Yathish Achar

@yathishJachar

Scientist/ Group head at BRIC-CDFD, DBT/Wellcome Trust IA intermediate fellow. Interested in DNA topology, Chromatin & Genome architecture.

Hyderabad, India

Joined November 2017

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96Followers

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Yathish Achar@yathishJachar · Jan 22, 2020

Our Nature paper is online now.... Negative supercoil at gene boundaries modulates gene topology disq.us/t/3lie39d

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Department of Biotechnology@DBTIndia · Apr 23

.@DBT_CDFD has signed a Letter of Intent with @nanopore Technologies to advance real-time, portable DNA/RNA sequencing. The collaboration focuses on skill development, developing & deploying equitable, scalable diagnostics for forensics, genome mapping and genetic disease…

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Yathish Achar@yathishJachar · Jul 11

#CDFDSeminars 📢 Upcoming Seminar at CDFD Join us for a talk by Dr. Prasanna Venkatraman (ACTREC) on: “Bridging Scales: Connecting In Vitro Structures to In Cellulo and In Vivo Functions” 🗓 July 23, 2025 | 🕛 12:00 PM 📍 CDFD Seminar Hall

yathishJachar's tweet image. #CDFDSeminars
📢 Upcoming Seminar at CDFD
Join us for a talk by Dr. Prasanna Venkatraman (ACTREC) on:
“Bridging Scales: Connecting In Vitro Structures to In Cellulo and In Vivo Functions”
🗓 July 23, 2025 | 🕛 12:00 PM
📍 CDFD Seminar Hall

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Yathish Achar@yathishJachar · Jun 25

#CDFDSeminars Join us for an exciting talk by Prof. Sudha Rajamani (IISER Pune) on "The Emergence and Evolution of Biomolecules on the Early Earth: Implication for Life's Origin" 📅 July 3 | 🕛 12:00 PM 📍 CDFD Seminar Hall

yathishJachar's tweet image. #CDFDSeminars
Join us for an exciting talk by Prof. Sudha Rajamani (IISER Pune) on
"The Emergence and Evolution of Biomolecules on the Early Earth: Implication for Life's Origin"
📅 July 3 | 🕛 12:00 PM
📍 CDFD Seminar Hall

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Yathish Achar Retweeted

Ullas Kolthur@UllasKolthur · Jun 23

Inauguration of ARUMDA National Analytical Facility for Nutrition & Metabolism Research by Dr. A.K. Mohanty (DAE-Secretary). Dignitaries: Dr. Anil Kakodkar (former DAE-Secretary), Prof. Chengalur (Director-TIFR), Prof. M. Krishnamurthy (Center-Director-TIFRH).

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Yathish Achar@yathishJachar · Jun 21

2nd Annual Placement Conclave jointly organised by @DBT_CDFD @HydNiab One of it’s kind event to enable senior PhD students to #network with leaders in #academia and #industry Prospective job offers for students from across iBRIC+ institutions #recruitment

BBRIC-CDFD@DBT_CDFD · Jun 20

NIAB and CDFD, under the esteemed aegis of BRIC, DBT, Govt of India, successfully hosted the iBRIC+ Student Networking and Placement Conclave – 2025 today. #studentplacement #scholars @DBTIndia @UllasKolthur @niab

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Andrés Aguilera@AguileRloop · Apr 25

Glad to share our new work on inhibitors of Topo1 first catalytic step, shown in vitro, in yeast and human cells. Thanks all authors for a great work. @unisevilla @PhrmMar @AgEInves Patulin and Xestoquinol are inhibitors of DNA topoisomerase 1 | PNAS pnas.org/doi/10.1073/pn…

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Shweta Tyagi@ShwetaTyagiCDFD · Apr 24

Stop obsessing over PCM1 !! There is a new kid on the block 🕺👇🏻 Read our review about "CEP72", the centriolar satellite 🛰️ protein to watch for doi.org/10.1002/cm.220… #centrosome, #Mitosis, #CellBiology @AshwinDalal9, @DBT_CDFD ,@CytoskelJournal

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Yathish Achar@yathishJachar · Apr 24

#CDFDSeminars Excited to host Prof. Sanjeev Shukla at BRIC-CDFD! Join us as he explores cutting-edge research on gene regulation and chromatin dynamics. 🗓️ May 1, 2025 | 🕛 12:00 PM 📍 CDFD Seminar Hall

yathishJachar's tweet image. #CDFDSeminars
Excited to host Prof. Sanjeev Shukla at BRIC-CDFD! Join us as he explores cutting-edge research on gene regulation and chromatin dynamics.
🗓️ May 1, 2025 | 🕛 12:00 PM
📍 CDFD Seminar Hall

