Winklhofer Lab
@winklhofer_lab
Dedicated to elucidate mechanisms of #neurodegeneration: #proteostasis, #ubiquitin, #mitochondria
Please register to get an update on cellular imaging by light and electron microscopy. And of course, to meet friends and make new friends 🤩 #microscopy #cellbiology
The GBM Compact conference „Focus on Imaging“ takes place from September 26-27 in Frankfurt! Early registration+abstract submisison is possible until June 30. Please visit the conference website for registration and further information: gbm-compact.org
And here goes our brand new flyer #postdocjobs. Please RT!
Structural biologists- join us to work on the mechanisms of protein transport to mitochondria! We work in the interdysciplinary group and in collaboration with structural groups. !Structural friends please distribute! 😊
The AMBER call is still open and will close on September 8th. We are seeking a passionate Postdoctoral Researcher to investigate the mechanisms driving protein transport into mitochondria in Prof. Agnieszka Chacińska's group. lnkd.in/etNHhNXf
A successful visit has come to an end.Filip Kuś from the University of Gdańsk received an EMBO Scientific Exchange Grant to study the function of molecular chaperones. Over the last three months, he has obtained impressive data using FLIM. Best of luck with the next steps, Filip!
Please don't forget to submit an abstract! 💌 The deadline (June 30) is approaching: gbm-compact.org/gbm-compact-20…
🚨 New review out in Nature Reviews Molecular Cell Biology! Expert recommendations for studying organelle contact sites and introduce the concept of organelle contactome 🧬nature.com/articles/s4158… Huge thanks to editor Lisa Heinke for the support and guidance! 🙏@NatRevMCB
Join us in Lorne for the 11th ISA. We have a fantastic line up of speakers at a beautiful coastal location in Australia. Hope to see you there!
Michael Lazarou and I will be chairing the 11th International Symposium on Autophagy (ISA) in Australia from 16-20 Nov 2025! 📍 Location: Lorne, Victoria, Australia 🌐 Register now: isa11.org Join us for five inspiring days of cutting-edge autophagy research!
It has has been a successful week: Avinash has been awarded the first poster prize at the IMPRS-LM Symposium and Koustav just received the Cecile M. Pickart Travel Award at the Cold Spring Harbor Ubiquitin Conference. Huge congrats 🥳 #cshlubiq #imprs_lm #ubiquitin
🚀 New paper! 🧬✨Thrilled to share our latest work @cddpress, pushing the boundaries of imaging inter-organelle contacts in vivo! Incredible effort by our talented postdoc Lucia Barazzuol, in collaboration with @alessio_vagnoni and the Marisa Brini Lab. rdcu.be/efkYK🚀
Our paper on bacterial clippases is now out in @MolecularCell. These really interesting enzymes can make deconjugation of #ubiquitin irreversible. Thanks to @UniCologne and @C2fBiochemistry for support. cell.com/molecular-cell…
Join us for the GBM Lunch! 📅 March 12, 2025 🕛 12:30 PM Johannes Broichhagen (Leibniz-Forschungsinstitut für Molekulare Pharmakologie), will be our speaker and present on “Organic Chemistry to shine light on biology” Session chair: Andrea Hupfeld, Regensburg
1 week left - January 31 is deadline for 👇 •Abstract Submission and •Early Bird Registration for the 76th Mosbacher Kolloquium with a fantastic lecture program and interesting lunch break events: mosbacher-kolloquium.org/home.html
Wonderful news! Congrats, Anne 🥳
Congratulations to Anne Spang @Spang_Lab for receiving the renowned Lelio Orci Award. The award honors her pioneering work in intracellular organization and her research achievements in Cell Biology. @LS2Switzerland @UniBasel_en biozentrum.unibas.ch/news/detail/an…
New to #ubiquitin? Been with it for a while? Either way this review may be for you 🤩: Excited to share our review article in @MolecularCell , diving deep into everything #ubiquitin Read here 👉 kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F%2… @CellPressNews @WEHI_research @komander_lab
👉bei Anmeldung bis März 2025 ist das erste Jahr der Mitgliedschaft kostenfrei! If you register by March 2025, the first year of membership is free of charge! I
Freshly published from us! We demonstrate an amaizing regulation of the TIM23 machinery for protein import into mitochondria. One form of this machinery, TIMM17A is constantly degrated, and only sometimes saved from destruction by OCIAD1. pubmed.ncbi.nlm.nih.gov/39630581/
Postdocs in biochemistry & molecular neuroscience in Berlin to study presynapse formation in human neurons funded by the ERC (see leibniz-fmp.de/haucke; Rizalar et al Haucke (2023) Science). A few more days left to apply: [email protected].
Very excited to share that our manuscript on the "Discovery and mechanism of K63-linkage-directed deubiquitinase activity in USP53" was published today at Nature Chemical Biology @nchembio. Congratulations Kim, Kai, and all authors! nature.com/articles/s4158…
For all ubiquitin, deubiquitinase and chemical biology aficionados: Here's a preprint from the lab introducing 2 new active DUBs in humans & a unique type of DUB activity one would miss with the widely used panels of free ubiquitin chains. t.ly/GnRVv Thread👇(1/10)
#GBMLunch on Wednesday Oct 30, 12:30 pm: Claudio Acuna from University Heidelberg, Title: "Human presynaptic function in health and disease", organized by Antje Ebert from @uniGoettingen & GBM Study Group #Receptors and #Signaltransduction, more on gbm-online.de/de/gbm-lunch.h…