AlbertW_lab
@AlbertW_Lab
Structural biology and biochemistry lab at IGBMC, Strasbourg, France. We are interested in molecular machines executing gene expression.
We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: science.org/doi/10.1126/sc… The work was supported by @IGBMC, @Inserm, @CNRS, @unistra, @ERC_research, @IMC_Bio, and @instructhub. 1/7
First paper of our lab today @Nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! @embl doi.org/10.1038/s41586…
Our new findings on how the ribosome couples with the RNA polymerase are summarized in a movie highlighting the dynamics of the process🎞️🎥 Thanks to Clemens Bretscher for the great animations! - behance.net/cbretscher @embl paper in @biorxivpreprint biorxiv.org/content/10.110…
Max Planck President Patrick Cramer @mpgpresident has written an open letter to the President of @Harvard, expressing his full support to the University & its stance against demands from the Trump administration to change its policies in order to retain federal funding…
We are pleased to share our work on the evolution of translation initiation now published in Nature Communications. Take a look at leaderless mRNAs and eS26 in the small ribosomal subunit of Saccharolobus solfataricus. rdcu.be/d5pgg
Please spread the word: we are looking for PhD students! Interested in supramolecular complexes in gene expression? Go to imcbio-phdprogram.unistra.fr scroll down to “Integrated Structural Biology (LabEx INRT)” for project descriptions and start application process by January 19th!
Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of @MarkertJon tinyurl.com/setd2
Excited to share a pre-print by Vita Vidmar and @borde_celine in collaboration with @OlivierEspeli and @valeroche about the interplay of #Transcription and DNA topology: biorxiv.org/content/10.110…
Wow! Historic!
Our new findings on how the ribosome couples with the RNA polymerase are summarized in a movie highlighting the dynamics of the process🎞️🎥 Thanks to Clemens Bretscher for the great animations! - behance.net/cbretscher @embl paper in @biorxivpreprint biorxiv.org/content/10.110…
Structures of transcription-translation coupling complexes at each stage of the translation cycle (Collaboration between our laboratory and the laboratories of Yue Gao, Jinzhong Lin, and Chengyaun Wang. Extensively expanded preprint. Posted 07/25/24.) biorxiv.org/content/10.110…