Gray Camp

What makes our cells human? The evolution of human development is undeniably fascinating. It is an exciting time to explore the details! We, @brainevodevo, @craiglowe, @KlkUmut, @NatureRevGenet review and suggest new inroads: rdcu.be/c4Pno #sapiens #evodevo #organoids

Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. science.org/doi/10.1126/sc… @HsiuChuan_Lin @JasperJanssens7 @TreutleinLab @ScienceMagazine @ETH_BSSE #NGN2 #ASCL1

My postdoc work at @TreutleinLab @GrayCampLab with @JasperJanssens7 is out in @ScienceMagazine! We screen for neuron subtypes using pro-neural TFs + morphogen combinations + scRNA-seq and profiled over 700,000 cells in 480 conditions. science.org/doi/10.1126/sc…

Very happy to share it’s online! If you read the bioRxiv, updates include tracking cells and tissue flow, Histo4i time course (69 Abs) comparing spatial patterning and a new WLS KO ipsc line establishing mechanosensing via YAP-WNT caudalizes organoids nature.com/articles/s4158…

Check out our latest work where we built a single cell perturbation atlas of niche cues in inflamed human intestinal organoids. We hope this resource will be of value in generating therapeutic hypotheses to guide diseased epithelium back to homeostasis. biorxiv.org/content/10.110…

The Single-cell Analytics Innovation Lab @MSKCancerCenter is looking for ML-oriented computational biologists. Join our team based in NYC to work on cutting-edge single-cell & spatial transcriptomics methods in collaboration with leading research labs. bit.ly/4lTEr2t

Interested in applying for the 2025 Stem Cell Summer School? Don't delay, the deadline is 30th May! Application form and more details about the summer school can be found here: stemcellsummerschool.org/apply

🦇🧫🦠 An organoid platform to study bats' resilience to viral infections - spearheaded by Max Kellner and supported by a great team & collaborators: nature.com/articles/s4159…

Without its international students, Harvard is not Harvard. hrvd.me/IntStudents25t

Drs. Marina Nikolova (@freerangemarina), Barbara Treutlein (@TreutleinLab), and a team at @ETH_en used multiomic #SingleCell analysis to reconstruct blood vessel organoid development! 🩸 @CellCellPress paper: bit.ly/3GstKTZ Discussion: bit.ly/4jWDX9T

It was fun to learn about blood vessel organoids together with @freerangemarina and @TreutleinLab! Thanks to Reiner Wimmer and @penningerlab for introducing us to this system! cell.com/cell/fulltext/…. Great support from editors and reviewers @CellCellPress!

1/ Excited to share CellFlow, a new approach for complex perturbation modeling in single-cell genomics based on flow matching. From cytokine screens to cell fate and organoid engineering, we show CellFlow’s broad power across many diverse tasks. 👉 Paper: biorxiv.org/content/10.110…

We are searching for 2 talented MSc students to join the group! If you are interested in using advanced organoid models to study regulators of intestinal differentiation or nutrient uptake, please apply! go.roche.com/skt2b and go.roche.com/wf7hj @IHB_Research

“I’ve never thought that this would be accomplished in my lifetime” Researchers have successfully sequenced the complete genomes of six ape species go.nature.com/4lpDn5Q

Attention evolution afficionados!! A new European Conference of Comparative Neurobiology (ECCN) is coming up in beautiful Alicante (Spain). Join us with a spectacular list of speakers, highlighting our keynotes Gilles Laurent, Alain Chedotal, Laura Fenlon and Henrik Kaessmann