Daniel Tabin

Great to see my former student and current post stock, TC, making an impact. It’s worth knowing that this is a side gig for TC. his day job is cultural evolution.

Happy to share that our work from the @nmancuso_ lab is out in @NatureGenet! We developed SuShiE, a multiancestry fine-mapping method for molecular traits. doi.org/10.1038/s41588…

Another amazing finding from the lab of my colleague David Reich: Ancient DNA solves mystery of Hungarian, Finnish language origins — Harvard Gazette news.harvard.edu/gazette/story/…

Observation (2) - Linear mixed model estimates are not independent, hence pseudoreplication is everywhere. We demonstrate this by plotting variance component estimates from two non-overlapping samples. This is due to the shared genealogy.

There are much more structural variants within our genomes than previously conceived, >26,000 per person nature.com/articles/s4158… nature.com/articles/s4158…

It's already a busy 2025, and we're still in January! Batting first from the lab, led by @JiTang1024, we present the as-eGRM based on inferred genealogies (ARGs), which reveals ancestry-specific population structure when intersected with local ancestry calls. 🧵and link below!

Our study titled "Ancient genomes from the Yellow River Bend reveal long-distance population interactions between the Central Plains, Steppe, and southern China" has been released officially online at @CellReports on July 22! A joint work based aDNA lab at Fudan University!

Longitudinal section of intestinal villi. Sea pen (Virgularia sp.) from the Bohol Sea.

📣New from Tang & @CharlestonCWKC! 📄A genealogy-based approach for revealing ancestry-specific structures in admixed populations cell.com/ajhg/abstract/…

Ancient genomes from the Yellow River Bend reveal long-distance population interactions between the Central Plains, Steppe, and southern China sciencedirect.com/science/articl…

Excited to share our new preprint on detecting foldback artifacts in long reads with my advisors Matthew Meyerson and @lh3lh3! Stop by poster C-180 on Wednesday at ISMB/ECCB2025 to learn more and chat!

The South African Coloured are descendants of local Khoe-San and Bantu-speaking populations, European settlers, and enslaved individuals from Africa and Asia. New genotype data for 125 SAC individuals from seven locations link.springer.com/article/10.118…

Are you worried about your DNA revealing too much about you? The @washingtonpost says you should be very worried. I have a different take: stevensalzberg.substack.com/p/i-know-genom…

Results suggest that endogenous human aDNA preservation in the stapes is on average two times higher than in the petrous bone. Despite being the smallest bone in the human skeleton, the stapes may be the most optimal aDNA source yet identified. biorxiv.org/content/10.110…

Thrilled to announce that our book chapter was published by @routledgebooks in #OpenAccess. This chapter is part of an outstanding 740-page book that examines the early events of the Bantu expansion in Central Africa from multidisciplinary perspectives. 🧵taylorfrancis.com/chapters/oa-ed…

Observation (1) - Polygenic trait prediction is upper bounded by the demographic model Europeans/East Asians which experienced a severe bottleneck at the beginning has a larger genetic variance than Africans, i.e. they are *inherently* easier to predict genetically.

New preprint! We unveil the profound connection between the Ancestral Recombination Graph and Linear Mixed Models. Guess what? Random effects are merely a consequence of mutations running on a fixed genealogy. biorxiv.org/content/10.110…

I am starting a computational lab at LIOS, Riga, Latvia, and going to recruit a few people. Please DM if you are interested in a postdoc or PhD position in my Metabolic Research Group. I can highly recommend Riga, it is a beautiful city with very good living conditions.