Institute of Human Biology
@IHB_Research
Cutting-edge research into #Organoids, #HumanModelSystems & #Microtechnology from #TeamIHB and other experts in the field. A proud part of the @Roche family.
📢Big News! #TeamIHB welcomes Gaudenz Danuser, Co-Director for Computational Biology! Under his leadership, we will build a new research core with bespoke capabilities to drive breakthrough discoveries in human biology! 👏@gdanuser1 #RocheInnovation #pRED go.roche.com/eekpj
Kidney #organoids represent a powerful and versatile in vitro platform that can accelerate research into fundamental kidney development, disease mechanisms, and drug discovery. More about the image go.roche.com/khb3i #TeamIHB📸🔬:Saba Rezakhani & Irineja Cubela.
🤩Rémi and @EPFL_en, excellent article on #organoids and thank you for highlighting @TheLutolfLab and #TeamIHB's work.
🔬🧫 Organoids, 3D tissues grown from human stem cells have shown great promise over the past 15 years, revolutionizing biomedical research, though they can't fully replace animal testing. go.epfl.ch/61U-en
😍Thanks for the nice science story @Roche on our research just published in @NatureGenet. Congrats to all the scientists involved #TeamIHB #pRED @ETH_BSSE @HelmholtzMunich
#Organoid atlases developed by @IHB_Research @ETH_en & @HelmholtzMunich are now part of the @humancellatlas —laying the groundwork for precision models & future therapies. Built by global collaboration, powered by AI, designed to accelerate human disease modeling. Find out more…
Congrats @_xuquan @HalleLennard et al on your @NatureGenet paper of an endoderm organoid atlas harmonizing diverse data. Exciting applications to assess fidelity, characterize perturbed and diseased states, and streamline protocol development. #OpenAccess🔗go.roche.com/msylq
Integrated Organoid Atlas benchmarks new protocols, even more impressive as a Highly Variable Cohort for comparison against perturbation and disease models: nature.com/articles/s4158… Lead by @_xuquan @HalleLennard Collaboration with @fabian_theis @TreutleinLab @IHB_Research
#TeamIHB is ready for @_industrienacht! Come visit our booth tonight in the @Roche #pRED Center and learn all about how #organoids are changing the way drugs are developed! #RocheInnovation #Basel
.🤩! Great to see these #Organoid Cell Atlases out and the data made available! 👏#TeamIHB is proud to be part of this effort!
The first two integrated HCA Organoid Cell Atlases, from brain and endoderm tissues, are available on the HCA Data Portal. Congratulations to all involved! data.humancellatlas.org/hca-bio-networ…
Congratulations to @freerangemarina @GrayCampLab and all authors @ETH_BSSE @IMBA_Vienna @Roche pRED #TeamIHB @ubclifesciences @viennabiocenter @MedUni_Wien @Helmholtz_HZI @biozentrum @UniBasel_en @ETH_en
It was fun to learn about blood vessel organoids together with @freerangemarina and @TreutleinLab! Thanks to Reiner Wimmer and @penningerlab for introducing us to this system! cell.com/cell/fulltext/…. Great support from editors and reviewers @CellCellPress!
Well done @TheLutolfLab! #TeamIHB #organoids
Kicking off this morning’s #AACR25 plenary, Matthias Lutolf (@TheLutolfLab) of @IHB_Research presents cutting-edge #bioengineering advances in next-generation patient-derived organoid models for solid tumors. #MoffittAAACR25
Congratulations @HansClevers and @_Hubrecht for this Animal Welfare Research Prize! Well deserved recognition for this important work towards #3Rs
#organoids made it into the main German news show: ARD Tagesschau! tagesschau.de/wissen/forschu… @_hubrecht @_IHB_Research @Roche
We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to study regulators of intestinal differentiation or nutrient uptake, please apply! go.roche.com/skt2b and go.roche.com/wf7hj @IHB_Research
Open position for a talented student in my group at @IHB_Research . Working closely with @AntonioSantinha , you will have the opportunity to use organoids, immune cell co-cultures and high-content CRISPR screens to study CRC carcinogenesis. go.roche.com/r7syy
🚨Open position alert! #TeamIHB's #Organoids Gene Editing Group seeks and INTERN to develop screens focused on dissecting mechanisms of intestinal nutrient uptake in human enterocytes. More at go.roche.com/wf7hj #sciencejobs @BeumerJoep
✍️💪Our #NextGenBioeng fellows took their comms skills from theory to application! Through hands-on workshops & personalized feedback, they practiced communicating science with clarity & impact. Thanks @Seyens for the expert guidance! #TeamIHB, @Roche pRED, @ETH_BSSE, @ETH_en
Great paper Wang et al! #TeamIHB is delving into this read for our mid-week deep dive! Shoutout to our very own @NinoukAkkerman- congrats!
Daisong Wang et al report that BEST4/CA7+ gut cells regulate electrolyte and water balance in response to diarrheal bacterial toxins These cells greatly increase in number when exposed to IFNγ cell.com/cell-stem-cell…
.#TeamIHB is excited!!! Can’t wait to connect and talk about all things #organoids!
REGISTRATIONS ARE NOW OPEN! conferences.unibas.ch/frontend/index… Date: June 23-25, 2025 Venue: ZLF Hörsaal, University of Basel Registration: 300 CHF (regular), 100 CHF (with abstract submission) Deadline: April 28th Join us to stay updated on the latest advancements in #organoids!
A big thanks to @SItzkovitz of @WeizmannScience visiting #TeamIHB! We were fascinated to learn how spatial and shed cell transcriptomics of the human digestive tract can illuminate how single cells in mammalian tissues collectively achieve physiological goals.
🚨Open position alert! #TeamIHB seeks a motivated Senior Associate to support our cell line and organoid biorepository and help improve our capabilities for #biobanking. More at go.roche.com/4wp0o #organoids #humanmodelsystems
