Jae Kyoung Kim
@umichkim
Prof. Math, KAIST & Chief Investigator, BIMAG, IBS. Love to solve problems of biology and medicine with math.
Today I am going to give a talk about our sleep research at the Chinese University of Hong Kong Medical School (3:30-4:30pm KST)! You can join via zoom!

Predicting microbial community dynamics is hard: mechanistic models lack flexibility, ML models overfit & ignore physics. This study proposes NSM—a physics-constrained neural ODE. Accurate, interpretable, data-efficient. biorxiv.org/content/10.110…
[월간중앙]박진영 뉴욕대 교수 20년간 이산수학계의 난제 ‘칸-칼라이(Kahn-Kalai) 추측’ 증명 마리암 미르자카니 뉴 프런티어 상 수상 등…세계 수학계 스타 등극 “저처럼 모든 늦깎이 인생에게 힘이 되길…” m-joongang.com/news/articleVi…
Can the heart itself trigger fatal arrhythmias during #seizures? Our latest study combines math modeling & circadian biology to reveal intrinsic cardiac drivers of seizure-induced arrhythmias—challenging neurogenic dogma. #Sleep-wake timing matters. doi.org/10.1371/journa…

[With Science, We Live] Mathematics: The Language of Life youtube.com/watch?v=5WnOgt…
Olive Cawiding Joins Global Scholars at the UN Research Institute for Social Development’s leadership training in Geneva. Olive Cawiding 학생이 유엔 사회개발연구소(UNRISD) 주관 리더십 연수에 글로벌 장학생으로 참여했습니다. ibs.re.kr/bimag/2025/07/…
Aqsa, a graduate student researcher, received the Outstanding Research Award at the Annual Conference of the Korean Sleep Research Society. Aqsa 대학원생 연구원이 대한수면연구학회에서 우수 학술상을 수상했습니다. ibs.re.kr/bimag/2025/07/…
scICE enhances clustering reliability and efficiency for scRNA-seq data analysis @gimhyeo2951042 @umichkim @ibsbimag @IBS_media #Bioinformatics #BiotechNatureComms doi.org/10.1038/s41467…
Our personalized sleep guidance algorithm will be officially integrated into all Galaxy Watches. Thanks to Samsung, our math-based algorithm can help people sleep better and live healthier. From equations to everyday life—this is why we do research. #Sleep #GalaxyWatch #Math


Honored to speak on behalf of the scientific community. Grateful to President Lee for listening directly to researchers, just one month into office. A short talk—but a big step toward building a healthier research ecosystem. youtube.com/watch?v=VFvjo0…
Problem: Popular clustering methods (e.g., Leiden) give different results depending on random seeds. Our solution: scICE – a scalable and 30x faster algorithm to find consistent clustering outcomes, even in large datasets (10,000+ cells)! nature.com/articles/s4146…
아리랑 TV에서 처음으로 과학 프로그램이 시작됩니다! <With Science, We Live> 매주 화요일 오후 3시 본방송 / 오후 7시, 밤 11시 30분 재방송 제가 출연한 ‘수학’ 편은 1편: 7월 15일, 2편: 7월 22일에 방송될 예정입니다. 많은 관심 부탁드립니다!
How do clock proteins behave in the brain’s circadian center? Using live imaging in knock-in mice, Smyllie eshow that PER2 and CRY1 act independently, not as one unit. Their stability, localization, and timing reshape our understanding of the SCN clock. doi.org/10.1038/s44318…
How do cells reliably flip gene switches in noisy environments? We show that combining three indirect repression mechanisms—sequestration, blocking, and displacement—enables ultrasensitive & noise-resistant transcription. biorxiv.org/content/10.110…

“One Experiment Is All It Takes”: KAIST Team Revolutionizes Drug Interaction Testing, Replacing 60,000 Studies news.kaist.ac.kr/newsen/html/ne…
Remember this plot from textbooks? Used in 60,000+ papers to estimate inhibition constants via multiple-dose experiments. We find most of those data are unnecessary—and even harmful. With just ~10% of data + a Cheng-Prusoff prior, we get better ones. nature.com/articles/s4146…
