Caly Yu Xiao (肖燏)
@xiaoyucaly
Postdoctoral researcher in DeMON lab, Lund University | Machine learning | Alzheimer’s Disease pregression | multimodality neuroimaging
🧠New preprint alert! Tau, the pathological protein in AD, spreads through the brain in a very particular pattern. But what drives this pattern? We found that WHERE tau pathology appears, and HOW MUCH accumulates there, are governed by different mechanisms. Check out our…
Wondering how to generate good 7T T1-weighted image from a 3T scan? Check out our lasted preprint! 👇
‼️NEW PREPRINT‼️ What if you could take a normal 3T T1-weighted scan and make it look like it was acquired from a 7T scanner? We use AI on 172 paired 3T and 7T scans to improve sharpness and contrast of 3T images Link: arxiv.org/abs/2507.13782 Check out the thread! 👇👇 1/
Rethinking excitation/inhibition balance in the human brain — a Comment article by Roi Cohen Kadosh nature.com/articles/s4158…
How can we predict the multiple neurodegenerative diseases using just blood sample and single model? Check out this awesome work by @anlijuncn
Can AI reveal the risk and co-pathology of multiple neurodegenerative diseases from just a single blood sample? We explored the AI-based diagnostic power on a massive sample (N=17,170) and high-rank plasma proteomics data. medrxiv.org/content/10.110… #MedSky #neuroskyence #neurosky…
Nature research paper: How short peptides disassemble tau fibrils in Alzheimer’s disease go.nature.com/45X7a0J
Single-cell spatial transcriptomic atlas of the whole mouse brain🔥 cell.com/neuron/fulltex…
⚠️ Are you interested in designing impactful studies in AD? In understanding clinical trial design and biomarker frameworks? Will you be attending #AAIC2025 #AAIC25 in our sunny☀️ Toronto? 🔜 then this workshop is for you! 🤩 Register now—spots are limited! ⤵️ @ISTAART
Did you know a pretrained graph transformer can tackle virtually any predictive ML problem? That means accurate predictions for churn, fraud, and recommendations without the endless cycle of feature engineering, model development, and training. This isn't just a concept. Our…
How does brain change functionally with AD and aging? Check out this preprint from @jorittmo of our lab 👇
How does the brain reorganize in the context of age and AD? Are functional changes in age and AD similar? Are these changes dynamic across the age/AD spectrum? We unpack these questions in a sample of N=973 with AD biomarkers Preprint: tinyurl.com/ymv8s7h8 1/ ⬇️🧵
‼️New preprint! We are happy to share our latest work led by @teanijarv investigating why tau pathology in Alzheimer’s disease (AD) often accumulates more in one hemisphere of the brain than the other. Check out🔗biorxiv.org/content/10.110… or dive into the details below👇
🧠Exciting new findings from a great collaboration between the BioFINDER study and the talented @xiaoyucaly from @_JakeVogel_ group!! In their preprint, they show that tau presence and tau load are guided by unique brain mechanisms. Dive into the details here 👇
🧠New preprint alert! Tau, the pathological protein in AD, spreads through the brain in a very particular pattern. But what drives this pattern? We found that WHERE tau pathology appears, and HOW MUCH accumulates there, are governed by different mechanisms. Check out our…