Stephanie Grach MD MS
@GrachStephanie
@MayoClinicGIM Physician specializing in ME/CFS, Long COVID, & associated complex disease | Assistant Professor of Medicine | She/Her/Hers
Thrilled to announce that our Concise Review, 💥 Diagnosis and Management of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome 💥 was published this week! Honored to have worked with the incomparable @exceedhergrasp1, @Ravi_Ganesh_MD, and Dr. Tony Chon on this paper. (1/)


The first paper that uses our Pacing Narrative Study data is now published. Thank you to all who participated! @GrachStephanie is building a case for vocal differences to detect PEM. She found many discussed such issues during a crash. mdpi.com/2077-0383/14/1… #MECFS #pwME
I am devastated by the loss of Minnesota State Representative Melissa Hortman and her husband, Mark, in a horrifying act of violence. Our prayers are with their children and all who loved them, and with State Senator John Hoffman and his wife, Yvette, who were also targeted.…
In our #rapamycin pilot, we developed 2 biomarkers to measure autophagy function & showed that they correlate to positive response in #MECFS. Our bold goal is to generate a biomarker test to predict likely responders to rapamycin. We’re on our way to a 1st for #ME: test-to-treat!
We are excited to share some early results of our low dose rapamycin project in #ME, in its pre-print version here. TY to @ggottschalkPhD, @AvikRoy74969264 & Dr. David Kaufman for leading it, to all our collaborators & to study patients! #MECFS 1/9 researchsquare.com/article/rs-659…
We found that a significant proportion of the patients who finished the three month trial period of rapamycin (an mTOR inhibitor) showed improvements in both clinical features of the illness (PEM) and saw improvement in blood based markers of autophagy function
Patients with chronic disorders are often dismissed or misdiagnosed. But a new #UBSSW and @Jacobs_Med_UB study offers recommendations to help physicians better communicate with—and treat—these patients: tinyurl.com/UBSSW-NeverWor… ⚕ #UBuffalo #Up4TheChallenge @njsmyth @dysclinic
So psyched to have @GrachStephanie present some early data on @RedefiningMECFS rapamycin study. Without clinicians like Dr Grach, and our other clinical experts me and @AvikRoy74969264 would have no patients to study. Manuscript is forthcoming! #MECFS #longcovid
Had the honor of presenting the initial patient-reported outcomes of the collaborative rapamycin study led by @RedefiningMECFS at @ACPIMPhysicians #IM2025 today! Had an amazing time talking with clinicians from all over the country about advancing the knowledge and care of #MECFS
This work underlies @RedefiningMECFS's #rapamycin trial, which we are so excited to move into the next phase with @agelessrx_ in collaboration with @BatemanHorne @GrachStephanie David Kaufman and others! simmaronresearch.com
Incredibly honored to have received the Mayo Model of Care Award tonight. I am so thankful to my friends and colleagues for their support of me and the patients we serve 💙 @MayoClinicGIM

The latest paper from the Cornell Center is available at the PNAS website. Our study implicates T cell exhaustion in ME/CFS.
2/3) Here is a assessment by Brian Hughes, who states “Something seems very off about how it’s all done”. He discusses the critically flawed methods used by the authors: thesciencebit.net/2024/11/28/tha…
Great news! #MEAction & the Mayo Clinic have been awarded the Sigma 2024 American Nurses Credentialing Center Evidence-Based Practice Implementation Grant awarded by The STTI Honor Society of Nursing. Details: meaction.net/2024/11/18/mea… #pwME #MECFS #MyalgicEncephalomyelitis