of the 3D genome organization. genome.cshlp.org/cgi/content/lo… with rockstar student, now Dr. Erika Da-Inn Lee @dyneofdata.
Science-related art, or why we still need journals: Credit: @MelanieWeiler and Martha Weiler. Also a nice paper: cell.com/cell-genomics/…
New #research from the @ZeitlingerLab uses #AI to decipher how cells respond to developmental cues, potentially paving the way for personalized #medicine + original artwork from the lab was selected for the cover of @CellGenomics. Read more: bit.ly/426OoSg
Interpreting regulatory mechanisms of Hippo signaling through a deep learning sequence model dlvr.it/TK55TX
PISA: a versatile interpretation tool for visualizing cis-regulatory rules in genomic data biorxiv.org/content/10.110…
PISA: a versatile interpretation tool for visualizing cis-regulatory rules in genomic data biorxiv.org/content/10.110… 🧬🖥️🧪 github.com/mmtrebuchet/bp…