Ali Lashkaripour
@Droplet_guy
Co-Founder & CTO at Velocity Bio. Microfluidics & drug discovery. Formerly at Stanford & Boston University.
(1/5) Microfluidics & AI -- New publications alert!! It's becoming evident that AI can eliminate trial & error from designing functional microfluidic systems! The last piece of my postdoctoral work @fordycelab is now published in Nature Communications: nature.com/articles/s4146…
The 5050 program is an absolute game-changer for spinning out of academia! 🚀 At our MBC Biolabs location alone, FOUR startups have 5050 roots! It brings together a powerhouse of scientists and engineers, sparking meaningful connections! I can’t recommend it enough! 🔥
NIH grants frozen. Discoveries delayed. PhDs pushed out. Academia getting gutted. Innovation must continue. There’s never been a better time for scientists to build startups.
The DelRosso Lab is starting @UCSF 1/2025 and is seeking applicants for a research postbac! We will be developing cutting edge high-throughput approaches to study the relationship between disordered protein interactions and transcription in human cells🔎 aprecruit.ucsf.edu/JPF05341
Check out our @NatureBiotech paper introducing Cyber-Secure Biological Systems and the Living Roadmap website: programmingbiology.org/csbs Contribute to the Living Roadmap with your published work: programmingbiology.org/submit-paper @BostonUniv @cidar_lab #syntheticbiology #integratedcircuits
Improving engineered biological systems with electronics and microfluidics bit.ly/3I0yLnI
Today in @Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III and dBz-deoxy-Taxol. a…
Heading to Drug Discovery Chemistry next week in San Diego? 🌎🌴 Come check out our posters! We will be presenting exciting updates from @velocitybio as we push forward on our mission to discover allosteric drugs using cutting-edge microfluidics and high-throughput screening.
🌍 Velocity Bio at #DDC2025! 🌍 We're presenting 2 posters next week in San Diego at the Drug Discovery Chemistry conference! Come say hi—we’d love to connect! 🌴
.@fordycelab researchers explore what makes some transcription factors more or less selective for their DNA ligands. This work could guide design of more selective DNA-binding proteins for many bioengineering applications: go.nature.com/4hXnEc5
We’re absolutely thrilled to welcome the newest member of @velocitybio! 🚀 Welcome to the team, Dan! It’s been an incredible privilege working with you, and I can’t wait to see all the amazing science and tech we’ll build together! Let’s make big things happen!
We are absolutely thrilled to announce the newest addition to Velocity Bio! Welcome to the team, Dan Tudorica! We are so excited to have you on board and can't wait to see all the amazing things you'll accomplish!
Excited to share for the first time what I've been building at @atriaVC - investing in the next generation of founders in AI + biology at pre-seed and seed. If you're building, it's never too early to start a conversation. DMs are open.
Biotech venture capital is on the precipice of a generational shift. At least, that’s according to the crowd of younger firm founders edging their way in. trib.al/IMovNPE
🚀 Meet Eliel Akinbami, a @bioe_stanford PhD student in the @fordycelab! Their research has led to HT-MEK (High-Throughput Microfluidic Enzyme Kinetics), a groundbreaking technique that condenses years of enzyme research work into just weeks. ⚡🔬 #Bioengineering @Stanford_ChEMH
Excited to share our new preprint on the Taxol pathway! We developed a strategy to systematically activate and identify gene sets in non-model organisms and used it to find 8 new genes in the Taxol pathway, allowing us to biosynthesize Taxol precursors de novo. Surprisingly, this…
🚨Job Alert🚨 Join @velocitybio & help us unlock new drug discovery paradigms! We're looking for a PhD-trained scientist with expertise in protein biophysics and molecular biology to spearhead new quantitative and high-throughput biophysical assays. jobs.ashbyhq.com/pear/401f6f78-…
Interested in intrinsically disordered proteins or transcription factor activation? Or purifying & measuring affinities for 1000s of protein/protein interactions? Check out @nicole_delrosso & Peter Suzuki's preprint (w/ @BintuLab & @alexholehouse) shorturl.at/jEneh (1/n)
🧬How do transcriptional cofactors recognize which genes to regulate?🧬 Check out our new preprint from @fordycelab @BintuLab that tackles this question and provides the first-ever quantitative map of disordered transcriptional protein interactions (1/9) biorxiv.org/content/10.110…
Protein engineers and biochemists (and everyone, really), check out this awesome work by @kadinaj constructing a 160,000-member fitness landscape in the active site of (my favorite enzyme!) TrpB. There's one neat result (among many) that I wanted to discuss in more detail: (1/9)
Happy to share that our work "A combinatorially complete epistatic fitness landscape in an enzyme active site" by myself, @patrickalmhjell, @EllaWD_PhD, Grace Liu, @NJP_Chem, @jsunn_y, and @francesarnold is now out in @PNASNews! (1/15) pnas.org/doi/10.1073/pn…
Interested in high-throughput enzyme expression & characterization? Check out @BLEE9239's new preprint describing DA-MEK, which employs hydrophilic/omniphobic surfaces to create droplet arrays compatible w/ cell-free protein synthesis! biorxiv.org/content/10.110… (1/n)
PearX $250K-$2M investment ~25 teams per co-hort 3 days retreat at Camp Pear 14 weeks in person at Pear Studio SF, a 30,000 sq/ft office space Dedicated recruiter to build your team Demo day with +1000 investors Apply here! 👇 pear.vc/pearx/
I am super excited to announce a very special addition to Velocity Bio – our very first hire! Welcome to the team, Matthew Keefe! It's been an absolute privilege working with you, and I can’t wait to see all the amazing things we'll build together!
We are absolutely thrilled to announce the newest addition to our team and our very first hire at Velocity Bio! Welcome to the team, Matthew Keefe! We are so excited to have you on board and can't wait to see all the amazing things you'll accomplish!
If you are considering the startup world 5050 is incredibly useful and fun!! Highly recommended 👇🏻👇🏻👇🏻
The world needs 10x more scientist-founders. 5050 helps scientists and engineers become great founders and start indispensable companies. Applications open! Startups are the best way to make a real impact with research, but where do you get started? How do you know if…
📢JOB ADVERT: 24 months Research Associate in Molecular Biology📢 Come and develop novel techniques for the Enrichment Of Circulating Tumour DNA For Improved Cancer Treatment, with me and Nick Leslie, in our beautiful campus in Edinburgh, Scotland! RT Pls bit.ly/4b9RQNh
What were the 50 most successful life sciences startups of the past 15 years? 🧬🚀 For our @pearvc Biotech: Bench to Business series, we conducted an in-depth review of these companies that we dubbed the “biotech behemoths.” 🦍 Link here: pear.vc/biotech-behemo…