Stephen Martis

Excited that this is out in @PNASNews ! pnas.org/doi/10.1073/pn… In a sentence, we show that different mutational processes can have different long-term impacts on eco-evolutionary systems. 1/n

Fun project working with @myphysicsvoyage and David! In a nutshell -- in eco-evo contexts, different types of mutational processes can drive different qualitative behavior, including pattern formation a la Turing. Check out the preprint if this sounds interesting to you!

#Preprint alert! Pioneering work by @tanmana_mitra sheds new insights into why T cells become metabolically exhausted during persistent antigen encounter: biorxiv.org/content/10.110…

#Preprint alert! @KevinYTChen, a brilliant @GSKGradSchool graduate student and NCI F99/K00 awardee, identifies a novel, post-transcriptional checkpoint on intratumoral T cell function: biorxiv.org/content/10.110…

Excited to join @WashUPhysics as an assistant professor in Fall 2025! My group will develop non-equilibrium statistical physics to study criticality in biology—biomolecular condensates, gene regulation & adaptive immune systems. DM for postdoc/grad openings! #myphysicsjourney

🚨 Just out @NatureMedicine! Introducing InflaMix—a point-of-care tool that identifies an #inflammatory 🔥 signature predictive of #CART failure in #lymphoma Led by Sandeep Raj (@SSRaj017) 👏@MSKCancerCenter nature.com/articles/s4159… 🧵Let’s break it down

Our latest work on the #darkgenome is out now in @NatureComms. LINE-1 is the only known autonomous retrotransposon in our genome - an ancient genome parasite that can start replicating again in cancer. Co-led by our Alexander Solovyov @MSKCancerCenter @CompOncMSK - our work was…

I am thrilled to see our latest findings out in @Nature -we identify that IL33 induces Tertiary Lymphoid structure via ILC2s. -we show that this pathway is druggable and engineered human rIL33 as potentially a novel immunotherapy! I am glad to have led this study with…

1. Tertiary Lymphoid Structures (TLSs) – on demand lymphoid aggregates that assemble in inflamed tissues/cancer to regulate immunity   But how? What molecule triggers? What cells induce?   TODAY in @Nature nature.com/articles/s4158…   Long-term #PDAC survivor PART4 – TLSs   🧵1/25

New preprint led by postdoc Brandon Schlomann discovering spatial patterns of immune response in fly larvae! biorxiv.org/content/10.110…

We posted a couple of preprints recently, quick summary below 👇

The interplay between proliferating pathogens and the huge diversity of immune receptors, makes the problem of antigen recognition very interesting. The stat mech density of states + noneq binding give a nice framework to study it. Check it out @PhysRevX journals.aps.org/prx/abstract/1…

How do healthy tissues evolve to become cancerous? Delighted to share our latest research tracking the somatic evolution that occurs in the decades before AML. 👇Implications for early detection and early interception. biorxiv.org/cgi/content/sh…

Hello Xverse, we're on the hunt for a postdoctoral fellow to study cellular and systemic metabolism with a quantitative, multimodal toolkit. Is this you or someone you know and love? Reach out!

My student accepted a fully funded PhD in the US, but has had difficulty securing an appointment with the US consulate in Italy. They are now drafting materials for an expedited interview request. If you have advice/materials on how to secure an expedited interview please dm me