Bret Freudenthal
@Freudlab
Associate Professor studying the interplay between DNA damage and human health. WY➡️CSU➡️UI➡️NIEHS➡️KU. Personal tweets from science to society.
New PI Lesson #508 - be very clear when providing the title of your seminar. 🤦♂️ #needmoresleep #sicktoddler

I spoke with an NIH program officer yesterday who said that, given the massive 44% cut planned for NIH, they were only planning to award about 12 new grants before the end of the year, which are mainly ones in the 1st and 2nd percentile, so the 3 grants we had with good scores…
The NIH has decided that scientists can only submit 6 grants a year. OK. But you need a score that’s < 10% at least to get funded. Meaning, at best, 1 out of 10 grants you submit will have a chance (YMMV of course). 🫠
Check out this flyer for an awesome opportunity for students! Registration link here: qokzx.share.hsforms.com/2gmO3e0t6QduV0…
Our new work @biorxivpreprint 🔗biorxiv.org/cgi/content/sh… BRD4-NUT forms liquid-like condensates that locally constrain nucleosomes via bromodomain-mediated crosslinking: physical control of #chromatin by #LLPS transcription condensates. @semeigazin @katsu_s_minami @MasaAShimazoe
The #EMGS is pleased to announce the winner of the 2025 Samuel H. Wilson Award for Studies on DNA Repair, Dr. Mark Hedglin, PhD! Don't miss his presentation, "Rad6 Is Dynamically Accessible for Activation Within the Rad6(Rad18)2 Complex: Mechanistic Insights into a Ubiquitin…
Congrats Mark!
Congratulations to Mark Hedglin, PhD: the 2025 Samuel H. Wilson Award for Studies on DNA Repair Winner @EMGSUS emgs-us.org/news/news.asp?…
🧵 When Congress passed the Inflation Reduction Act in 2022, I thought we were turning a corner and felt hopeful for my kids, our economy, and the planet.
Passage of the climate legislation today is monumental. It will transform our economy’s use of energy and decouple carbon intensity from our energy system. It will make ambitious climate action cheaper for us and the world. It gives our kids a chance to address climate change.
Looking for a deep dive into 2D classification in #cryoEM? These recent guide pages cover practical aspects & parameter choices when running these jobs in #CryoSPARC, along with the theory behind expectation maximization: guide.cryosparc.com/processing-dat… and guide.cryosparc.com/expectation-ma…
Meet Anna Holland, a graduate of Shawnee Mission East who spent the 2024–25 academic year in Dr. Ryan Barnes’ lab at The University of Kansas Cancer Center. With a passion for biomedical research, Anna spent her time learning about the complexities of genomic instability in…
I’ve been urged by colleagues to broadcast this loudly @NIHDirector_Jay @RobertKennedyJr 🎤 🇺🇸 📣 📢 ☎️
I hope severe budget cuts to @NIH and @theNCI can be avoided to minimize disruption to research progress and a more reasonable budget is passed. Our community needs to plan for US leadership in biomedical research so breakthroughs can help people here and everywhere. @HHSGov
Congratulations @kaitlindehart on an outstanding PhD defense! I can’t believe another student has graduated from lab. #proudPI🥹



This messy Trump-Musk breakup is truly the gayest thing about pride month
this is like kendrick vs drake but with two drakes
The secret to how nucleosomes shape the genome | Journal Club | PNAS pnas.org/post/journal-c…
Happy 10th birthday boys! It has been a busy few days celebrating your birthday with laser tag in KC and a trip to the Bahamas. Proud of the incredible boys you are becoming 🎉🎂🎂🥳




Well this is an interesting photo shoot in Kansas City 🫣🤷♂️
