Puglisi Labs

The application portal is now open for our incredible 2025 Erice Meeting “Frontiers in Biophysics” It is a broad meeting covering many aspects of modern biophysics—from structure to computation to imaging to genomics and beyond. #ilovescience #biophysics

Barney Graham @BarneyGrahamMD demonstrates how HIV research and pandemic preparedness efforts paved the way to developing SARS-CoV-2 vaccines. Now, we need to invest in #HIVresearch to understand HIV, and to provide research tools of other viruses. #HIV #SARSCoV2 #RSV #CROI2024

Fantastic talk by Gabriel Ozorowski @GabeOzorowski about how Cryoelectron Microscopy-Based Polyclonal Epitope Mapping (#cryoEMPEM) can be applied to HIV vaccine research. #HIV #CryoEM #CROI2024 Read more at these papers here: shorturl.at/oyT35 shorturl.at/gmwY6

eIF1 and eIF5 dynamically control translation start site fidelity biorxiv.org/cgi/content/sh… #biorxiv_biophys

An important work led by @C_P_Lapointe @puglisilab & Dever lab showing how eIFs1/5 regulate start codon selection via their dynamic interactions with the initiating ribosomal complexes, textbook knowledge here👏👇

Joined the conference/summer school“Frontiers in Biophysics” July 19-24, 2024 in Erice, Sicily. Beautiful city, friendships and sciences. Highly recommended! (This is annually organized by @puglisilab )

New synthetic biology / molecular recording lab opening in the New York city, and we are hiring at all levels (research tech / grad student / postdoc), so please reach out to me via choij10 _at_ mskcc.org!

New paper! We provide a scRNA-seq pipeline for simultaneous gene expression and 3′UTR length analysis. We quantified 3′UTRs in 474 cell types and found that 3′UTR length provides information that is independent of gene expression. nature.com/articles/s4146…

Why can RNA only be linear or circular? It can be branched! We made multi-tailed mRNA, and we had fun! Here is our story led by brilliant graduate student @HongyuChenChem: rdcu.be/dB7ck and his cartoon illustration👇@ChemistryMIT @broadinstitute

Our annual #SummerSchool “Frontiers in Biophysics” will be held July 19-24, 2024 in Erice, Sicily.🌞 It is a wonderful venue for #science, #discussions and the latest advances in a broad range of #biophysics. There is limited space, please apply soon here: puglisi.stanford.edu/erice2024/

Exciting summer school in Italy on Frontiers in Biophysics and Structural Biology with super speakers (@MoAlQuraishi and many more) and organized by @puglisilab! puglisi.stanford.edu/erice2024/

Today's inaugural STEMfest welcomed thousands of people to @Stanford campus, and we had an amazing time sharing our science with over 200 visitors! We led 8 lab tours (with demos!) and hands-on activities with heat-responsive polymers (shrinky-dinks).@StanfordEng @StanfordPolymer

Interested in the link between alterations in tRNA modification pattern, gene expression programs and pathogenicity of Pseudomonas aeruginosa - read our new story @PNASNews - a wonderful collaboration with the team of Susanne Häussler | pnas.org/doi/10.1073/pn…

Frank Mugisha @frankmugisha implores: Scientists, we need your voice. Scientists, we need your solidarity. Scientists, speak up. #HIV #CROI2024 #endhomophobia

Dorothy Mbori-Ngacha @DeeMboriNgacha implores us to end HIV in children by remembering: Our why. To be patient. We need all our tools, the science, the implementation, the community. That the journey is as important as the destination. #HIV #HIVpediatric #HIVinkids #CROI2024

Great talk by Iain Clark @icclarker, highlights the single-cell multi-omics capabilities applicable to HIV research and develops new cell sorting seq methods. #HIV #sequencing #HIVcellsorting #FINDseq #PIPseq #CROI2024. Read more: nature.com/articles/s4158… nature.com/articles/s4158…

A great talk by Kevin Welsher @WelsherLab about the capabilities to image HIV using fluorescence microscopy. #HIV #microscopy #HIVentry #CROI2024 Read more here: nature.com/articles/s4159…

Fantastic talk by Barbara Müller about visualizing HIV viral post-entry events by Correlative Light and Electron Microscopy #CryoEM #CLEM #HIV #CROI2024. Read more in these papers: shorturl.at/lqrMT elifesciences.org/articles/64776

Fantastic talk about how to do the research you are passionate about by Jeanne Marrazzo @DrJeanneM at #CROI2024. Seek good mentors! Pursue the science questions that are interesting to you! Take care of yourself ❤️! #HIV #HIVresearch #HIVhistory #ActUp