Jacob González Isa

Jesús Álvarez interviewed me some weeks ago for @abcdesevilla newspaper. Today it's published (physical and online).🥺 share.google/WD9sLdApuDiMUh… Thanks @BecariosFLC for funding my studies abroad. They don't ask where you come from. They don't care about your origins.🥺 💚🤍💚

🥺❤️gracias

TreeProfiler: Large-scale metadata profiling along gene and species trees biorxiv.org/content/10.110…

Thanks again for making this possible! @BecariosFLC @plantsci My first year in Cambridge is being amazing - I am learning so much and involved in so many super exciting projects. It could not have been better!! aljarafenoticias.com/2025/06/06/un-…

A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @plantsci jobs.cam.ac.uk/job/51488/

FastAAI: efficient estimation of genome average amino acid identity and phylum-level relationships using tetramers of universal proteins | Nucleic Acids Research | Oxford Academic academic.oup.com/nar/article/53…

One of the most-viewed PNAS articles in the last week is “The emergence of eukaryotes as an evolutionary algorithmic phase transition.” Explore the article here: ow.ly/NsBj50VHePv For more trending articles, visit ow.ly/FRoU50VHePu.

I read an insanely beautiful ML paper yesterday. It made me happy—and also sad. There is an infinite list of incredible things to learn about. The orchard of science is far too expansive for one person to traverse in any detail. And that principle extends to everything. There…

3D #genome organisation in 🦟 🟡Hi-C patterns associated with epigenetic profiles & gene expression 🔵Chromatin architecture conservation in synteny blocks for 10s of mill. years 🟣Enrichment of synteny breakpoints in regions with high genomic insulation nature.com/articles/s4146…

PTM-Mamba is out in @naturemethods!! 🥳 PTM-Mamba is the first/only pLM to encode both WT and post-translationally modified residues as tokens! And we do this without losing any base protein information from ESM-2! 🤝 📜: nature.com/articles/s4159… 💻: github.com/programmablebi… We…

Pre-registration is now open for our second (free) course on phylogenomic data analysis and visualization using ETE, funded by @cziscience. First time to cover new ETE4 features: Interactive viz of huge tree, profiling... travel fellowships available! eventos.upm.es/130955/detail/…

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Prof. Martin Steinegger's team at SNU has developed Foldseek-Multimer, a rapid and highly sensitive protein complex structural aligner. This breakthrough allows for the comparison of billions of complex pairs in just 11 hours. By computing complex alignments, Foldseek-Multimer…

Higher order repeat structures reflect diverging evolutionary paths in maize centromeres and knobs biorxiv.org/content/10.110… #biorxiv_genomic

so nice

🧬📝🚨 Out today: A genomics learning framework for undergraduates We hope this will be one more tool to help integrate genomics into undergraduate education by supporting evidence-based curriculum design with a set of standardized concepts. journals.plos.org/plosone/articl…

Proud of @Conesa_Lab and @MSCActions @LongtrecEU amazing doctoral candidate @Tian_Yuan_Liu for this timely and comprehensive review on how #LongReadSequencing can profile the epigenome to reveal complex chromatin states. Published today in @NatureGenet. nature.com/articles/s4158…

Mumemto: efficient maximal matching across pangenomes biorxiv.org/content/10.110… 🧬🖥️🧪 github.com/vikshiv/mumemto

Centrophilic retrotransposon integration via CENH3 chromatin in Arabidopsis @Nature from Tetsuji Kakutani & colleagues - beautiful insights into control of transposon insertion into the centromeres nature.com/articles/s4158…