Scott Williams

Writing is more than words on a page. It’s how we think, feel, and make sense of the world. As AI takes control of that process more and more, it’s important to remember the power of writing as a deeply human act.

Trying to set standards for MR papers - at least for PLOS Genetics journals.plos.org/plosgenetics/a…

IF ignorance is bliss, why aren't more people happy?

Two questions: What is the right thing to do? and what will doing this cost me? The order in which you ask these questions matters

Finishing grant reviews (Happy 4th). Seems that as an old timer when reviews were narrative they had more substance and were more helpful. Yes harder to write but the process was more transparent compared to often very short bullet points. A precursor to less complex research?

Could there be any better advice if you want to live wholy

Perhaps the biggest impediment to gaining new knowledge is our arrogance about what we think we already know

Figuring ot why data sharing is difficult is difficult itself. Transparency is often a smokescreen? Institutional Characteristics Associated with Accessing and Sharing EHR Data with the National COVID Cohort Collaborative (N3C) medrxiv.org/content/10.110…

Love seeing my former students succeed. Congrats Rafal Sobota A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabol… pubmed.ncbi.nlm.nih.gov/40383794/

Print out a couple of papers. Leave your office/computer and turn off your phone. Then read papers, carefully (including methods). That is how you learn to do science and to write. Do that long enough and then you can read on your computer.

As more data becomes available on more people, why do we limit our conceptualization of complex disease to simple models and testing? For the first time we are able to assess more realistic models, yet often do not do so. Need to get out of 20th century thinking and get real

Were we end up is very often not where we thought we would and that is just fine! Abandoning my long-held career plans was painful—but I love where I landed | Science | AAAS science.org/content/articl…

What does heritability mean as measured multiple ways and what does it mean for our understanding of Alzheimer's? Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review medrxiv.org/content/10.110…

We live in a world of context. Nothing happens in a vacuum and all else is never equal. So why we do we construct models to explain nature ,using models that make assumptions known to be false? And worse, why do we believe them to be true?

Microbiome markers of Alzheimer from Uganda in our recent report Characterization of the gut microbiome in Alzheimer disease and mild cognitive impairment among older adults in Uga… pubmed.ncbi.nlm.nih.gov/40258729/

“Universities need to address legitimate criticisms with humility and openness. But the way to bring about constructive change is not by destroying the nation’s capacity for scientific research, or through the government taking command of a private institution” - Stanford…