Leuschner Lab

Read my Tools of the Trade article, published in @NatRevCardiol, highlighting my experience with and the method of ultrasound guided induction of myocardial infarction: rdcu.be/dLgU3 Thanks to @FloSicklinger & F. Leuschner for developing such an innovative method.

Check out the latest issue of @CircRes with our Echo-Guided IR Method on the cover ♥️ 🥢

In @Circres we describe a novel Echocardiography-Guided Method for Induction of Myocardial Ischemia/Reperfusion. Check out the full study here: doi.org/10.1161/CIRCRE… Great collaborative effort with @leuschnerlab, @lavinelab, @jacksonlab @rkramann @dzhk_germany @ImmunoFibHF

scRNA-Seq profiling of 🫀interstitial cells reveals fibrosis in HFpEF to be distinct from HFrEF including the induction of basement membrane collagens and a protective ⬆️ of ANGPTL4 in murine and human HFpEF | led by @LauraWienecke and @jan_lanzer doi.org/10.1007/s00395…

What do Angptl4 and collagen IV have to do with fibrosis in HFpEF?🫀 Proud to have found some answers!🔬 Thanks to my co-first @jan_lanzer, all authors and our supervisor team for excellent support @LeuschnerLab @JulioSaezRod 👌🏻 link.springer.com/article/10.100…

Molecular fibroblast activation patterns in heart failure. link.springer.com/article/10.100…

Check out our paper just published in Circulation ➡️ Translation controls inflammation after myocardial infarction doi.org/10.1161/CIRCUL… This work was a huge collaborative effort over many years. @dzhk_germany @DGK_org @VolkersMirko Key findings + paper summary below 🧵⬇️⬇️⬇️

Couldn't attend the #Immuno-#Cardiology Symposium @FondationLeducq @jacksonlab? No problem-> read the report 'Linking immune modulation to cardiac fibrosis' here 👉 rdcu.be/dIUBP #fibrosis #cardioimmunology

I am very excited to share our lab's first preprint @uniklinik_hd together with the @LeuschnerLab. This study was led by @FloWuenne and @FloSicklinger. biorxiv.org/cgi/content/sh…