StarkLab

Developmental and housekeeping transcriptional programs display distinct modes of enhancer-enhancer cooperativity in Drosophila biorxiv.org/cgi/content/sh… #bioRxiv

Excited to share the final version of my Postdoc work in the @stark_lab on mapping and unravelling the regulatory specificities between transcriptional corepressors (CoRs) and active enhancers. (1/5) science.org/doi/10.1126/sc…

Transcription pre-initiation complex formation & composition is not as uniform as we thought: @stark_lab @IMPvienna finds distinct PICs acting at housekeeping vs. developmentally-regulated promoters in Drosophila cells #RefereedPreprint via @ReviewCommons embopress.org/doi/10.15252/e…

Congratulations to @FilipNemcko PhD (@stark_lab, IMP), who recently defended his thesis: 'Systematic identification and functional characterization of transcriptional regulators' - Well done Filip! 🥂🍾 @univienna @IMPvienna @IMBA_Vienna @gmivienna @MaxPerutzLabs

Nature biotechnology highlighting ours @stark_lab and @steinaerts @ibrahimihsan recent work on designing cell type-specific enhancers 🎉

Research Highlight: Designer enhancers for cell-type-specific gene regulation nature.com/articles/s4158…

🚨 Research paper alert! Functionally distinct #promoter classes initiate transcription via different mechanisms, according to @LeoSerebreni from the @stark_lab & co-authors. Read more in our interview with him. 👇🏽 1/3 imp.ac.at/news/article/c…

Research paper alert! The @stark_lab shows in @genomeresearch that the activity of #enhancers is encoded through a combination of their motifs’ identity & context. 👇🏽 (1/2) News article: imp.ac.at/news/article/d… Paper: genome.cshlp.org/content/early/…

Monika Heinzl from @jkulinz joined the lab of Alex Stark @stark_lab at @IMPvienna to understand and predict the DNA-sequence encoding of enhancer activity.

The @stark_lab investigates how transcription is regulated at the enhancer and core-promoter DNA level & the proteins involved in activation. Their aim is to comprehend transcription, how it defines cellular and developmental programs via transcriptional networks. @IMPvienna