Thomas P Seager, PhD
@seagertp
Health, resilience, & trauma recovery: physiological, psychological, financial & relational. For ice bath info https://www.morozkoforge.com/ice-bath-science
When my PSA test came back 7.0 I thought I was going to die of prostate cancer. Probably, I should've run straight to my urologist so he could remove my prostate, save my life & leave me impotent. No. When faced with a choice between my life & my penis, I chose my penis.

"These parallels suggest sleep pressure and hunger both have mitochondrial origins, and that electrons flow through the respiratory chains of the respective feedback controllers like sand in the hourglass that determines when balance must be restored."
A fascinating paper published in @Nature just two days ago offers a new perspective on sleep drive—through the lens of mitochondria. This paper shows how waking and sleeping oppositely change mitochondrial fusion and fission dynamics; how artificially manipulating fusion and…
When girls were behind in school, society asked, "What's wrong with the system?" and made reforms. Now, as boys have fallen behind, people ask, "What's wrong with boys?" Maybe it’s not them, but us! Education systems must adapt for our boys too, with hands-on learning, more male…
Autism Parenting Secrets #263. Clip#1 Overcome the naysayers.
Super frigid whole-body cryotherapy promotes better sleep quality in both male and female athletes. How?
Cold is great for sleep. "A 3-min single session of whole body cryo in the evening improved the subjective & objective sleep quality in physically active men." tandfonline.com/doi/abs/10.108…
A consistent theme throughout my career has been "I used to think Thomas was really smart, but then he showed me some data I didn't like and now I know for sure he's bad!" Which makes me wonder how the hell I made such a good impression in the 1st place?
When people come out with conclusions like “ackshully men and women are the same” that’s your first clue they’re off the reservation. It should also make you doubt their other work. I have previously thought Thomas was smart and discerning, now I know he’s unyielding to wisdom.
Cold is great for sleep. "A 3-min single session of whole body cryo in the evening improved the subjective & objective sleep quality in physically active men." tandfonline.com/doi/abs/10.108…

Throughout a healthy woman's life, total testosterone levels will exceed estradiol by a factor of 4x or 5x. sciencedirect.com/science/articl…
Testosterone is synthesized from cholesterol in a process that originates inside the mitochondria. Low testosterone in men is a consequence of poor mitochondrial function and it is reversible without exogenous hormones. Did your medical doctor forget to tell you?
"Testosterone is the most abundant biologically active female hormone, essential for physical & mental health in women, and not masculinizing. "Adequate T is essential for physical, mental and emotional health in both sexes." sciencedirect.com/science/articl…
4. Cold exposure Cold showers. Ice baths. Cryo. Brief cold stress boosts luteinizing hormone—your brain’s “make testosterone” signal. Bonus: Activates brown fat, speeds metabolism, and sharpens focus.
Dave is right now catching up to this 27 May announcement from HHS. Good for Dave! Wait until Dave figures out that it doesn't mean what he says it means.
🚨 JUST IN: RFK Jr. has officially REMOVED the COVID shot from the childhood vaccine schedule!
Yes, mitochondrial dysfunction causes sleep apnea. This was demonstrated at least since 2013.
Sleep apnea can be caused by a functional vitamin B2 deficiency... 🧐? "SLC52A3, a riboflavin (vitamin B2) transmembrane transporter that is known to impact Brown-Vialetto-Van Laere and Fazio Londe syndromes. Presentation of these rare disorders can include diaphragmatic and…
Therapies that target mitochondria improve cancer treatment outcomes. "Elevating levels of ketone bodies offers a simple and parsimonious therapeutic strategy for managing most cancers." - @tnseyfried mdpi.com/2218-1989/11/9…
The Breath Hold Index is a reliable measure of CO2 tolerance that indicates resilience -- i.e., readiness to tolerate and recover from stress. In one trial, cold plunge improved it.
TRUTH BOMB: Before glyphosate was patented in 1974, autoimmune and digestive disorders were rare. Today, everybody has “gut issues.” Glyphosate destroys beneficial gut bacteria, disrupts metabolism, and weakens immunity, but people blame gluten intolerance instead of the poison…
How could cold cure cancer? All tumor cells rely on fermentation of either glucose or glutamine to power proliferation. We already know that cold exposure activates brown fat, starves tumors of glucose, inhibits tumor growth, and improves cancer treatment outcomes. How might…
Cancer results from defects in mitochondria, not the DNA in the nucleus. 50 years of NCI research have been looking for cancer cures in the wrong place. @Diary_Of_A_CEO @tnseyfried