Rishab Ramapriyan, MD

🚨1/8 Excited to share the final version of our #meningioma #mesothelin #CART-cell paper, now published @NeuroOnc with corrected proofs! This preclinical work lays the foundation for applying CAR T-cell therapy to aggressive and treatment-refractory meningiomas. Highlights ⬇️

Paving the way for trials of mesothelin CAR T-cell therapy in patients with refractory meningiomas The one and only @rishabrama & co @MGBneurosurgery -- eager to see how you push neuro CAR T-cells forward @PennNSG !

Congrats to the 2025 NREF Medical Student Summer Research Fellows! These rising stars are shaping neurosurgery’s future. 2026 applications open Sept. 1. #medicalstudent #MedEd #MedTwitter ow.ly/KeC450WjS78 @MegBhimreddy @allieheinemann @minjicindykoh @SaketMyneni

Congrats @rishabrama and collaborators @MGBneurosurgery on our work developing Meso-CAR T cells for refractory meningiomas, published this week @NeuroOnc! doi.org/10.1093/neuonc…

In a Science study last year in mice, researchers introduced CHARM, a compact and versatile epigenetic editor that can be used to silence prion protein throughout the brain. Learn more in this #SciencePerspective: scim.ag/3IBm0jz

A Technical Assessment of a Commercial GFAP Lateral Flow Assay to Establish Proof-of-Concept for Use in Traumatic Brain Injury | Cellular and Molecular Neurobiology ⁦@UpfrontDx⁩ link.springer.com/article/10.100…

New review in @trendscancer: #NAD⁺ decline with age impairs #CAR_T cells—restoring it may boost #CAR_T response in older patients. Featuring #PIIO's @ruoning_wang 🔋🧬 📖 pubmed.ncbi.nlm.nih.gov/40571557/ #CAR_T #NADplus #CancerResearch #Aging

A very cool "pre-clinical-trial-on-chip" tool for CAR T cell development by Chao Ma and Weiqiang Chen (@nyutandon)...with a small help from Matt Witkowski and our lab! nature.com/articles/s4155…

The report opens up a new avenue of therapy for refractory #meningiomas using #Car T cell therapy, using a surface antigen found in all meningiomas, #mesothelin, with intracerebral intraventricular (ICV) delivery of #CAR T cells, in a novel mouse model, with exceptional survival…

Kudos to Rishab Ramapriyan, MD, @rishabrama, Penn Neurosurgery resident, @PennNSG, as first author of a current, impactful, innovative study @NeuroOnc with Marcela Maus, MD, PhD, and Bryan D. Choi, MD, PhD and colleagues @MGBneurosurgery on a novel approach using #CAR T cell…

Exciting new paper from @rishabrama @BryanDChoi et al. showing that mesothelin-specific CAR T-cells are effective in meningioma orthotopic xenografts. @NeuroOnc academic.oup.com/neuro-oncology…

Proud to have been part of this study led by @kevin_sek, @paulbeavis4 & Phil Darcy in @NatureComms now! We showed that tumour-specific expression of A1R in CAR T cells protects against adenosine-mediated exhaustion, and enhances anti-tumour efficacy. 1/5 nature.com/articles/s4146…

Excited to share that my PhD work is out in @Nature today! We engineered armoured CAR T cells to express therapeutic payloads only at the tumour site, to improve their safety and efficacy for the treatment of solid cancers. 1/14 nature.com/articles/s4158…