Rizwan Romee
@romeerizwan
Cancer immunologist using synthetic biology to target cancer, PI #RomeeLab @DanaFarber @HarvardMed @broadinstitute @parkerici,Views mine
Here we show that the outer membrane of non pathogenic E. coli can be efficiently used to deliver potent biologics including activating cytokines to the TME inducing very strong immune responses. This was approach was safe and more effective than the PD1 blockade or chemotherapy.
Non-pathogenic E. coli displaying decoy-resistant IL18 mutein boosts anti-tumor and CAR NK cell responses - @romeerizwan go.nature.com/4ettzUR
4/ Led by @VincentWenxinXu @graceandscience , with @DrChoueiri @romeerizwan , we report evidence of NK cell dysfunction in advanced RCC @ESMO_Open esmoopen.com/article/S2059-…
Dr. Rizwan Romee (@romeerizwan) from @DanaFarber and @harvardmed is on the @ImmunoPodcast! Tune in to hear him talk about advances and challenges in engineering NK cells for #CancerTherapy. 🎧: bit.ly/43RdLZd
Don't miss this killer episode! Dr. Rizwan Romee (@RomeeRizwan) talks about #NaturalKiller cells and how they can be engineered to target cancers. Check it out: bit.ly/4n7qA96
Excited to share our review on CAR arming of the innate immune cells. Engineering innate immune cells for cancer immunotherapy | Nature Biotechnology nature.com/articles/s4158…
Review @NatureBiotech @romeerizwan et al Engineering innate immune cells for cancer immunotherapy nature.com/articles/s4158…
Excited to attend and speak at this premier meeting by the British Association for Cancer Research (BACR) bacr.org.uk/event/cancer-i…
Super excited to introduce our ImmunoBac system; bacteria based microbots as a novel immunotherapy platform @sitcancer The Spring Scientific, Cellular Therapy for Solid Tumors today. Funded by @parkerici and #MIT_Harvard Bridge grnt @DanaFarber

Happy International Women’s day to the wonderful women @DanaFarber_GU at @DanaFarber !
At the @DanaFarber_GU we enjoy very much collaborating closely with @romeerizwan lab on all sort of Natural Killer Cells projects ! @DanaFarber @DanaFarberNews @harvardmed and we share our passion for ⚽️! #beatFabrice
Two amigos on a mission to conquer kidney cancer!! @DrChoueiri @DanaFarber @DanaFarber_GU @Romee_Lab #NK #immunotherapy #KidneyCancer
Two amigos on a mission to conquer kidney cancer!! @DrChoueiri @DanaFarber @DanaFarber_GU @Romee_Lab #NK #immunotherapy #KidneyCancer

The latest collaboration led by the @kaelin_lab and #WuLab with @BraunMDPhD, #SteveCarr, #DerinKeskin @VanAllenLab @DanaFarber_GU @harvardmed @MIT @df_hcc in @CellCellPress: HIF-2, ERV, T cells, HLA, renal cell carcinoma, et al…. sciencedirect.com/science/articl…
Thrilled to share our paper, "First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer". A big thank you to Roman Shapiro, Rizwan Romee @romeerizwan, Glen Hanna @HeadNeckMD and all co-authors.
Excited to share our paper, where we combined N-803 with ipililumab (to target Tregs) with allogeneic memory-like NK cells in advanced head and neck cancer. #NK cells #immunotherapy @Romee_Lab @HeadNeckMD @DanaFarberNews
First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer @romeerizwan @Roma_Shap @MichalSheffer @HeadNeckMD jhoonline.biomedcentral.com/articles/10.11…
Amazing work!! Congratulations team
@BraunMDPhD, @DrChoueiri, and team tested a neoantigen-targeting personalized cancer vaccine (PCV) in patients with stage III/IV renal cell carcinoma (RCC). This Phase I trial highlights the promise of PCVs as effective adjuvant therapy in RCC. 🩺 🔗 go.nature.com/3Q9aMUd
4. Serial CD45-PET imaging provides reliable insights into changes in the inflammatory profile of specific tissues, accurately reflecting disease severity. We have also developed a human CD45-PET for clinical translation.
One of the first clinical trials in the US to test ‘memory-like’ NK cells in ovarian cancer - @DanaFarber @romeerizwan oncodaily.com/blog/224193 #Health #Medicine #Cancer #OncoDaily #Oncology #OvarianCancer #ClinicalTrials #MedX
Our translational paper about Natural Killer Cells function (or dysfunction) in RCC in @ESMO_Open ! Take a look @VincentWenxinXu thread! Collaboration with @romeerizwan @DanaFarberNews + @BraunMDPhD @YaleCancer cc: @DanaFarber @DanaFarber_GU @OncoAlert @MarcMachaalani…
1/8 Our study on natural killer (NK) cell dysfunction in kidney cancer is now out @ESMO_open! Led by co-first authors @graceandscience and @aliameliki, and mentored by @romeerizwan, @drchoueiri, @BraunMDPhD. Link here 👇 sciencedirect.com/science/articl…
Super excited to publish this wonderful collab with @DrChoueiri @VincentWenxinXu and @BraunMDPhD #NK #kidneycancer #Immunotherapy
1/8 Our study on natural killer (NK) cell dysfunction in kidney cancer is now out @ESMO_open! Led by co-first authors @graceandscience and @aliameliki, and mentored by @romeerizwan, @drchoueiri, @BraunMDPhD. Link here 👇 sciencedirect.com/science/articl…
iPSC-derived CD19 CAR NK cells for relapsed or refractory lymphoma @TheLancet Comment @romeerizwan doi.org/10.1016/S0140-… doi.org/10.1016/S0140-…