Tony Yu-Chen Tsai
@tonytsai00
Systems developmental biologist studying how embryos form pattern and change shape robustly in zebrafish Tsai lab @WashUDevBio
Also thanks @WUSTL for the news release. I am thankful for WUSM's nomination so my research has the opportunity to be recognized by @pewtrusts. Looking forward to seeing how these funding can help us discover new mechanisms of developmental robustness. medicine.wustl.edu/news/tsai-name…

🚨🫧💧Online now in @CellCellPress, we define a mechanism that generates patterned curvature at tissue interfaces to begin building mammalian intestinal villi. @ZevGartner @OphirKlein Full text available here: cell.com/cell/fulltext/… Previous🧵👇with some splashy videos💧🫧
💧🫧What do the developing gut and water on your windshield have in common? Check out our new preprint from @ZevGartner and @OphirKlein labs to find out!🫧💧 biorxiv.org/content/10.110… More info in the🧵👇
Excited to share our new study quantifying the information content of morphogen signaling in the zebrafish spinal cord with the @WashUGenetics community. If you are interested in gene expression noise, tissue patterning, and morphogen signaling, join me this Thursday at noon!
Can't wait for @tonytsai00 Genetics Seminar this Thursday about "“How to make precise tissue patterns with noisy instructions?” @WashUGenetics @WashUDevBio
Stunning movie of zebrafish spinal cord morphogenesis from our very own @ChiaTengChang featured on @ZebrafishRock What a beautiful (and mysterious) process!
Time-lapse video of zebrafish spinal cord morphogenesis. Credit to @ChiaTengChang. #ZebrafishZunday
I always consider myself an "in vivo cell biologist". And the zebrafish is a beautiful live imaging model to uncover cool cell biological mechanisms in tissue development. Excited about the opportunity to speak to the Cell Biology community here at WashU! Join me today at 1 pm!
Time-lapse video of zebrafish spinal cord morphogenesis. Credit to @ChiaTengChang. #ZebrafishZunday
Can’t be more proud with Maddie’s @madeline__ryan fantastic talk at #2023SDB on our work of cadherin function in spinal cord morphogenesis. She is applying for grad school this fall! Please watch out for this rising star!

Tsai lab at #SDB2023! Come check out Wyndham's poster on adhesion-based fin patterning (today B166), @ChiaTengChang's poster on positional information of spinal cord (tomorrow B125), and @madeline__ryan 's talk on Sunday 8:50 am on amazing spinal cord morphogenesis phenotypes!

Now out! I'm beyond thrilled to share our method for dynamically measuring neurulation forces. We hope that our addition to the toolkit will push forward the quantification of living tissue mechanics. @ElvassoreL @GabeGalea @UniPadova @DBC_ICH @MSCActions nature.com/articles/s4156…
We’re very excited to share the first preprint from my lab along with @h4rrymcnamara, @BillZJia, @AdamEzraCohen, and Alex Schier. We describe a set of methods for exerting spatial control over Nodal signaling in zebrafish development. biorxiv.org/content/10.110…
Proud PI moment: your technician is accepted to the graduate school that rejected your application 17 yrs ago. Congrats @madeline__ryan for the offer from @BBS_Harvard, making it 7 for 7! We're so excited that you have so many great options for your PhD study! Well-deserved!
Do you know undergrads interested in working full-time in top-notch Dev Bio or Cell Bio labs for 2 years before applying to PhD? The WashU post-bac program offers immersive research experience and training for academic skills! Now open for application! sites.wustl.edu/devbioregenmed…
Per request of @ZebrafishRock, more mustache photos from our first ever lab retreat. This is such a fun group exercise. I hope everyone is excited about testing all the new ideas back in lab (I know I am!)




D2 of lab retreat: chalk talk (with real mustache), describe your dream experiment session, kayaking, hotpot dinner, zebrafish themed jeopardy game hosted by @ZebrafishRock wizard @madeline__ryan, fire pit chat on lab culture. What an action packed fun day! I love my lab!




Waking up surrounded by beautiful fall foliage in central Missouri as we conclude day 1 of our first lab retreat. Chalk talk with mustache, dinner career chat, poker games, lively Disney themed karaoke. I’m so lucky to work with these smart and fun people! Excited about day 2!!




A pattern formation mutant!
A zoo in Tennessee says it has welcomed a rare spotless giraffe. Brights Zoo is holding a contest to name the baby 🦒
One of the great joy as a PI is seeing the excitement of your students as they present their works. Thanks to @SocDevBio #2023SDB for providing such a platform, and all who came, listened, and provided feedback to our works. We had a blast and loved the community!




Every trip to @ISTAustria ends with lots of excitement. Thanks to @HeisenbergCPLab for hosting. Met old friends, gave a talk to engaging crowd, many 1-on-1 meetings with ideas for collaboration, tried new experiments, got cool prelim data. What else can I ask for?

The last but definitely not least @2023EZM our PhD student @ChiaTengChang discusses his work on how BMP gradient regulates gastrulation movements of germ layers in zebrafish. Thanks @eu_fish @InfoIzfs @Danio_polska and Kraków for the fantastic science and interactions 🐟😻
Reassembling the dual pipette aspiration team in Krakow! Meeting with CP @HeisenbergCPLab at #EZM2023 and visiting Matt’s new lab at the Max Planck Dioscuri Center at the Jagiellonian University. Amazing that we are all PI now.