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Yathish Achar@yathishJachar · Apr 11

Delighted to share this. A novel H4 variant that modulates chromatin to mediate salt stress response. This mammoth work was driven to perfection by @VivekHariSunda1, a wonderful PhD student who also taught me. We report its CryoEM structure & unusual chemistry @NCBS_Bangalore 1/3

NNature Plants@NaturePlants · Apr 9

New Article: "An Oryza-specific histone H4 variant predisposes H4 lysine 5 acetylation to modulate salt stress responses" rdcu.be/eg0Zs An Oryza-specific histone H4 variant (H4.V) forms condensed, less stable nucleosomes, regulating the salt stress transcriptome.

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MS Lab@LcdcsCDFD · Mar 31

How to navigate research challenges and AI's impact in today's science? At ProUPS-25 at @SRM_Univ youtu.be/YZk6JmKJHD0?si…

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Shweta Tyagi@ShwetaTyagiCDFD · Mar 10

CDFD Annual talks under way! Looking forward to two days of exciting science and stimulating discussions… @DBT_CDFD @yathishJachar

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Yathish Achar@yathishJachar · Mar 10

From genome architecture to metabolism ….

SShweta Tyagi@ShwetaTyagiCDFD · Mar 10

CDFD Annual talks under way! Looking forward to two days of exciting science and stimulating discussions… @DBT_CDFD @yathishJachar

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MS Lab@LcdcsCDFD · Mar 6

Witness the depth and the breadth of science we do at @DBT_CDFD Represented @DBT_CDFD in the PDF Satellite Meeting at the #YIM2025 by @IndiaBioscience

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Andrés Aguilera@AguileRloop · Mar 6

If you want to know what have we learned in the field of R-loop homeostasis in 2023-24 and the questions coming ahead @Aguilera_P_90 @unisevilla @cabimer R-loop homeostasis in genome dynamics, gene expression and development sciencedirect.com/science/articl…

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Yathish Achar@yathishJachar · Mar 7

Looking forward to the upcoming 'CDFD Annual Talks-2025'! 🎉 A wonderful opportunity to hear from esteemed invited speakers on cutting-edge research and innovation. #CDFDTalks2025

yathishJachar's tweet image. Looking forward to the upcoming 'CDFD Annual Talks-2025'! 🎉 A wonderful opportunity to hear from esteemed invited speakers on cutting-edge research and innovation. #CDFDTalks2025

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Sagar Sengupta@DrSagarSengupta · Mar 7

Happy to present our work in @embojournal where we show how p53 acts as a transcriptional repressor by directly recruiting DREAM complex in p21-independent manner. Congrats to @AgrawalRitu pubmed.ncbi.nlm.nih.gov/40038454/. @DBTIndia @FollowDbtNibmg @NImmunology

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Sagar Sengupta@DrSagarSengupta · Feb 28

Our recent work in NAR shows a 20-mer peptide can augment DNA damage response by acting as ATM agonist, potentially preventing neoplastic transformation. Great work done by @AgrawalRitu, collaboration with Avinash Bajaj @FollowDbtNibmg @DBTIndia @NImmunology 10.1093/nar/gkaf106

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Yathish Achar@yathishJachar · Feb 12

Excited to share our latest preprint! We explored how septin-associated kinases regulate septin organization and cytokinesis in yeast. Our work reveals new insights into the interplay between these kinases and the actomyosin ring. #septins #cytoskeleton #celldivision #yeast

bbioRxiv Cell Biology@biorxiv_cellbio · Feb 8

Nim1-related kinases regulate septin organization and cytokinesis by modulating Hof1 at the cell division site biorxiv.org/content/10.110… #biorxiv_cellbio

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Ullas Kolthur@UllasKolthur · Feb 4

Mitochondria Time Your Exercise Capacity Did you know your workout efficiency changes with the clock? 🏃‍♀️ Our research uncovers how mitochondrial energetics & SIRT4 regulate exercise performance during the day! 🌞🌙 Find out more: dx.doi.org/10.1096/fj.202… @TIFRScience @TIFRH_buzz

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Shweta Tyagi@ShwetaTyagiCDFD · Feb 3

Had fun talking to CDFD staff and their families about our science as part of Foundation day celebrations. #Fraternitytalks @DBT_CDFD

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