Smitha Krishnamurthi
@smitha42
Gastrointestinal medical oncologist @clevelandclinic. Tweets are my own.
Really impressed by the Resources from the @ClevelandClinic Center for Young-Onset Colorectal Cancer - for patients and their family members @DavidLiskaMD @smitha42 my.clevelandclinic.org/departments/di… @CancerInsider @FightCRC Colon Camp!
💯 % agree “discontinuing trials for which participants have already volunteered and are undergoing treatment does an enormous disservice to patients.”
Read more from our co-chairs on the importance of protecting public support for biomedical research: bit.ly/3IvxNQD #CancerResearch #ClinicalTrials
#ColorectalCancer survivors, we want to hear from YOU! What's 1️⃣ thing that helped you through your diagnosis? Repost and fill in the blank!
This is so sad. Losing our technological and biomedical leadership is truly out of line with making America great. I hope it will be possible to reverse course.
The U.S.’s dramatic research and funding cuts as well as changes to skilled-worker immigration policies threaten one of its greatest economic advantages: people-powered innovation on.wsj.com/44I1bKV
Our latest paper led by @ThejusJay @sangwan_naseer in collab with @ClevelandClinic investigators and @RoswellPark colleagues Iyer, Vadehra, Fountzilas finds distinct microbiotic profiles of early onset pancreatic cancer and an association with survival sciencedirect.com/science/articl…
Inspired by her daughter, Roxana Dronca, M.D., helped create a program that brings life-saving cancer treatment directly to patients’ homes. mayocl.in/46vfxRb
Happy 249th Birthday to the country that (among many, many other accomplishments) created the overwhelming majority of all cancer drugs in existence 💪🇺🇸🇺🇸🇺🇸
🚨 BREAKING: Congress just passed H.R. 1, also known as the One Big Beautiful Bill Act,—and it has serious implications for millions of Americans, including colorectal cancer survivors.
America’s docs, time to get off the sidelines and tell your members of congress what it will mean to your patients if 14 million people in this country lose their health insurance.
An update from Dr. Sean O’Leary on this morning’s Advisory Committee on Immunization Practices (ACIP) meeting:
Congratulations @AnwaarSaeed3 on your pioneering work! 👏🏽👏🏽👏🏽 I remember how exciting it was to hear you talk about the responses you were seeing on your CAMILLA trial. Can’t wait to 👀 the new data!
🚨 STELLAR-303 makes history! First-ever Ph3 trial to show OS benefit of IO in MSS CRC 🎯 Years of grit & belief led us here 🥹 Endless thanks to Exelixis for the trust & Dr. Hecht for leading this global win with me! 🎉 @UPMCHillmanCC ir.exelixis.com/news-releases/…
📢 Press release drop—interpret with appropriate caution. Exelixis reports that zanzalintinib + atezolizumab improved overall survival vs regorafenib in the Phase 3 STELLAR-303 trial for third-line MSS metastatic colorectal cancer. This isn’t the highest bar—survival in this…
We’ll have short talks, cases and lots of multidisciplinary discussion! Looking forward to it.
🚨 Not to Miss Free CME Event! 🚨 🗓️ July 9 – LIVE from Cleveland Clinic 🎯 PERSONALIZED APPROACH TO NEOADJUVANT THERAPY IN RECTAL CANCER Join @DavidLiskaMD @davidrrosenmd @smitha42 @GIlymphomapath @kgnairmd @CleClinicMD for CME virtual event 🔗 Register bit.ly/LIVECC2025
Lenacapavir, a twice-yearly shot that almost completely prevents HIV, is now approved. It could shut down the HIV pandemic. It needs to roll out in at risk groups. But Trump has gutted HIV prevention at home and abroad. nytimes.com/2025/06/18/hea…
Do the right thing @AnthemBCBS
Hi @AnthemBCBS - I have an ill 45 yo man and we found a needle in a haystack fusion protein to target. Despite an "urgent appeal process" we have not heard back in 3 days on whether we can get this drug in his hands. Pls help us! @fumikochino @marklewismd @DrKelseyKlute
The 17 fired members of ACIP, including me, have written an article in JAMA about our experience and our concerns. jamanetwork.com/journals/jama/…
Tolerance to therapy for patients with early-onset vs average-onset locally advanced rectal ca esmogastro.org/article/S2949-… by @MadisonConces @smitha42 @myESMO Early-onset ➡️ significantly more nausea, fatigue & side effects ➡️Consider enhanced antiemetic prophylaxis
RFK, Jr says “The only vaccine to go through placebo-controlled trials prior to licensure was the COVID vaccine.” This is demonstrably false. Every initial vaccine is evaluated in randomized placebo-controlled trials. When a vaccine is proven safe and effective against placebo it…
RFK Jr is on Fox News going full anti-vax
More than 98% of families in this country choose to vaccinate their young children. But now, vaccine policy is being shaped by the small, extreme minority that doesn’t. This decision doesn’t reflect, protect or support families.
Today's decision is about undermining independent medical expertise and will only further endanger the health of the American public, especially children. bit.ly/43Bwd80