Florian Sicklinger
@FloSicklinger
Physician-Scientist, investigating innate immunity in cardiovascular disease @uniklinik_hd
Thanks to @BronwynBerkeley for highlighting our method in @NatRevCardiol
Read my Tools of the Trade article, published in @NatRevCardiol, highlighting my experience with and the method of ultrasound guided induction of myocardial infarction: rdcu.be/dLgU3 Thanks to @FloSicklinger & F. Leuschner for developing such an innovative method.
Sicklinger & colleagues developed a new #ultrasound-guided method to induce #HeartAttacks in mice, allowing precise control & real-time monitoring without the need for invasive surgery. Learn more at ahajrnls.org/42R7ZGs @volkersmirko @junedh_amrute @rkramann
Check out the latest issue of @CircRes with our Echo-Guided IR Method on the cover ♥️ 🥢
@CircRes May 9th Issue is Out! ahajrnls.org/3wPOBJJ Cover: Representative IF staining of endothelial cells (magenta), inflammation (yellow), & WGA (green) in a 4-chamber view of a heart 7 days after Echocardiography-Guided Induction of I/R;nuclei-blue.
In @Nature we use single cell multiomics, fibroblast fate tracing, and in vivo models to characterize immune fibroblast crosstalk in heart failure with @LavineLab @washumedicine, @Amgen , and @ImmunoFibHF nature.com/articles/s4158…
Check out our paper just published in Circulation ➡️ Translation controls inflammation after myocardial infarction doi.org/10.1161/CIRCUL… This work was a huge collaborative effort over many years. @dzhk_germany @DGK_org @VolkersMirko Key findings + paper summary below 🧵⬇️⬇️⬇️
Very happy that our manuscript is now online @CircAHA. Transient inhibition of translation protects against #reperfusion injury. Kudos to first author @ChrlsHofmann and to all Co-authors for a great team effort. @CRC1550 @dzhk_germany @uniklinik_hd ahajournals.org/doi/abs/10.116…
A shortcut to the infarcted heart Excited to share our collaborative effort with @DenisSchapiro lab led by @FloSicklinger and @FloWuenne. Using spatial omics technologies, we found a new way how monocytes sneak into the infarcted heart. biorxiv.org/content/10.110…
I am very excited to share our lab's first preprint @uniklinik_hd together with the @LeuschnerLab. This study was led by @FloWuenne and @FloSicklinger. biorxiv.org/cgi/content/sh…
🩵💙🩵💙great symposium - great people - great location!! 🩵💙🩵💙#ImmunoCardiology @jacksonlab #leducq #immunofibHF
Florian Leuschner Kicking off the first US immunocardiology conference at @jacksonlab. @ImmunoFibHF Very excited about what’s in store the next three days! #CardioTwitter #cardioimmunology
Exciting news for #Immunology and #Cardiology enthusiasts! Join us at #ImmunoCardiology2023 this September 21-23 in beautiful Bar Harbor, Maine to explore the intersection of these fields and discover the latest breakthroughs in #hearthealth research. Register now! #ImmunofibHF🩵
The #mdcBerlin is very concerned about an ECI request to immediately phase out animal testing. We support the joint @EULIFE_news and @LERUnews statement: mdc-berlin.de/news/news/join… Researchers like our group leader @gabrieleschiat1 explain why we can't avoid animal testing yet 👇
What’s the difference between fibrosis in HFpEF vs HFrEF❓Check out our new preprint!✅ Thanks to my co-first @jan_lanzer from @saezlab for the fruitful collaboration: biorxiv.org/content/10.110…
📰New preprint w Leuschner group @UKHD applying single-cell transcriptomics to heart failure w preserved ejection fraction (#HFpEF) 🏥. We address current gaps in the understanding of fibroblast activation across 🐁 HF models: biorxiv.org/content/10.110…
I am excited to announce, that we have an open #spatialomics staff scientist position for our cross institutional multi-space platform (health-life-sciences.de/multi-space-pl…) as part of @ResearchLifesci karriere.klinikum.uni-heidelberg.de/index.php?ac=j…
Let’s bridge the translational gap by capturing the cardiac immune cell landscape @LavineLab @ImmunoFibHF ahajournals.org/doi/10.1161/CI…
Find out more how the different cells of the heart team up in the healing process and how disturbance of these cruical interactions can lead to heart failure #heartfailure #aging #regeneration science.org/doi/10.1126/sc…